Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Just Had My Blood Test

JerryK

Recommended Posts

JerryK Community Regular
JerryK
Posted

I think they are running anti-endomysial, the stickers said EMA....

The lab technician seemed to have no idea what test this was.

(freaking rubber band they put on my arm hurt way worse than the needle)

Do you guys think Kaiser knows what they are doing?

I think this is the test that most closely correlates with celiac disease, but I'm not sure. I also think

that Kaiser, to their credit actually is running one of the more expensive tests on me...

Thoughts???

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


chrissy Collaborator
chrissy
Posted

Ttg is the best test, but you also need a total IgA serum done.

JerryK Community Regular
JerryK
Posted
  • Author

I'm pretty sure they are running EMA-IgA which is highly specific for celiac disease. They are probably running some other ones, but EMA was the only thing my rubbernecking could make out...

JerryK Community Regular
JerryK
Posted
  • Author

I base my opinion on documentation like this:

The aim of this work was to establish the diagnostic and follow up value of IgA-class antiendomysium (IgA-EmA) and IgA-class antigliadin (IgA-AGA) antibodies in celiac disease. Correlation with the intestinal histology at the different stages of the disease was evaluated, as well as its therapeutic monitoring ability. Fifty six children, twenty seven girls and twenty nine boys, aged six months to twelve years old, were studied. Thirty nine celiac children were all different diagnostic stages of the disease. Seventeen children with malabsorption symptoms and with normal intestinal histology were used as controls. Sixty blood samples were obtained simultaneously with the small intestinal biopsy. IgA-AGA (ELISA method) and IgA-EmA (immunofluorescent test performed over lower third Rhesus monkey esophagus) were determined in every blood sample. In 34 serum samples from patients with total or subtotal villous atrophy, two were negative for IgA-AGA and only one was negative for IgA-EmA. In 26 samples from patients with normal intestinal histology, two were positive for IgA-AGA and four were positive for IgA-EmA. The results for IgA-EmA had sensitivity 97%, specificity 84.6%, positive predictive value 89.2% and negative predictive value 95%. In the case of IgA-AGA were: sensitivity 94.1% specificity 92.3%, positive predictive value 94.1%, negative predictive value 92.3%. IgA-AGA and IgA-EmA showed a high correlation with intestinal histology and are in combination powerful tools for the diagnosis and follow up of celiac patients. Besides, they provide a useful aid in the indication of a jejunal biopsy and in close monitoring of the dietary treatment compliance

JerryK Community Regular
JerryK
Posted
  • Author

Also, I gotta admit...I'm really nervous about this now. If this comes out positive, there will be no

more denial.

I feel like I'm having a baby:)

happygirl Collaborator
happygirl
Posted

You want tTG and EMA, and then other pluses include Total Serum IgA, Antigliadin IgA and IgG

Nancym Enthusiast
Nancym
Posted
Also, I gotta admit...I'm really nervous about this now. If this comes out positive, there will be no

more denial.

I feel like I'm having a baby:)

You've been gluten-free though right? What're you going to do if you're negative?

Ha! From my understanding having a baby hurts more than a tourniqette on the arm!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


jerseyangel Proficient
jerseyangel
Posted
Ha! From my understanding having a baby hurts more than a tourniqette on the arm!

You are right about that! :P

Good luck, Jerry--and try not to be nervous. I mean, you already know exactly how gluten affects you and how you feel so much better off of it.

A set of numbers won't change that. ;)

JerryK Community Regular
JerryK
Posted
  • Author
You've been gluten-free though right? What're you going to do if you're negative?

Ha! From my understanding having a baby hurts more than a tourniqette on the arm!

Well, I haven't been gluten-free for about a month. Even if it's negative I'm going to go gluten-free, I feel better.

Lisa Mentor
Lisa
Posted
Well, I haven't been gluten-free for about a month. Even if it's negative I'm going to go gluten-free, I feel better.

APPLAUSE...coming from my house!

JerryK Community Regular
JerryK
Posted
  • Author

Difficult to guess whether I'm going to test positive or not....

