Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Health Quality Of Life

DrMom

By DrMom
in Related Issues & Disorders

Recommended Posts

DrMom Apprentice
DrMom
Posted

HRQoL impaired in celiac patients despite GFD adherence

07 July 2006

Eur J Gastroenterol Hepatol 2006; 18: 747-754

Despite adherence to a gluten-free diet (GFD), the majority of German celiac disease patients still experience a significant number of general and extra-intestinal symptoms, and a reduced health-related quality of life (HRQoL), researchers say.

Although there is a high prevalence of celiac disease in Europe, only a small number of studies on HRQoL have been conducted using validated instruments with clinical samples, the scientists state.

To address this imbalance, the team questioned 446 patients with biopsy-proven celiac disease. The participants were aged an average of 46 years and 78% were female.

Questionnaire data indicated that 67% of individuals adhered to a GFD all the time and 26% adhered most of the time.

Furthermore, results demonstrated that after adherence to a GFD for a median period of 6 years, 98% of patients reported a reduction of initial symptoms, and 85% declared that they had experienced an increase in HRQoL. A median weight gain of 8 kg as a consequence of a GFD was recorded.

The most prevalent diseases suffered by the patients were osteoporosis (15%), oral aphtae (12%), and dermatitis herpetiformis (9%).

Interestingly, compared to a control sample of individuals from the German population, celiac patients showed significantly higher scores for anxiety, fatigue, dyspeptic and musculoskeletal pain on the Hospital Anxiety and Depression Scale.

Celiac disease sufferers also showed a reduced HRQoL in nine out of 10 scales of the Medical Outcomes Study Short-Form 36.

Winifred Häuser, from the Klinikum Saarbrücken in Germany, and colleagues conclude that "HRQoL, although improved after starting a GFD, is still reduced compared to that of the general population."

"Further research is necessary to identify risk factors of a reduced HRQoL in celiac patients in order to develop tailored therapeutic interventions."

The research was published in the European Journal of Gastroenterology & Hepatology.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      127,664
    • Most Online (within 30 mins)
      7,748
    Bevmay
    Newest Member
    Bevmay
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      70.3k
  • Celiac.com Sponsor (A22):



  • Who's Online (See full list)

  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Rebeccaj
      glutened?

      By Rebeccaj · Posted

      glutened peoples experience ?via flour airbourne.
    • eKatherine
      Did I outgrow celiac

      By eKatherine · Posted

      Keep in mind that you might also have a dietary sensitivity to something else. Get into the habit of reading ingredients lists.
    • BoiseNic
      Did I outgrow celiac

      By BoiseNic · Posted

      I would avoid gluten at all cost. Sometimes there will be no noticeable damage, but it is still causing an autoimmune response that will manifest in some way or another eventually. Throwing up from a macaroon sounds like something other than celiac disease also.
    • pplewis3d
      Citracal Petite supplements

      By pplewis3d · Posted

      Thanks, Scott! I appreciate you looking that up for me. Perhaps that will be good enough for someone but not for me...super sensitive dermatitis herpetiformis here. I don't take any chances that I can avoid. ~Pam
    • trents
      Did I outgrow celiac

      By trents · Posted

      Welcome to the forum, Liamclarke! We have reports from time to time of people whose celiac disease seems to go into remission. Often, however, it doesn't last. There is also the question of whether or not symptoms or lack of them tell the whole story. Many of us are "silent" celiacs who have very minor or no symptoms when consuming gluten yet slow, insidious damage is still going on in the gut. The only way to tell for sure in your case would be to be retested after going back on gluten for a period of weeks or months such that sufficient time has elapsed for antibody levels in the blood to build up to detectable levels. And I would certainly advise you to do that and not take anything for granted.
×
×
  • Create New...