Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Help With Cd Link To Schizophrenia


PsyDbound

Recommended Posts

PsyDbound Newbie

I am currently doing reserch on gut permibility and shizophrenia.I don't quite understand the celular process after penetration of the mucosa. I would appriciate any help in getting a clear picture of the transition from anti-gliden to abnormality of the t-cell and the brain connection. Please keep in mind that I am Psych trained and not medical.

Thanks for you time,

Christina


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



MySuicidalTurtle Enthusiast

I hate to seem daft, but I think you would get more help by explaining what you need in other words.

PsyDbound Newbie

Sorry, my bad. Im just having a hard time with the physiology of celiac disease after it has damaged the villi. I know that malabsorbtion is a problem but I don't understand what is being tranfered past the gut wall to the t-cells and what they have to do with schizophrenia. I am sorry if this isn't clear but I really dont understand it myself. Also, if I have misunderstood the whole villi breaking part please correct me.

Thanks,

Christina

Carriefaith Enthusiast

I have read in the book Wheat Free Worry free: The Art of Happy, Healthy Gluten-Free Living by Danna Korn that celiac and schizophrenia may be related. I believe that there is a section in the book on this topic.

MySuicidalTurtle Enthusiast

I never thought about the two being connected but I can see how they could be, along with other disorders. Very interesting stuff.

FaithInScienceToo Contributor

Quick reply...

Here is a link for a the discussion of this topic - There are numerous references contained in it - perhaps there is something there for you?

Open Original Shared Link

Good luck,

Gina

PsyDbound Newbie

Thanks for the info, its great and coincides with what I have been researching. I think I may need to confer with a physiologist because I still don't understand what happens on a cellular level. Is seems quite confusing.

Thanks again,

Christina


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Maggie1956 Rookie

Hmmmm, very interesting. <_< My sister is a schizophrenic, and she also has trouble in her gut. She recently tested negative to celiac, but I still think she may be gluten intolerant. I'm not sure how accurate the test was either.

Give us an update when you find out more.

mommida Enthusiast

Have you looked into the studies that show calcifications of the brain in Celiac patients?

  • 2 weeks later...
Guest BellyTimber

As a parallel to this may I suggest Paul Shattock, Paul Whiteley and Dawn Savery who have published the following titles about their work at the Autism Research Unit, School of Health Sciences, University of Sunderland, Sunderland, SR2 7EE, U.K.:

- Autism as a metabolic disorder: guidelines for gluten and casein free dietary intervention

- Autism as a metabolic disorder

- Guidelines for the implementation of a gluten and/or casein free diet with people with autism or associated spectrum disorders

I would be surprised if you didn't find the biochemistry mentioned in these of some interest.

Let us know how you get on - we'll try to follow your terminology!

Michael

Ruth UK Newbie

Michael,

I am honestly NOT stalking you. It's just that it's great to have someone from the UK here who is obviously very well read! May I be cheeky enough to enquire what your profession is? (Obviously, don't reply to this if you don't wish to.)

I may have already mentioned this in another post to you, but my lad has ADHD, Asperger's Syndrome and dyspraxia, and in connection with this I would agree with you that the work taking place at the ARU is VERY interesting. My son tested +ve on their tests for 'gluten and casein insensitivity'.

No doubt will speak to you again:)

LUAP Newbie

THE ANSWER FOR THE GUT PERMEABILITY IS GIVEN BY DOUG KAUFMANN IN THE FUNGUS LINK.

I HAVE'NT READ ANYWHERE THAT THERE WAS ABNORMALITY WITH T CELLS...T CELLS ARE PRESENT WHEN SOMETHING DANGEROUS IS PRESENT...

LET TALK ABOUT GLIADIN (MEMBER OF THE GLUTEN GROUP).

THE PEPTID THEORY SAYS THAT THE PROBLEM WITH GLUTEN IS THE SIZE OF THE PROTEIN. THE VERY LONG AMINO ACID CHAIN. RESEARCH ARE CONDUCT ON ENZYMES THAT COULD HELP BREAK THAT HEAVY AMINO ACID CHAIN.

THE PROBLEM WITH THE LONG CHAIN...THE LONGEST IT IS, THE MORE THERE IS GLUTAMIC ACID.

GLUTAMINE, MSG, GLUTAMIC ACID...NATURALY PRESENT IN FOOD. GRAINS CONTAINS ALOT OF IT, ALONG WITH TOMATOES, BEETS, AND OTHERS.

REFERS TO THE BOOK: EXCITOTOXINS, THE TASTE THAT KILLS.

IN THOSES 2 BOOKS, YOU HAVE ALL THE ANSWER YOU NEED...IN MY OPINION.

PAUL

PsyDbound Newbie

Thank you so much for all of your help and support. I am now completing my research and will post a link to my findings. Again, you have all been so helpful.

FYI I have a Mom, 3 sisters and a brother all with celiac disease (thats out of 12 kids and not all have been tested yet). After writing this research I am convinced testing for celiac disease should be universially accepted and preformed before age five.

Thanks,

Christina

PsyDbound Newbie

I finished my research and would be happy to e-mail my findings and refrences. Below is a link to a very significant study by William Eaton for the British Medical Journal.

Thanks again for all the great ideas!

Christina

Open Original Shared Link

Guest BellyTimber

Ruth

Didn't think you were.

Not working in any related field.

Over the decades my body has talked to me bit by bit about neurology and metabolism leading me to other sources of information. The spirit leading through the body. Making better sense of my life history (so far).