If I were a betting man, I wouldn't touch this one...I honestly don't know.

rez Apprentice
rez
Posted

I totally agree w/ Chrissy, you should have had the tTG. The EMA is very specific to Celiac, but not very sensitive. Meaning, if you're positive, it's definitely Celiac, but if negative there's a good chance it could be false negative. The sensitivity of the EMA is no where close to that of the tTG. The two main tests you should have had run are the tTG and the total IgA. You need to know if you are IgA deficient. If you are, the tTG and EMA won't mean anything. I would call your doc and have him add the tTG and total IgA.

rez Apprentice
rez
Posted

Go to the Chicago Celiac Research website for good accurate info. It also talks about the Celiac screen. Good luck!

chocolatelover Contributor
chocolatelover
Posted

Jerry, you're such a good person to have on this board--I have learned a lot from you and the responses of others. Hopefully you will get the results before you leave for your cruise (lucky devil!). In any case, at least you are wise enough to know what makes you feel good!

Thanks for asking the questions about the blood test. I just got a copy of my "celiac panel" blood work, and all they did was IGA and TTG. I thought there was more to it than that? My numbers also don't seem to make any sense. Oh well...I'm still waiting for the biopsy results and I'm fairly certain that I'll be giving enterolab my business by this time next week.

Jerry, I wish you the best. I feel a bit of a kindrid spirit with you as I am going through much of the same as you--you just are able to write about it and I simply read most of the time.

cl

jerseyangel Proficient
jerseyangel
Posted

Here is the Celiac Panel--they should run all of the tests

Anti-Gliadin (AGA) IgA

Anti-Gliadin (AGA) IgG

Anti-Endomysial (EMA) IgA

Anti-Tissue Transglutaminase (tTG) IgA

Total Serum IgA

chocolatelover Contributor
chocolatelover
Posted

Do you know what the numbers are supposed to be?

chrissy Collaborator
chrissy
Posted

the EMA test is left up the the interpretation of the one running the test which can make it less accurate. the Ttg test is done differently so there is no room for human error. this is why it is a better test.

rez Apprentice
rez
Posted

the labs levels vary. they all have different ranges.

rez Apprentice
rez
Posted
Jerry, you're such a good person to have on this board--I have learned a lot from you and the responses of others. Hopefully you will get the results before you leave for your cruise (lucky devil!). In any case, at least you are wise enough to know what makes you feel good!

Thanks for asking the questions about the blood test. I just got a copy of my "celiac panel" blood work, and all they did was IGA and TTG. I thought there was more to it than that? My numbers also don't seem to make any sense. Oh well...I'm still waiting for the biopsy results and I'm fairly certain that I'll be giving enterolab my business by this time next week.

Jerry, I wish you the best. I feel a bit of a kindrid spirit with you as I am going through much of the same as you--you just are able to write about it and I simply read most of the time.

cl

was your tTG positive?

chocolatelover Contributor
chocolatelover
Posted

No, but I had been off gluten for a while when they did the test. I'm one of those that has many symptoms but my bloodwork was negative. I have been diagnosed with lymphocytic colitis, which hasd been linked to celiac. It's also an autoimmune disease and they think that it's the same genes cause both disorders. Dr. Fine (Enterolab) feels that gluten sensitivity may be caused by the colitis, which results in negative blood tests because the blood tests are just not sensitive enough to pick it up if you are not a full-blown celiac. What I don't know is whether the gluten sensitivity would disappear once the colitis is treated. It's all very frustrating!

JerryK Community Regular
JerryK
Posted
  • Author
Here is the Celiac Panel--they should run all of the tests

Anti-Gliadin (AGA) IgA

Anti-Gliadin (AGA) IgG

Anti-Endomysial (EMA) IgA

Anti-Tissue Transglutaminase (tTG) IgA

Total Serum IgA

Thanks, they may be running others besides the EMA, that's the one I picked up on. Wish I knew how long it was going to take!!

JerryK Community Regular
JerryK
Posted
  • Author
Thanks, they may be running others besides the EMA, that's the one I picked up on. Wish I knew how long it was going to take!!

I will feel like an outcast if both my gene test and Celiac Panel come out negative :rolleyes:

chocolatelover Contributor
chocolatelover
Posted

Do you feel like this is consuming your life? I feel like every moment is spent thinking about the results, wishing they were faster, thinking about what can I eat that won't make me feel like sh$%, what DID I eat that made me feel like sh$%, trying to get answers to questions that no one knows, thinking about whether I should switch doctors, and on and on and on...

jerseyangel Proficient
jerseyangel
Posted
I will feel like an outcast if both my gene test and Celiac Panel come out negative :rolleyes:

Nah--you're already "one of the family" :D

No matter what the tests say, you're part of the gluten-free crowd. Kind of a dubious honor..... :P

JerryK Community Regular
JerryK
Posted
  • Author
Do you feel like this is consuming your life? I feel like every moment is spent thinking about the results, wishing they were faster, thinking about what can I eat that won't make me feel like sh$%, what DID I eat that made me feel like sh$%, trying to get answers to questions that no one knows, thinking about whether I should switch doctors, and on and on and on...

