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Omeprazole 20mg capsules prescription


Jherm21

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Jherm21 Community Regular

Hello, 

I have had celiac for about 7 years and I'm confused about a medication. And asking my doctors or pharmacy about ingredients etc they just seem to think everything is gluten free. So I decided to come here and see if any fellow celiac knows how to move forward with taking this specific manufactured prescription or suggestions on what to do with the information the manufacturer gave me. I was recently diagnosed with GERD (through endoscopy) and my doctor prescribed omeprazole 20 mg capsules. She told me the prescription is different than otc because it can be safer to take for a longer period of time. Which time is what I need to heal the esophagus. But the manufacture through xiromed stated "the medication is formulated without intended gluten ingredients, but states one of the inactive ingredients polysorbate 80 may be derived from "wheat, corn or olives" which she could not tell me if it was made from wheat or not. I'm so confused and don't know what to do with that information. Help!!!! 


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RMJ Mentor

To manufacture polysorbate 80 requires multiple chemical reaction steps.  Even if one of the chemicals used to make it was derived from wheat, it would be highly unlikely that any gluten would still be there at the end.  Plus it is a partway down on the list of inactive ingredients in omeprazole, so there won’t be a huge amount of polysorbate 80 in each pill.

Jherm21 Community Regular

Ok thanks for the response. Assuming, this would be safe then? 

RMJ Mentor
4 hours ago, Jherm21 said:

Ok thanks for the response. Assuming, this would be safe then? 

I am a sensitive celiac and would not hesitate to take it.

  • 2 weeks later...
Holli Madsen Newbie
On 10/22/2024 at 1:30 PM, Jherm21 said:

Hello, 

I have had celiac for about 7 years and I'm confused about a medication. And asking my doctors or pharmacy about ingredients etc they just seem to think everything is gluten free. So I decided to come here and see if any fellow celiac knows how to move forward with taking this specific manufactured prescription or suggestions on what to do with the information the manufacturer gave me. I was recently diagnosed with GERD (through endoscopy) and my doctor prescribed omeprazole 20 mg capsules. She told me the prescription is different than otc because it can be safer to take for a longer period of time. Which time is what I need to heal the esophagus. But the manufacture through xiromed stated "the medication is formulated without intended gluten ingredients, but states one of the inactive ingredients polysorbate 80 may be derived from "wheat, corn or olives" which she could not tell me if it was made from wheat or not. I'm so confused and don't know what to do with that information. Help!!!! 

I am sensitive celiac and I take omeprazole no problem.

trents Grand Master

Holli Madsen, be aware that it can be difficult to wean off of PPIs once you have been on them for an extended period of time. There is typically a rebound of GERD when going off after being on them for long periods of time. They are designed to be a short term remedy to be taken for weeks but many physicians put their patients on PPIs and leave them on for life with no monitoring. They generally work well for the intended purpose but because of how they work they can and will cause other problems when used long term. They increase gut PH (i.e., they lower acidity) which can help ulcers and irritated/inflamed areas to heal but this also interferes with nutrient absorption, something celiacs already struggle with. This can lead to osteoporosis/osteopenia and other nutrient malabsorption-related medical problems. Lowering gut acidity can also make you more prone to gut infections. Don't stay on the PPI any longer than necessary.

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