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- trents replied to TerryinCO's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms6New Guy Here...
There are other possible causes or damaged small bowel villi besides celiac disease. Google this: Not All That Flattens Villi Is Celiac Disease: A Review of Enteropathies There is also something known as seronegative celiac disease: https://pmc.ncbi.nlm.nih.gov/articles/PMC4586545/ -
- ShariW posted a topic in Coping with Celiac Disease0Not All Corn Grits are Safe
Quaker corn grits are not certified gluten-free! These may, in fact, be contaminated by cross-contact in the manufacturing process. I have been following a strict gluten-free diet for about 3 years, with varying results depending on cross-contact issues. My celiac testing was inconclusive - and I wasn't willing to go back on gluten long enough for a full... -
- Whyz posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms0Test
Had my endoscopy yesterday I was told it would be about 6 weeks for the results.. Also found a small H Hernia only small they won’t be doing anything about that about that. -
- TerryinCO replied to TerryinCO's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms6New Guy Here...
This is going to be a long post... Thank you for your time/expertise reviewing this. TTG (Anti-Tissue Transglutaminase) IgA Quantitative Normal range: below <4.0 U/mL Value <4.0 A negative result indicates that celiac disease is unlikely. If suspicion for celiac disease is strong then supplemental testing may be warranted. Concentration... -
- trents replied to TerryinCO's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms6
New Guy Here...
Thanks for the additional info, @TerryinCO. Can you give the reference ranges for the celiac antibody tests. The scores you posted are not of much value without reference range numbers since there are not industry standards for these tests as far as the the scales they use. What they are testing for is the same but how they concoct the tests is a little different...
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There are other possible causes or damaged small bowel villi besides celiac disease. Google this: Not All That Flattens Villi Is Celiac Disease: A Review of Enteropathies There is also something known as seronegative celiac disease: https://pmc.ncbi.nlm.nih.gov/articles/PMC4586545/ -
Quaker corn grits are not certified gluten-free! These may, in fact, be contaminated by cross-contact in the manufacturing process. I have been following a strict gluten-free diet for about 3 years, with varying results depending on cross-contact issues. My celiac testing was inconclusive - and I wasn't willing to go back on gluten long enough for a full celiac diagnosis. I get pretty severe symptoms just a few hours after ANY gluten ingestion, no matter how small, so gastrointestinal doc recommends continuing to follow a gluten-free diet. So whether I have celiac disease (I do have one celiac gene) or non-celiac gluten sensitivity, treatment is the same. I have enjoyed corn grits on occasion, but started seeing a pattern of gluten intake symptoms after large family breakfasts. This last time, I researched everything I might have ingested. My family is pretty good about cross-contact, too. When I got to the Quaker corn grits, I found they are not certified gluten-free, and the labeling does not say gluten free anywhere - although the only ingredients are corn grits, salt and some vitamins and minerals. The research I did confirms that while Quaker grits do not "contain" gluten ingredients, they may indeed be contaminated by cross-contact with glutens. I threw out all the grits (and corn meal) I had in the pantry, and bought some certified as gluten-free. Hopefully, next family breakfast will be better! 😋
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This is going to be a long post... Thank you for your time/expertise reviewing this. TTG (Anti-Tissue Transglutaminase) IgA Quantitative Normal range: below <4.0 U/mL Value <4.0 A negative result indicates that celiac disease is unlikely. If suspicion for celiac disease is strong then supplemental testing may be warranted. Concentration Interpretation: <4.0 U/mL: Negative 4.0-10.0 U/mL: Weak Positive >10.0 U/mL: Positive Endomysial IgA Titer Normal value: <1:10 Value <1:10 INTERPRETIVE INFORMATION: Endomysial Antibody, IgA Titer The endomysial antigen has been identified as the protein cross-linking enzyme known as tissue transglutaminase. Performed By: ARUP Laboratories 500 Chipeta Way Salt Lake City, UT 84108 Laboratory Director: Jonathan R. Genzen, MD, PhD CLIA Number: 46D0523979 Tissue Transglutaminase IgG Antibody Normal range: 0.00 - 4.99 FLU Value <0.82 INTERPRETIVE INFORMATION: Tissue Transglutaminase Ab, IgG In individuals with low or deficient IgA, testing for tissue transglutaminase (tTG) and deamidated Gliadin (DGP) antibodies of the IgG isotype is performed. Positive tTG and/or DGP IgG antibody results indicate celiac disease; however, small intestinal biopsy is required to establish a diagnosis due to the lower accuracy of these markers, especially in patients without IgA deficiency. Performed By: ARUP Laboratories 500 Chipeta Way Salt Lake City, UT 84108 Laboratory Director: Jonathan R. Genzen, MD, PhD CLIA Number: 46D0523979
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Thanks for the additional info, @TerryinCO. Can you give the reference ranges for the celiac antibody tests. The scores you posted are not of much value without reference range numbers since there are not industry standards for these tests as far as the the scales they use. What they are testing for is the same but how they concoct the tests is a little different from lab to lab. You will need to repost the original numbers as well as the reference ranges in a new post as you will not be able to edit the original post. Also, unfortunately, it doesn't seem your doctor ordered a "total IGA" test to determine of you are IGA deficient. If there is IGA deficiency, test scores for individual IGA celiac antibody tests will be artificially low. You mention that there are genetic tendencies on your mother's side for thyroid problems. Perhaps there is also an inherited tendency for celiac disease on that side as well. It's only in the last couple of decades has the medical community begun to understand that celiac disease has long fingers that extend far beyond gut symptoms.
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