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TISSUE TRANSGLUTAMINASE ANTIBODY IGA Test results

Luashlee
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Luashlee Newbie
Luashlee
Posted

I have type 1 diabetes so I receive a Celic test every 4 years. 
 

my TISSUE TRANSGLUTAMINASE ANTIBODY IGA seem to have gone up since 4 years ago. 
 

2019: .4 

2024: .6 

I am wondering if this number is increasing does that mean I am developing celiac/my body is fighting gluten? 
 

I’ve always known have a wheat intolerance per a food allergy test but it’s common for type 1 diabetics to develop celiac so I am just looking for some insight! Thanks!

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trents Grand Master
trents
Posted

Welcome to the forum, @Luashlee!

You do understand that celiac disease is not an allergy but an autoimmune disorder, right? Just checking because you mention having a wheat allergy.

Do you know if the blood samples are being tested by the same lab every time? Different labs concoct these tests differently and used different scales. There is not an industry standard. So, can you include the scale they used for negative vs. positive for the test from 4 years ago and for the most recent one in your next post? The edit window for making changes to a post has a very short timer so you likely cannot go back and add the info to your original post.

Luashlee Newbie
Luashlee
Posted
  • Author

@trents I do yes, I was just mentioning the allergy.

they have been done by the same lab each time. 
 

they say: 

less than .7 = negative

but my question is since it was .4 last time and .6 now is that usually an indication of developing celiac even though it’s negative considering the lab value 

trents Grand Master
trents
Posted

First, realize that you only have two data points to go from so I would not consider that enough to constitute a trend. What you are looking for is a trend and two data points is not enough to establish a trend. Second, all lab values fluctuate somewhat from time to time. That is normal. The next time you get it assessed it might be lower than either of the first two scores. Third, it's still a negative value.

My concern is that you are only being tested every four years. A lot can happen in that amount of time. I would advocate to have that stepped up to annually. It is also true that having diabetes can artificially suppress the TTG-IGA score.

Scott Adams Grand Master
Scott Adams
Posted

How much gluten were you eating daily before the tests were taken? It should have been at least two slices of wheat bread worth of gluten for 6-8 weeks beforehand.

If you were eating less, then the results might be lower than they otherwise would have been, had you been doing a proper gluten challenge.

 

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