Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Targeted Amino Acid Therapy


rock on

Recommended Posts

rock on Apprentice

Hi all!

It's been a long time since I've posted. For those of you who don't know me, I'm often here inquiring about things for my husband.

Anywho, he's been on a strict gluten free diet for over a year now for several reasons, but the main one being psoriatic arthritis.

He has gone off of his methotrexate (about 4 mos ago) and has been feeling relatively ok, except for some aches & pains here & there. His psoriasis is very mild & not having to take the pills has greatly improved his quality of life.

But, a new problem has arisen pretty severely over the last few months regarding anxiety, some depression & bad anxiety attacks.

An internist prescribed him ativan which has helped quite a bit, but we know isn't an answer to his problems.

A psychiatrist rx'd an antidepressant & a stronger anti-anxiety pill which my hubby hasn't filled the prescription for because he's nervous that taking those could cause another ride down a slippery slope.

Just yesterday we saw a D.O. & for the first time ever felt like we found a doctor who would actually listen...who actually cared about all of the issues that we feel are pertinent to my husband's medical history & who gave some hope to us that he could help my hubby get himself onto a track of health rather than simply masking all his various symptoms with pharmaceuticals. He sat with us for over 2 hours & really got specific about things that other doctors just wrote off. We are hopeful.

The first thing that he wants to do with my husband is start him on a Targeted Amino Acid Therapy to help to stabilize his neurotransmitters.

I've done some research & it seems to make sense (especially concerning my hubby's medical history)....but, I figured I would post here to see if any of you fine folks have had personal experiences with it or have known anyone who has tried the therapy.

As always, I thank you in advance for any info you all may be able to provide for us in our trek toward health for hubby (& our relationship!!)

Best~

RO


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Cinnamon Apprentice

I have a son with ADHD and dyspraxia, both of which are problems with dopamine in certain areas of the brain. I tried giving him tyrosine to boost his dopamine, and it worked amazingly well for a few days, then stopped working.

I tried giving him a higher dose, and that worked for another day or two, then stopped working. I was afraid to increase the dose any more, so I took him to the doctor, and this is what he told me. He said the brain is an amazing thing, it constantly monitors what comes in and makes adjustments accordingly. If you keep on giving it a high dose of only certain amino acids, it will make adjustments in order to dump it. But he said it depends on the plasticity of the person's brain. He said he's seen it work in a few adults, but not many. And he said it will never work in a child because their brains are so very plastic, constantly adjusting and changing.

It's worth a try, though. You never know, it might work and continue to work depending on the plasticity of his brain, which is less in adults. It sure did work for my son for those few days. Nothing including ADHD medication or gluten-free diet did as much to alleviate these problems.

I hope it works for you!

rock on Apprentice

Thanks Cinnamon. That's interesting that tyrosine helped him (even if it was for short periods).

I am certainly hopeful that this helps my guy. He's on the 2nd day of treatment...and treatment includes several types of amino acids in varying doses throughout the day.

We'll see. He says that he can feel that something is happening. He had some GI upset from it yesterday & the doctor lowered the dosage. He seems to be doing a little better today.

Perhaps something more comprehensive in an amino acid approach could help your son. So many things in our bodies rely on synergy...so many vitamins and minerals need to be balanced, so it figures that you should have to balance amino acids too.

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - GlorietaKaro replied to GlorietaKaro's topic in Super Sensitive People
      3

      Am I nuts?

    2. - trents replied to GlorietaKaro's topic in Super Sensitive People
      3

      Am I nuts?

    3. - lalan45 replied to xxnonamexx's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      29

      My journey is it gluten or fiber?

    4. - Russ H posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      0

      Anti-endomysial Antibody (EMA) Testing

    5. - Scott Adams replied to JoJo0611's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      1

      Just diagnosed today

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      132,806
    • Most Online (within 30 mins)
      7,748

    IleneG
    Newest Member
    IleneG
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Upcoming Events

  • Posts

    • GlorietaKaro
      Thanks to both of you for your responses!  Sadly, even after several years of very strict gluten avoidance, I remember the symptoms well enough that I am too frightened to risk a gluten challenge— heartbeat and breathing problems are scary— Scott, thank you for the specific information— I will call around in the new year to see if I can find anyone. In the meantime, I will carry on has I have been— it’s working! Thanks also for the validation— sometimes I just feel crushed by disbelief. Not enough to make me eat gluten though—
    • trents
      Welcome to the celiac.com community, @GlorietaKaro! As Scott indicated, without formal testing for celiac disease, which would require you to have been consuming generous amounts of gluten daily for weeks, it would be not be possible to distinguish whether you have celiac disease or NCGS (Non Celiac Gluten Sensitivity). Their symptoms overlap. The difference being that celiac disease is an autoimmune disorder that damages the lining of the small bowel. We actually no more about celiac disease than we do about NCGS, the mechanism of the latter being more difficult to classify. There are specific antibody tests for celiac disease diagnosis and there is also the endoscopy/biopsy of the small bowel lining. Currently, there are no tests to diagnose NCGS. Celiac disease must first ruled out. Researchers are working on developing testing methods to diagnose celiac disease that do not require a "gluten challenge" which is just out of the question for so many because it poses serious, even life-threatening, health risks. But we aren't there yet.
    • lalan45
      That’s really frustrating, I’m sorry you went through that. High fiber can definitely cause sudden stomach issues, especially if your body isn’t used to it yet, but accidental gluten exposure can feel similar. Keeping a simple food/symptom journal and introducing new foods one at a time can really help you spot patterns. You’re already doing the right things with cleaning and separating baking—also watch shared toasters, cutting boards, and labels like “may contain.”
    • Russ H
      I thought this might be of interest regarding anti-EMA testing. Some labs use donated umbilical cord instead of monkey oesophagus. Some labs just provide a +ve/-ve test result but others provide a grade by testing progressively diluted blood sample. https://www.aesku.com/index.php/ifu-download/1367-ema-instruction-manual-en-1/file Fluorescence-labelled anti-tTG2 autoantibodies bind to endomysium (the thin layer around muscle fibres) forming a characteristic honeycomb pattern under the microscope - this is highly specific to coeliac disease. The binding site is extracellular tTG2 bound to fibronectin and collagen. Human or monkey derived endomysium is necessary because tTG2 from other mammals does not provide the right binding epitope. https://www.mdpi.com/1422-0067/26/3/1012
    • Scott Adams
      First, please know that receiving two diagnoses at once, especially one you've never heard of, is undoubtedly overwhelming. You are not alone in this. Your understanding is correct: both celiac disease and Mesenteric Panniculitis (MP) are considered to have autoimmune components. While having both is not extremely common, they can co-occur, as chronic inflammation from one autoimmune condition can sometimes be linked to or trigger other inflammatory responses in the body. MP, which involves inflammation of the fat tissue in the mesentery (the membrane that holds your intestines in place), is often discovered incidentally on scans, exactly as in your case. The fact that your medical team is already planning follow-up with a DEXA scan (to check bone density, common after a celiac diagnosis) and a repeat CT is a very proactive and prudent approach to monitoring your health. Many find that adhering strictly to the gluten-free diet for celiac disease helps manage overall inflammation, which may positively impact MP over time. It's completely normal to feel uncertain right now. Your next steps are to take this one day at a time, focus on the gluten-free diet as your primary treatment for celiac, and use your upcoming appointments to ask all your questions about MP and what the monitoring plan entails. This dual diagnosis is a lot to process, but it is also the starting point for a managed path forward to better health. This article has some detailed information on how to be 100% gluten-free, so it may be helpful (be sure to also read the comments section.):    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.