Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Genetic Testing - Double Dq8 - Anyone Else Have The Double?

GFinMN

Recommended Posts

GFinMN Apprentice
GFinMN
Posted

just got my genetic test results back from the mayo clinic. double DQ8. the doc thinks that is causing me to be an extremely sensitive celiac, more than most. does anyone else have the double? does it really make a difference? i'm new to this genetic stuff and don't totally understand it.

thanks.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


gfpaperdoll Rookie
gfpaperdoll
Posted

oh wow, I have never heard of anyone being double DQ8. Most people seem to have a DQ2 & a DQ8 or DQ2 & a DQ1, or DQ8 & DQ3, etc, in other words either one of the gluten genes & one of the gluten intolerant genes, or one of each of the gluten genes, or two gluten intolerant genes.

Those of us that are double DQ1, know that it is a bummer with a lot of neurological stuff & additional food intolerances/allergies... Most double DQ1 people I know also cannot tolerate dairy. I cannot tolerate grains...

I recently read a post by someone that was double DQ2 & it seems that they had it very bad also.

I wonder if it is having the two copies of the same gene that is so bad?????

Would you mind giving us a list of your health issues?...

ravenwoodglass Mentor
ravenwoodglass
Posted

I am the only one in my family to have the gene test. I am not a DQ8 but am a double DQ9. In my case that double dose did seem to lead to more sensitivity than most. I would imagine a double of any gene would cause an increased sensitivity to what ever that gene predisposes us to.

GFinMN Apprentice
GFinMN
Posted
  • Author

yeah, i seemed to be A LOT sicker than any of the other celiacs i know. mine came on very suddenly. within one week i had tingling in hands and feet, pins and needles over entire body, unable to swallow food, major nausea. this was pre-diagnosis. first they thought i had MS or some neurological disorder, then ruled all that stuff out and finally found celiac thanks to gastro doctor. i also developed a major limp in my right leg. thankfully, all the neuro symptoms went away once i went gluten-free. however, i have been at the mayo clinic cause my stomach isn't healing and i have developed reactive-hypoglycemia. that's when the doc discovered the double DQ8. i am VERY strict with diet - don't eat out, no cross contamination, checked all hair and beauty products, yet my intestine is still inflammed according to the mayo. the doc said he has seen this happen in people with the double gene.

gfpaperdoll Rookie
gfpaperdoll
Posted

gluten-free in MN, you might need to try going dairy free also, & for a time grain free, you might be able to add some things in later. But for now, I would play it totally safe & not eat any grains. I would also not eat soy, no one needs soy. No artificial sugar. just rethink everything that you are eating. I think that you can still get some great meals with a limited diet of meat, seafood, veggies, fruits & nuts. maybe eggs if you do not have a problem with eggs.

I know that it is difficult to change your eating habits but the rewards are so worth it.

I know you will be better soon...

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      127,601
    • Most Online (within 30 mins)
      7,748
    Namahoe
    Newest Member
    Namahoe
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      70.3k
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • trents
      Type 1 diabetes (4year old) and positieve ttg

      By trents · Posted

      Welcome to the forum, @marinke! "Type 1a diabetes (DM1) is associated with an increased risk of celiac disease (celiac disease) (1)." from: https://diabetesjournals.org/care/article/35/10/2083/38503/IgA-Anti-transglutaminase-Autoantibodies-at-Type-1 "The prevalence of celiac disease (celiac disease) in children with type 1 diabetes (T1D) is 5.1%, and it is often asymptomatic (1)." from: https://diabetesjournals.org/care/article/48/2/e13/157637/Diagnostic-Outcomes-of-Elevated-Transglutaminase So, this is 5x the rate found in the general population.
    • Mari
      Long term recovery

      By Mari · Posted

      Hi James47, You are less than 2 years into your recovery from Celiacs.  Tell us more about the problems you are having. Do you just want to get rid of belly fat or are you still having symptoms like gas and bloating.    For symptoms you may need to change your diet and take various supplements that you cannot adsorb from the foods you eat because of the damage caused by the autoimmune reaction in your small intestine. 
    • marinke
      Type 1 diabetes (4year old) and positieve ttg

      By marinke · Posted

      My daughter (4 years old) has type 1 diabetes since she was 1. Therefore, every year a screening is done. We live in the Netherlands. Every year the screening was fine. This year here ttg is positive, 14, >7 is positive. IGA was in range. Could the diabetes cause this positive result? Or the fact that she was sick the weeks before the brood test?
    • Baz
      Shortness Of Breath (the "sighs")?

      By Baz · Posted

      @DayaInTheSun what were the shortness of breath symptoms for you ? And did they come on all of a sudden or was it a gradual increase in said symptoms?
    • DayaInTheSun
      Shortness Of Breath (the "sighs")?

      By DayaInTheSun · Posted

      I had shortness of breath so much so I went to a lung doctor. I told him I get short of breath wirh certain foods, he said “Food doesn’t affect hour breathing.” I told him maybe it was an allergy  he cut me off then said “Food allergies don’t cause shortness of breathe.” I beg to differ as soon as I figured out what foods were causing my shortness of breath it went away. I also never saw him again as he was rude, condescending? And refuse to listen to me kept dismissing my problems as “you’re young.” I cut out Soy, dairy, sesame, eggs, and of course gluten. I stopped being short of breath, going on a two years now. No thanks to the doctor I saw. Figured it out on my own.   
×
×
  • Create New...