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Best Lab To Get Full Panel Bloodwork For Accurate Celiac Results


cillivilli
Go to solution Solved by trents,

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cillivilli Newbie

I read that different labs use different testing techniques which can effect TTg-Iga results. Which Lab should I have my TTg-Iga blood test and which one does a full panel test?


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  • Solution
trents Grand Master

The antibody blood tests used to diagnose celiac disease are standardized in the sense of what is being measured. How the tests are conducted and the scales used (as well as the units used) to express the results can vary from lab to lab. This does not affect the accuracy of the testing. So, there shouldn't be an issue with choosing one lab over another to ensure testing accuracy. What you don't want to do is to compare test results from two different time periods done by two different labs. If you are wanting to compare blood antibody test results over time, then the tests would need to have been done by the same lab in order for the comparison to be meaningful. And by the way, the TTG-IGA is not the only celiac antibody test that can be run nor is the only one that should be run. At least a "total IGA" test should be ordered whenever the tTG-IGA is ordered to make sure the tTG-IGA result is not invalidated by IGA deficiency. Here is an article outlining the various tests that can be ordered to diagnose celiac disease: 

 

 

 

Scott Adams Grand Master

I agree with @trents, but for genetic tests it does seem like there are some variations between different labs and the celiac gene markers that are included, but for your celiac disease blood test just make sure that a full celiac disease panel is done that includes total IgA.

cillivilli Newbie

Thank you @trents and @Scott Adams your input was very helpful! 

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      Cristiana, that sounds like a great approach and I will be looking forward to the results. I am in the same boat as you. I don't experience overt symptoms with minor, cross contamination level exposures so I sometimes will indulge in those "processed on equipment that also processes wheat . . ." or items that don't specifically claim to be gluten free but do not list gluten containing grains in their ingredient list. But I always wonder if I am still experiencing sub acute inflammatory reactions. I haven't had any celiac antibody blood work done since my diagnosis almost 25 years ago so I don't really have any data to go by.   
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