Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Flattened Villi


Sandi*

Recommended Posts

Sandi* Apprentice

OK, I've been doing some reading and I'm confused. I've come across the idea that flattened villi doesn't necessarily mean that that person has celiac. But what else would it be?

What sparked my curiosity was Open Original Shared Link by tired47. It states:

"Hi! I had the camera pill test done. My results were flattened villa and erosions of small bowel. I had blood work, and biospy which were all negative. Dr. has said he does not think it is celiac/crohn's. I am following the gluten free diet as advised. My family Dr. said it would help "heal" my small bowel. And I am still having severe malabsorption issues... we know it comes from small bowel abnormalities, but why do it have them??? Ideas anyone??? ( I was on mega doses of antibiiotics for H pylori last year)."

I don't understand how can your villi be flattened and yet your doctor would say it's not celiac. What else would it be?


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



cruelshoes Enthusiast

Celiac is the main cause for villi damage, but there are other causes. Some of the other possibilities rarely cause flatened villi, and are usually found in conjunction with Celiac Disease or immuno-deficiencies.

Villi damage can be caused by:

Coeliac Disease

Cows Milk Protein Intolerance

Soy Protein Intolerance

refractory Sprue

Collagenous Sprue

Immunodefiency Synodromes

Mediterranean lymphoma

intestinal ulceration

Gastroenteritis

Intractable Diarrhoea of Infancy

Protein Calorie Malnutrition

Kwashiorkor

Tropical Sprue

Parasitic Disease:

Giardiasis

Strongyloidiasis

Coccidiosis

Intestinal Capillariasis

Hookworm Disease

Eosinophilic Gastroenteritis

Contaminated bowel Syndrome

Drug and Radiation Damage

Source: https://www.celiac.com/articles/50/1/Main-C...illi/Page1.html

Hope this helps.

Sandi* Apprentice

Thanks a lot! :D

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      127,524
    • Most Online (within 30 mins)
      7,748

    Rob71
    Newest Member
    Rob71
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      70.2k

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • trents
      "Bonus points". I like that analogy!  At this point, the following article might be helpful: Eating out will be the biggest challenge and will present the most threat to avoiding gluten since you don't have control over how food is prepared and handled back in the restaurant kitchen. Become comfortable with asking questions of restaurant staff and requesting that your food be cooked in clean pots/pans/surfaces that haven't been used for gluten containing foods since last washed. In time, you will become more comfortable with taking control in these situations and learn to be appropriately assertive. One thing that will take time for you to get a handle on is how sensitive you are to minor amounts of gluten such as you might get in cross contamination scenarios. Each of us is different in that sense and there is no substitute for personal experience. When in doubt, however, avoid foods that you feel may be significantly cross contaminated. Better safe than sorry. In time, you will develop a sixth sense about these things.
    • Lynnard
      Thank you!  Yes - labs are above but Deamidated Gliadin was super high, tTG was a weak positive and Immunoglobulin A was way below normal which gives "bonus points" to the positive tests because it can also cause false negative results.  This information confirms my thinking and I really appreciate your feedback!!!  
    • trents
      By far, the most likely cause of villous atrophy in the Marsh 3 range is celiac disease but there are other possible causes. Did you also have positive antibody tests? My guess is that when you see your physician he/she will declare you to have celiac disease. Of course, the ultimate proof of the pudding will be if you experience definite improvement in symptoms after going gluten free which, since you have now completed testing, you should begin to do.  
    • Lynnard
      Hi again - I received the biopsy results but haven't had follow up appointment with Dr. yet.  Wondering if you could comment on this: "Duodenum, random, Biopsy (Cold Forceps): MILD VILLOUS BLUNTING WITH PROMINENT INTRAEPITHELIAL LYMPHOCYTES, CONSISTENT WITH SPRUE (MARSH TYPE 3A). See Comment. Negative for Infectious Organisms, Dysplasia or Malignancy. COMMENT: While characteristic, the histologic findings are not diagnostic for gluten-sensitive enteropathy / celiac disease. A number of additional entities can enter into the differential diagnosis of celiac disease based on the histologic features, including tropical sprue, bacterial overgrowth / stasis, unclassified sprue, specific food allergies, many drugs including NSAIDs, olmesartan and immune checkpoint inhibitors, and a wide range of autoimmune diseases including adult-onset autoimmune enteropathy, diabetes, thyroiditis, lupus and multiple sclerosis and occasionally common variable immune deficiency. History of drug take, celiac serologies, HLA-DQ status and response to a gluten-free diet might be a key for a definitive diagnosis" They say "consistent with Sprue (Marsh Type 3A)" and then comment that the findings are not diagnostic for celiac disease.  I thought Marsh type 3 was conclusive (and I know that 3A is the best outcome as it relates to intestinal damage). Is this just normal caveat language or am I missing something?  I had appt scheduled for tomorrow but Dr. is sick and now rescheduled to over a week from now.  Appreciate any insight you can offer in the mean time.  Thanks!!
    • Sicilygirl
      Hello Scott, I did lose weight at the beginning of diagnosis and I know that it will take time to put on the weight I did lose. I think I have no appetite because this has been a roller coaster of emotions and a Big change on my body and its out of whack mentally and pysically. I think I am just depressed to be honest.  
×
×
  • Create New...