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Progesterone pills - are they gluten free??

Mettedkny
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Mettedkny Newbie
Mettedkny
Posted

Not sure where to start - been diagnosed for 17 years, and for 16 years my bloodwork has been perfect. Last May I started on HRT (estrogen patch & progesterone pill) for post menopausal symptoms, and to help with mild osteoporosis.
In June my Gliadin IgG numbers suddenly went up to 59 (from previously being below 5 for 16 years). Did a deep dive on the progesterone pill manufacturer (Aurobindo) to ensure that the medication IS gluten free - and was told multiple times that there is no gluten in the pills.
The pill is the ONLY thing that has changed, and my son, who is also celiac has perfect numbers. 
Scoured my life to try and find out where the gluten could be coming from and the only thing I found was a tea I drank that had "possible wheat straw" (had been drinking this tea for about 5 years with no issues - and was confirmed by the manufacturer that their tea is certified gluten-free despite the "straw") - cut the tea out thinking that it MUST be the tea. Repeated the blood test 3 months later and it dropped to 55 - not indicative that the gluten has been found and removed from my diet.
Had bloodwork done again yesterday and it is now 95 😳
I am completely floored. WHERE is it coming from??? I am SO careful. Would NEVER cheat, don't eat out and like I said, my son has NO issues and his number is 3 (as of yesterday).
Has anyone had a problem with progesterone pills? It is the only variable that I can think of, but how do I prove that it is the problem without discontinuing to take the HRT (which I really need for post menopausal symptoms, sleep, anxiety, brain fog and hot flashes).

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trents Grand Master
trents
Posted

Welcome to the forum, @Mettedkny!

Your ttg-igg numbers are elevated but what about your ttg-iga numbers? Were your ttg-iga numbers elevated at your original diagnosis? The reason I ask is because elevated igg antibody test scores are more likely to be caused by something else besides a celiac reaction to gluten. The ttg-iga test is considered to be the centerpiece of celiac disease blood antibody testing. But some people are seronegative for the iga celiac tests, particularly if they are iga deficient. If they are iga deficient, the igg tests can be helpful. Have you ever had a "total iga" test run to check for iga deficiency?

Scott Adams Grand Master
Scott Adams
Posted

You can search this site for prescriptions medications, but will need to know the manufacturer/maker if there is more than one, especially if you use a generic version of the medication:

To see the ingredients you will need to click on the correct version of the medication and maker in the results, then scroll down to "Ingredients and Appearance" and click it, and then look at "Inactive Ingredients," as any gluten ingredients would likely appear there, rather than in the Active Ingredients area.

 

Mettedkny Newbie
Mettedkny
Posted
  • Author
12 minutes ago, Scott Adams said:

You can search this site for prescriptions medications, but will need to know the manufacturer/maker if there is more than one, especially if you use a generic version of the medication:

To see the ingredients you will need to click on the correct version of the medication and maker in the results, then scroll down to "Ingredients and Appearance" and click it, and then look at "Inactive Ingredients," as any gluten ingredients would likely appear there, rather than in the Active Ingredients area.

 

Thank you Scott, I have looked at the ingredients (and also spoke to Aurobindo, the manufacturer) and all looks like it should be (and I'm being told is) manufactured without gluten - BUT - wondering if it could be cross contaminated.

Scott Adams Grand Master
Scott Adams
Posted

It is very doubtful that prescriptions medications would be cross-contaminated. It's not impossible, but most companies make many different medications and have very strict protocols for their manufacture.

Mettedkny Newbie
Mettedkny
Posted
  • Author
13 hours ago, trents said:

Welcome to the forum, @Mettedkny!

Your ttg-igg numbers are elevated but what about your ttg-iga numbers? Were your ttg-iga numbers elevated at your original diagnosis? The reason I ask is because elevated igg antibody test scores are more likely to be caused by something else besides a celiac reaction to gluten. The ttg-iga test is considered to be the centerpiece of celiac disease blood antibody testing. But some people are seronegative for the iga celiac tests, particularly if they are iga deficient. If they are iga deficient, the igg tests can be helpful. Have you ever had a "total iga" test run to check for iga deficiency?

Thank you for your message. Still waiting for the ttg numbers to come back. So far I know that it were my Gliadin IgG number and the IgA number that was elevated, and the IgG number by a LOT.
My numbers have been consistently "perfect" for 16 year, and just recently (in the past 9 months) have become wonky...

50 minutes ago, Scott Adams said:

It is very doubtful that prescriptions medications would be cross-contaminated. It's not impossible, but most companies make many different medications and have very strict protocols for their manufacture.

I def agree Scott - just grasping for straws (and not the wheat ones lol). Trying to look for ANY variable that might be the reason for my wonky numbers.

trents Grand Master
trents
Posted
(edited)

I agree with Scott. This same question has been asked many times on the forum and for the reasons Scott stated the consensus is that there it is very unlikely that cross contamination is occurring in these scenarios.

Hey, looking forward to hearing back about your igg and iga numbers. We would need the reference ranges as well as different labs used different reference ranges for negative vs. or normal vs. high.

Edited by trents
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Mettedkny Newbie
Mettedkny
Posted
  • Author
1 minute ago, trents said:

I agree with Scott. This same question has been asked many times on the forum and for the reasons Scott stated the consensus is that there it is very unlikely that cross contamination is occurring in these scenarios.

Hey, I didn't hear back from about your antibody test numbers.

So sorry - just replied a minute ago. Not sure if I ever had a total IgA test done for deficiency, but since I have had perfect numbers in the past, wouldn't it be redundant?

trents Grand Master
trents
Posted

No, if you are IGA deficient, your IGA celiac antibody test numbers will be lower than they ought to be so they should not be relied upon if they are in the normal range.

Mettedkny Newbie
Mettedkny
Posted
  • Author
1 minute ago, trents said:

No, if you are IGA deficient, your IGA celiac antibody test numbers will be lower than they ought to be so they should not be relied upon if they are in the normal range.

So far the numbers, and references that I have are:
Gliadin (Deamidated)Ab (IgA) <15.0 Antibody not detected > or = 15.0 Antibody detected
Gliadin (Deamidated)Ab (IgG) <15.0 Antibody not detected > or = 15.0 Antibody detected

now waiting on the Tissue Transglutaminaseab, IgA

Just now, Mettedkny said:

So far the numbers, and references that I have are:
Gliadin (Deamidated)Ab (IgA) 3.3  (<15.0 Antibody not detected > or = 15.0 Antibody detected)
Gliadin (Deamidated)Ab (IgG) 95.1 (<15.0 Antibody not detected > or = 15.0 Antibody detected)

now waiting on the Tissue Transglutaminaseab, IgA

 

trents Grand Master
trents
Posted

Gliadin (Deamidated)Ab (IgA) is DGP-IGA. You really need to have a total IGA done.

This might be helpful. As you can see, terminology varies from place to place but this article pretty much lays out all the options in that regard.

 

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