Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Targeted Amino Acid Therapy


rock on

Recommended Posts

rock on Apprentice

Hi all!

It's been a long time since I've posted. For those of you who don't know me, I'm often here inquiring about things for my husband.

Anywho, he's been on a strict gluten free diet for over a year now for several reasons, but the main one being psoriatic arthritis.

He has gone off of his methotrexate (about 4 mos ago) and has been feeling relatively ok, except for some aches & pains here & there. His psoriasis is very mild & not having to take the pills has greatly improved his quality of life.

But, a new problem has arisen pretty severely over the last few months regarding anxiety, some depression & bad anxiety attacks.

An internist prescribed him ativan which has helped quite a bit, but we know isn't an answer to his problems.

A psychiatrist rx'd an antidepressant & a stronger anti-anxiety pill which my hubby hasn't filled the prescription for because he's nervous that taking those could cause another ride down a slippery slope.

Just yesterday we saw a D.O. & for the first time ever felt like we found a doctor who would actually listen...who actually cared about all of the issues that we feel are pertinent to my husband's medical history & who gave some hope to us that he could help my hubby get himself onto a track of health rather than simply masking all his various symptoms with pharmaceuticals. He sat with us for over 2 hours & really got specific about things that other doctors just wrote off. We are hopeful.

The first thing that he wants to do with my husband is start him on a Targeted Amino Acid Therapy to help to stabilize his neurotransmitters.

I've done some research & it seems to make sense (especially concerning my hubby's medical history)....but, I figured I would post here to see if any of you fine folks have had personal experiences with it or have known anyone who has tried the therapy.

As always, I thank you in advance for any info you all may be able to provide for us in our trek toward health for hubby (& our relationship!!)

Best~

RO


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Cinnamon Apprentice

I have a son with ADHD and dyspraxia, both of which are problems with dopamine in certain areas of the brain. I tried giving him tyrosine to boost his dopamine, and it worked amazingly well for a few days, then stopped working.

I tried giving him a higher dose, and that worked for another day or two, then stopped working. I was afraid to increase the dose any more, so I took him to the doctor, and this is what he told me. He said the brain is an amazing thing, it constantly monitors what comes in and makes adjustments accordingly. If you keep on giving it a high dose of only certain amino acids, it will make adjustments in order to dump it. But he said it depends on the plasticity of the person's brain. He said he's seen it work in a few adults, but not many. And he said it will never work in a child because their brains are so very plastic, constantly adjusting and changing.

It's worth a try, though. You never know, it might work and continue to work depending on the plasticity of his brain, which is less in adults. It sure did work for my son for those few days. Nothing including ADHD medication or gluten-free diet did as much to alleviate these problems.

I hope it works for you!

rock on Apprentice

Thanks Cinnamon. That's interesting that tyrosine helped him (even if it was for short periods).

I am certainly hopeful that this helps my guy. He's on the 2nd day of treatment...and treatment includes several types of amino acids in varying doses throughout the day.

We'll see. He says that he can feel that something is happening. He had some GI upset from it yesterday & the doctor lowered the dosage. He seems to be doing a little better today.

Perhaps something more comprehensive in an amino acid approach could help your son. So many things in our bodies rely on synergy...so many vitamins and minerals need to be balanced, so it figures that you should have to balance amino acids too.

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - trents replied to Atl222's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      1

      Increased intraepithelial lymphocytes after 10 yrs gluten-free

    2. - Scott Adams replied to Aretaeus Cappadocia's topic in Gluten-Free Foods, Products, Shopping & Medications
      1

      Brown Rice Vinegar (organic) from Eden Foods is likely gluten free

    3. - Scott Adams replied to wellthatsfun's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      1

      nothing has changed

    4. - Scott Adams commented on knitty kitty's blog entry in Thiamine Thiamine Thiamine
      1

      About Celiac Remission

    5. - Scott Adams replied to TheDHhurts's topic in Gluten-Free Foods, Products, Shopping & Medications
      2

      need help understanding testing result for Naked Nutrition Creatine please

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,190
    • Most Online (within 30 mins)
      7,748

