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Best Lab To Get Full Panel Bloodwork For Accurate Celiac Results


cillivilli
Go to solution Solved by trents,

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cillivilli Newbie

I read that different labs use different testing techniques which can effect TTg-Iga results. Which Lab should I have my TTg-Iga blood test and which one does a full panel test?


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  • Solution
trents Grand Master

The antibody blood tests used to diagnose celiac disease are standardized in the sense of what is being measured. How the tests are conducted and the scales used (as well as the units used) to express the results can vary from lab to lab. This does not affect the accuracy of the testing. So, there shouldn't be an issue with choosing one lab over another to ensure testing accuracy. What you don't want to do is to compare test results from two different time periods done by two different labs. If you are wanting to compare blood antibody test results over time, then the tests would need to have been done by the same lab in order for the comparison to be meaningful. And by the way, the TTG-IGA is not the only celiac antibody test that can be run nor is the only one that should be run. At least a "total IGA" test should be ordered whenever the tTG-IGA is ordered to make sure the tTG-IGA result is not invalidated by IGA deficiency. Here is an article outlining the various tests that can be ordered to diagnose celiac disease: 

 

 

 

Scott Adams Grand Master

I agree with @trents, but for genetic tests it does seem like there are some variations between different labs and the celiac gene markers that are included, but for your celiac disease blood test just make sure that a full celiac disease panel is done that includes total IgA.

cillivilli Newbie

Thank you @trents and @Scott Adams your input was very helpful! 

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      Welcome to the the celiac.com community @colinukcoeliac! I am in the USA but I don't think it is any different here in my experience. In some large cities there are dedicated gluten free restaurants where only gluten free ingredients are found. However, there are a growing number of mainstream eatery chains that advertise gluten free menu items but they are likely cooked and prepared along with gluten containing foods. They are just not set up to offer a dedicated gluten free cooking, preparation and handling environment. There simply isn't space for it and it would not be cost effective. And I think you probably realize that restaurants operate on a thin margin of profit. As the food industry has become more aware of celiac disease and the issue of cross contamination I have noticed that some eateries that used to offer "gluten free" menu items not have changed their terminology to "low gluten" to reflect the possibility of cross contamination.  I would have to say that I appreciate the openness and honesty of the response you got from your email inquiry. It also needs to be said that the degree of cross contamination happening in that eatery may still allow the food they advertise as gluten free to meet the regulatory standards of gluten free advertising which, in the USA is not more than 20ppm of gluten. And that is acceptable for most celiacs and those who are gluten sensitive. Perhaps you might suggest to the eatery that they add a disclaimer about cross contamination to the menu itself.
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      Welcome to the forum @colinukcoeliac. Letting them know that they lost a customer because they could not satisfy cross contamination needs may incline them to fix that problem.  It was good of tnem to alert you.  The more they know...
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