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5 Htp


covsooze

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covsooze Enthusiast

I've read a little bit about 5 HTP and its benefits for depression and sleep problems and wondering if anyone's got any good / bad experiences of using it. Does it interact with any other meds? (don't know whether I should wait until I'm totally off my ads to try it).


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plantime Contributor

My husband uses it with no problems. He didn't think it was working, but I noticed a difference!

TERESE Rookie
I've read a little bit about 5 HTP and its benefits for depression and sleep problems and wondering if anyone's got any good / bad experiences of using it. Does it interact with any other meds? (don't know whether I should wait until I'm totally off my ads to try it).

I've been taking 50 mgs of 5-HTP every evening for a year now. I had a lot of trouble staying asleep. I also take 1/4 of a 50 mg trazodone so I'm not sure which one is helping but I sleep like a rock now. Slept through a really bad rain storm a few night ago. I haven't had any trouble with 5-HTP.

eleep Enthusiast

I used to take it as a supplement back at a time when I was a bit more of a partyer and doing things that were depleting my body -- it seemed to work wonders for recovery at the time.

sparkles Contributor

What is 5 HTP?

skbird Contributor

I've taken between 25 and 50 mg a day - was fine. I didn't notice it changing my sleep other than more vivid dreams, and I did notice about half the time my mood was improved. I was thinking recently about going on it again.

Since it is a precurser to serotonin and we make nearly half our serotonin in our gut, wouldn't it make sense that it would help a recovering Celiac? Especially with depression.

The only potential issues I've heard of involve taking 5HTP with antidepressants or the triptan migraine pills because they all relate to serotonin issues. I don't know if there is an actual problem taking them together, but something to research for sure, since both of those drugs have an effect on how your body reacts to serotonin - taking a supplement that turns into serotonin might be an issue.

Stephanie

Nancym Enthusiast

I think this is an excellent resource for reading up on supplements: Open Original Shared Link

Open Original Shared Link


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trents Grand Master
I've been taking 50 mgs of 5-HTP every evening for a year now. I had a lot of trouble staying asleep. I also take 1/4 of a 50 mg trazodone so I'm not sure which one is helping but I sleep like a rock now. Slept through a really bad rain storm a few night ago. I haven't had any trouble with 5-HTP.

Terese,

I was Just reading your bio at the bottom of your post. Is your hemoglobin and hematocrit high without the B12 injections? I assume you are taking the B12 injections because you have pernicious anemia.

Steve

utdan Apprentice

I tried it a few years ago and didn't notice any difference, but that was before I went gluten free.

covsooze Enthusiast

Thanks all. Nancy, that link was very useful :) I liked it because it seemd to give a very balanced picture.

TERESE Rookie
Terese,

I was Just reading your bio at the bottom of your post. Is your hemoglobin and hematocrit high without the B12 injections? I assume you are taking the B12 injections because you have pernicious anemia.

Steve

Steve, yes my hemoglobin and hematocrit are high with out the B12 injections and I've just had my blood tested again after being on the B12 for 4 months and it's still high, no change. The dr's note on the test says "probably due to low B12 & B6." I have never been told I have pernicious anemia. Do you have a clue what this means? I see others on the board have pernicious anemia. I always feel like I'm overloaded with questions and answers at the Dr's. I really like her but sometimes feel rushed.

Thanks

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      The body reacts to all grain proteins in all grains from my observation. Call it Gluten, Gliadin, which is what they test for commonly, however, I am Celiac and react with dermatitis herpetiformis to corn and the glutenous protein in it is called Zein. They only test for Gliadin. Testing needs to be updated in my opinion. It only take a small parts per million to continuously create systemic inflammation. This is not productive to healing and all grains contain some for gluten like substance. It's called Molecular Mimicry.
    • Scott Adams
      Thank you for sharing your perspective. It's true that many grains contain proteins that are technically classified as "glutens" (like zein in corn and orzenin in rice), but it's important to clarify that these proteins are not the same as the gluten found in wheat, barley, and rye, which contains gliadin and glutenin. These specific proteins are the ones that trigger an autoimmune response in people with celiac disease. For individuals with celiac disease, the primary concern is avoiding gluten from wheat, barley, and rye, as these are the grains scientifically proven to cause damage to the small intestine. While some people with celiac disease or non-celiac gluten sensitivity may also react to other grains, this is not universal and varies from person to person. For most people with celiac disease, grains like corn and rice are considered safe and are widely recommended as part of a gluten-free diet. That said, you raise an important point about systemic inflammation and individual tolerance. Some people may indeed have sensitivities to other grains or find that eliminating additional grains helps them feel better. However, it’s crucial to differentiate between celiac disease, which requires strict avoidance of wheat, barley, and rye, and other conditions or sensitivities that may involve broader dietary restrictions.
    • trents
      I disagree, Lori. Gluten is a particular protein, not a category of proteins. It is found in wheat, barley and rye. Other cereal grains have proteins that resemble gluten to one degree or another but are not gluten. Gluten is gluten. Avenin is avenin. But yes, it is true, that informally speaking, some have used the term "gluten" to refer to the proteins found in these other cereal grains. It's like the term "kleenex" has come to refer to all facial tissues.
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      In fact ALL grains contain different forms of gluten that go by different names. Corn contains Zein and Rice contains Orzenin. We all need to realize that a very small amount of any of these grains can cause continued systemic inflammation which is not optimal for allowing the body to heal itself.  
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