Absolutely I can relate to that feeling. Especially when I was forcing myself to eat stuff that I know is

going to give me the runs or make me feel horrible. At some point you have to just let it go and do the best that you can do. I've done what I can do, I've had Enterolab testing, I have gene testing and a Celiac panel queued up. I've done due diligence....I now need to let it go and get on with life.

The Celiac diet is a pain in the a$$ to be honest, only because it isn't convenient. It doesn

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      127,111
    • Most Online (within 30 mins)
      7,748
    Andy Barak
    Newest Member
    Andy Barak
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      69.9k
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Soleihey
      Gluten Ataxia and Malabsorption

      By Soleihey · Posted

      I have been on supplementation for almost 11 months with no deficiencies showing up on blood work. So was just hoping to hear someone else’s story where it took longer to heal. 
    • Erain
      Orgain Protein Powder

      By Erain · Posted

      Here’s the answer from the company 😊   Hi Emily,    Thank you for reaching out to us! We can confirm the Organic Protein + 50 Superfoods Powder is gluten free. The organic barley and wheatgrasses we use are harvested prior to jointing, before the grain forms and any gluten protein is present. Rest assured appropriate measures are taken to ensure our gluten free products comply with the FDA final rule to be labeled as gluten free, as claimed on the side-panel label. Our suppliers are required to verify each ingredient and in order to ensure that our gluten free products comply with the FDA requirements, our manufacturing facilities use the ELISA test method to confirm gluten levels are less than the standard limit of <20 ppm.    If you have allergy concerns about consuming the grasses, we recommend consulting further with your healthcare provider. I hope this information helps! Please let us know if you have other questions.   
    • Erain
      Orgain Protein Powder

      By Erain · Posted

      That’s great to know. Thanks Scott
    • trents
      Postponing seeking a diagnosis?

      By trents · Posted

      Welcome to the forum, @kim-d! Recently revised guidelines or the "gluten challenge" recommends the daily consumption of at least 10g of gluten for at least two weeks up until the day of the antibody test blood draw. 10g of gluten is the amount found in about 4-6 slices of wheat bread. IMO, I would wait until you have time to do it right so as to remove all doubt as to whether or not your gluten consumption was adequate for long enough to ensure valid testing. In the meantime, focus on removing gluten from your diet and see how your symptoms improve (or not) as one piece of the diagnostic puzzle.
    • kim-d
      Postponing seeking a diagnosis?

      By kim-d · Posted

      Hello. I'm a 22 year old college student and I've had constant stomach problems since I was 14. Recently I noticed that my problems get worse when I eat more wheat. I tried to follow a gluten free diet, which didn't end up entirely gluten free, but I still had reduced my gluten consumption very much, and I felt a lot better. I also have fatigue, inability to gain any weight, iron deficiency, possible vitamin deficiencies, really bad memory and brain fog that increases by time, unexplainable muscle aches and tachycardia which all can possibly explained by celiac/NCGS.  I wasn't able to continue a completely gluten free diet as I am eating from my school and dorm's cafeteria and almost all food there have gluten so I was going very hungry. They do offer a gluten free menu with a report though. So I decided I should try getting a diagnosis if I can, especially after reading how it was much harder to do gluten challenge after quitting gluten for a while. I was able to get an appointment for next week, and started eating around 150gr of bread per day to be sure.  First 24 hours I didn't feel any worse so I was starting to doubt myself, but then bloating hit hard. It wasn't anything unbearable, but the problem is I have finals soon and I'm now realizing this is a really bad time to do this. I can't begin studying from pain distracting me. I'm thinking of cancelling the appointment and eat low gluten until exams are over.  I worry about one thing. Before I went low gluten, I was eating a lot of bread already for over a month, which is what clued me into gluten, and I only went low gluten for around 10 days before going high gluten again. I wasn't that worried about a false negative. But if I eat low gluten until my exams are over, it means over a month of low gluten, and I would need a lot more time eating high gluten later to get a correct result.  I'm not sure which one should I do, bear it until my appointment or cancel it and try again when I'm free later. And If I choose the second one, how long would I need to do the gluten challenge for a blood test?
×
×
  • Create New...