I get little pieces or batches of thoughts together & can express them all in one but the general skill of information organising comes very difficult to me, a kind of dyslexia I think. My having hyperfocussed on words since an early age and excellent spelling and handwriting masked that to "experts"!

Despite so much of my life being behind me fortunately I still have my life ahead of me in some tantalisingly unknown ways...

Michael

:P

Guest BellyTimber

Paul,

The various causes and effects of diseases are like one of those gangs that put forward a different "suspect" every time one goes to pursue ones "enquiries" among them.

(probably not a good metaphor)

Regards

Michael

judy05 Apprentice

Michael,

When you mentioned "dyslexia" a little "bell" went off in my head. In preparing for

my thyroidectomy my endo doc gave me a book to read about endocrine diseases in which the author, a doctor from New York City, explained about a syndrome, group of diseases, which seem to occur in many individuals. It seems when one organ fails, such as the pancreas, diabetes occur. This in turn leads to another endocrine failure, such as thyroiditis or Grave's disease. His point was that these diseases are all related. Some other related diseases were Celiac, Dyslexia, and

prematurely gray hair?? I wish I could remember the title or the author, I lent it to

someone and never got it back. It seems to be true because my family has each

examples of each one of these.

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      127,726
    • Most Online (within 30 mins)
      7,748

    Holly B
    Newest Member
    Holly B
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      70.4k

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Marie70
      Wow!! Scott, Trent and Christiana thank you so much for your fast replies!! The information you have shared with me has helped me tremendously.   Thank you for all the articles.  I appreciate you all so much!! I’ll keep you posted in this post.  I will encourage her to get tested.  I feel a little better!
    • DayaInTheSun
      It was gradual, just not being able to catch my breathe like I always had to take a deep breathe even taking a few steps I would be winded.
    • cristiana
      Hi Marie Welcome to the forum. I am so sorry your daughter is pointing the finger at you like this.   I am afraid children of any age can be very cruel to their parents - I certainly look back at some of the things I said to my mother and father in the past, and wish I could unsay them.  Sometimes people just need a safe place to vent, and unfortunately having a go at one's parents is the all too easy option.  If she is anything like me, she will regret what she says one day.  (Oh... if only I had the chance rewind the clock!) I just wanted to add one more thing to Trent's and Scott's excellent posts and that is regarding diet:  I have to say, not one person  (my nutritionist, my gastroenterologist or GP) has EVER suggested that a poor diet was the cause of my coeliac disease.    In all the various clinics I have attended these past nearly 12 years no-one has ever asked if I was brought up on processed food, or questioned if I eat 5 fruit and veg a day.  Sure, unfortunately I am only too well aware that I could do a lot better with my diet and it's a constant challenge for me not to give into what I like (unfortunately I've always had a sweet tooth).   But I know some super healthy 10 fruit and veg a day types who still got coeliac disease, and equally, a lot of people who eat all the wrong stuff and they still have cast iron stomachs. Do encourage her to get checked though - it may be that she hasn't got coeliac disease at all. Come back to us if you need any more support through the process. Cristiana
    • trents
      Welcome to the forum, @Marie70! The first thing to know is that celiac disease has a genetic base. The two main genes that have been identified as providing the potential to develop celiac disease are HLA-DQ2 and HLA-DQ8. About 40% of  the general population carries one or both of these genes. However, only about 1% of the general population ever develops celiac disease. So, we know that in addition to possessing the genetic potential to develop celiac disease, there has to be some triggering environmental or medical "stress" factor (or factors) that switches the gene or genes on such that they are awakened from their latent condition and become active. What may be the triggering factor (or factors) is the subject of much debate. Here is an article that discusses this subject: Second, what will your daughter have to say if her testing for celiac disease is negative? She may have to add crow to her diet. Third, and this is what I really want to focus on because my wife and I are dealing with something similar in our relationship with our own adult daughter: the real problem is not whatever shortcomings you, as the family cook, may have had when providing meals, the real problem is with your daughter's heart/soul/attitude. If it turns out to be true that she has celiac disease, it is likely she would have developed the condition sooner or later even if her diet had been healthier while growing up. She is angry about the prospect of having to deal with the dietary and social limitations that having celiac disease would impose upon her. She doesn't want to face up to the fact that this may be a new reality that will dramatically changer her life and she is looking for someone or something to blame. And she has conveniently turned her wrath on you rather than saying to herself, "Okay, this is what it is. Now what can I do to make adjustments in order to with it the best way I can?"  When faced with a life-changing reality, people will either accept it for what it is, make adjustments and move on or they will become angry and look for something or someone to blame and get stuck. For now, at least, your daughter has chosen the latter option. Don't let her problem destroy both of you.
    • Scott Adams
      It sounds like you’re carrying a lot of guilt, but please know that you didn’t cause your daughter’s potential celiac disease or your son’s Crohn’s. These conditions have strong genetic components, and while diet can influence symptoms, it does not cause autoimmune diseases. You did the best you could with the knowledge you had at the time, and no parent is perfect. Your daughter’s frustration is understandable, but it’s likely coming from a place of fear and uncertainty rather than true blame. Let her get tested, and if she does have celiac disease, you can support her moving forward. Instead of focusing on guilt, try shifting the conversation toward healing and learning together. You’re not alone, and you don’t deserve to carry this weight on your own. This article might be helpful. She needs to be screened for celiac disease before she can be sure that she has it. Another approach not discussed in the article is a genetic test for celiac disease, which she could do without eating gluten.      
×
×
  • Create New...