    Atl222
    Newest Member
    Atl222
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • trents
      Welcome to the celiac.com community, @Atl222! Yes, your increased lymphocytes could be in response to oats or it could possibly be cross contamination from gluten that is getting into your diet from some unexpected source but not enough to damage the villi. And I'm certain that increased lymphocytes can be caused by other things besides celiac disease or gluten/oats exposure. See attachment. But you might try eliminating oats to start with and possibly dairy for a few months and then seek another endoscopy/biopsy to see if there was a reduction in lymphocyte counts. 
    • Scott Adams
      This is a solid, well-reasoned approach. You’re right that “koji” by itself doesn’t indicate gluten status, and the risk really does come down to which grain is used to culture it. The fact that you directly contacted Eden Foods and received a clear statement that their koji is made from rice only, with no wheat or barley, is meaningful due diligence—especially since Eden has a long-standing reputation for transparency. While the lack of gluten labeling can understandably give pause, manufacturer confirmation like this is often what people rely on for traditionally fermented products. As always, trusting your body after trying it is reasonable, but based on the information you gathered, your conclusion makes sense.
    • Scott Adams
      Seven months can still be early in celiac healing, especially if you were mostly asymptomatic to begin with—symptoms like low iron, vitamin D deficiency, nail changes, and hair issues often take much longer to improve because the gut needs time to recover before absorption normalizes. A tTG-IgA of 69 is not “low” in terms of immune activity, and it can take 12–24 months (sometimes longer) for antibodies and the intestinal lining to fully heal, particularly in teens and young adults. Eating gluten again to “test” things isn’t recommended and won’t give you clear answers—it’s far more likely to cause harm than clarity. Weight not changing is also very common in celiac and doesn’t rule anything out. Please know that your frustration and sadness matter; this adjustment is hard, and feeling stuck can really affect mental health. You deserve support, and if you can, reaching out to a GI dietitian or mental health professional familiar with chronic illness could really help you through this phase. This study indicates that a majority of celiacs don't recover until 5 years after diagnosis and starting a gluten-free diet: Mucosal recovery and mortality in adults with celiac disease after treatment with a gluten-free diet However, it's also possible that what the study really shows is the difficulty in maintaining a 100% gluten-free diet. I suspect that if you looked closely at the diets of those who did not recover within 2 years might be that their diets were not 100% gluten-free. Perhaps they ate out more often, or didn't understand all of the hidden ingredients where gluten can hide. Either way, it shows how difficult recovery from celiac disease can be for most people. According to this study: This article explores other causes of flattened villi:    
    • Scott Adams
      Gluten testing is normally reported in ppm (parts per million), which is equivalent to mg/kg, not micrograms by itself. A result of <0.025 mcg only becomes meaningful if you know the sample size tested (for example, mcg per gram or per kg). If that value represents <0.025 mcg per gram, that would equal <25 ppm, which is above the gluten-free threshold; if it’s <0.025 mcg per kilogram, it would be extremely low and well within GF limits. Without the denominator, the result is incomplete. It’s reasonable to follow up with the company and ask them to confirm the result in ppm using a validated method (like ELISA R5)—that’s the standard used to assess gluten safety.
    • Scott Adams
      Medication sensitivity is very real for many people with celiac and other autoimmune conditions, and it’s frustrating when that’s brushed off. Even when a medication is technically gluten-free, fillers, dose changes, or how your nervous system reacts—especially with things like gabapentin—can cause paradoxical effects like feeling wired but exhausted. The fact that it helped bloating suggests it may be affecting gut–nerve signaling, which makes sense in the context of SIBO, but that doesn’t mean the side effects should be ignored. You’re carrying a heavy load right now with ongoing skin, eye, and neurological uncertainty, and living in that kind of limbo is exhausting on its own. It’s understandable to feel overwhelmed and discouraged when systems and providers don’t meet you where you are—your experience is valid, and continuing to advocate for yourself, even when it’s hard, really does matter. You can search this site for prescriptions medications, but will need to know the manufacturer/maker if there is more than one, especially if you use a generic version of the medication: To see the ingredients you will need to click on the correct version of the medication and maker in the results, then scroll down to "Ingredients and Appearance" and click it, and then look at "Inactive Ingredients," as any gluten ingredients would likely appear there, rather than in the Active Ingredients area. https://dailymed.nlm.nih.gov/dailymed/   
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.