Don’t understand lab results..Help please

[RondaM]

Recent Labcorp lab results show these results.

Endomysial Antibody IgA:  Negative

t-Transglutaminase (tTG):  <2 

Range for tTG lab is :  negative= 0-3, weak positive =4-10 ,  Positive >10

Immunoglobulin A, Qn  Serum :  417.  H
lab range 87-352 mg/dl

What is this telling me? Any recommendations?
 

 

 

[trents]

Welcome to the forum, @RondaM!

These two tests are celiac antibody tests and they both look to be negative:

Endomysial Antibody IgA:  Negative

t-Transglutaminase (tTG):  <2

We commonly refer to the t-Transglutaminase (tTG) as tTG-IGA.

 

This one is what we commonly call "total IGA" and is on the high side: 

Immunoglobulin A, Qn  Serum :  417.  H

Total IGA is not an antibody test for celiac disease per se but the reason it is run is that if it is on the low side (i.e., you are "IGA deficient") it can cause the individual IGA tests that are designed to check for celiac disease per se to be falsely negative. This is not a problem in your case. I do not know that there are any particular health concerns connected to having a higher than normal total IGA.

Based only on these IGA tests it does not appear that you have celiac disease but it is unfortunate that only IGA tests were ordered. I would have been helpful to also include the DGP-IGG test. Some people who truly do have celiac disease just have immune systems that don't throw positives for IGA celiac antibody tests.

But here is an important question. Had you already begun limiting gluten in your diet before the blood draw for the testing was done? If so, it rendered the testing invalid.

 

[Scott Adams]

Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.

[RondaM]

Thank you for your feedback.  I was not eating gluten free at time the lab was taken.  Have been gluten free now for a week. How long might it take for symptoms to go away. Only issue I have is loose stool.

thanks again,,
 

[trents]

If gluten is the problem or the only problem I should say, your stools should have normalized by now. But many in the gluten intolerant/gluten sensitive population are also dairy intolerant. Try eliminating dairy from your diet and see if the issues improve.