Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

What Tests Should I Have Done For Celiac?

SLB5757

Recommended Posts

SLB5757 Enthusiast
SLB5757
Posted

Hello again!

First I want to say thank you for all the responses, and support on my previous post. I had one more question that I would liek to see if anyone can help with. I live in a small town and I do not think the physicians here are very "up to speed" on Celiac disease or the testing required for it.

I had a celiac test that came back negative a year ago. My doc had sent out bloodwork to an outside facility. I have asked that it be faxed to me so I can be more specific as to exactly what test it was. I also had an endoscopy two years ago - and I do not believe they did a biopsy for celiac at that time since they believed I had GERD. I have called the gastro that I went to to check and see if one was done at that time.

So my question is:

What specific tests should be done to rule out celiac? I have seen "Enterolab" on this board, and "IG something", and the biopsy via scope as being the "gold standard" for detection.

Thanks!!!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Lisa Mentor
Lisa
Posted
So my question is:

What specific tests should be done to rule out celiac? I have seen "Enterolab" on this board, and "IG something", and the biopsy via scope as being the "gold standard" for detection.

Thanks!!!

This is the panel that you should begin with:

Anti-gliadin antibodies (AGA) both IgA and IgG

Anti-endomysial antibodies (EMA) - IgA

Anti-tissue transglutaminase antibodies (tTG) - IgA

Total IgA level.

(you should remain on a full gluten diet for many weeks to aid in it's accuracy)

Unfortunately, testing is not as accuracy as we would like at this time. The Serologic Blood panel can rule Celiac in, but it cannot rule it out, as with the endoscopy/biopsy.

SLB5757 Enthusiast
SLB5757
Posted
  • Author
This is the panel that you should begin with:

Anti-gliadin antibodies (AGA) both IgA and IgG

Anti-endomysial antibodies (EMA) - IgA

Anti-tissue transglutaminase antibodies (tTG) - IgA

Total IgA level.

(you should remain on a full gluten diet for many weeks to aid in it's accuracy)

Unfortunately, testing is not as accuracy as we would like at this time. The Serologic Blood panel can rule Celiac in, but it cannot rule it out, as with the endoscopy/biopsy.

I just received the test back from my doctors that was done April of last year. They sent blood to the Mayo Clinic lab. The test that was ordered says Endomysial Abs, S (IgA). It says "negative" and that is the only words listed on the report. No levels as in numbers...just the words "negative".

The report states:

Test requested: Endomysial Abs, S (IgA)

Hi/Lo: Negative

Ref Range: Negative

Perform Site: MCR

My doc who is a CNP - just mailed it to me and said " your test for Celiac disease was negative". I may look into the other tests you have mentioned above. Thank-you.

Lisa Mentor
Lisa
Posted
I just received the test back from my doctors that was done April of last year. They sent blood to the Mayo Clinic lab. The test that was ordered says Endomysial Abs, S (IgA). It says "negative" and that is the only words listed on the report. No levels as in numbers...just the words "negative".

The report states:

Test requested: Endomysial Abs, S (IgA)

Hi/Lo: Negative

Ref Range: Negative

Perform Site: MCR

My doc who is a CNP - just mailed it to me and said " your test for Celiac disease was negative". I may look into the other tests you have mentioned above. Thank-you.

Here is additional information you might find important:

Open Original Shared Link

AWonderTree Rookie
AWonderTree
Posted

I don't mean to hijack this thread, but I basically have the same question as the topic's starter.

I'm feeling stupid because I'm having trouble understanding which tests weren't done on my report:

Reticulin Abs, S: Negative

Endomysial Abs, S: Negative

Gliadin(Deamidated) Ab, IgA, S: 2.9; <20.0 (Negative)

Gliadin(Deamidated) Ab, IgG, S: <1.0; <20.0 (Negative)

My questions:

  • What do these words and abbreviations mean: Abs, S, deamidated, Ab?
  • Are the first two any of the following (that I've read should be done)?
    Anti-gliadin antibodies (AGA) both IgA and IgG
    Anti-endomysial antibodies (EMA) - IgA
    Anti-tissue transglutaminase antibodies (tTG) - IgA
    Total IgA level.
  • Am I right to think that the last two on my report are "Anti-gliadin antibodies (AGA) both IgA and IgG"?
  • And the rest seem to be completely skipped. Hmmm.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      127,368
    • Most Online (within 30 mins)
      7,748
    Delsey
    Newest Member
    Delsey
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      70.1k
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Scott Adams
      Enegy level extremely low

      By Scott Adams · Posted

      Are there any things that you enjoy eating that you can have gluten-free versions of? For example, pizza, mac & cheese, pasta, etc? If so, perhaps try to include those in your diet more until your appetite recovers. Of course cannabis is famous for improving appetites, but I would only go that direction if you have serious weight + appetite issues that you can't solve via other methods.
    • Scott Adams
      Test result insight

      By Scott Adams · Posted

      Thanks for the follow up, and at least you know the cause of your health issues and can now start working towards better health! This article has some detailed information on how to be 100% gluten-free, so it may be helpful (be sure to also read the comments section.):    
    • trents
      Test Results

      By trents · Posted

      Oh, yes. When you reply with the reference ranges, please also add the units used such as mg/L or whatever. Different labs will used different units of measure just as they will deploy different reference ranges.
    • trents
      Test Results

      By trents · Posted

      Welcome to the forum, @breadbreadbaby! We cannot comment on your test numbers until you also provide the reference ranges used by the lab doing the analysis. Different labs construct the test analysis differently and used different reference ranges, Hence, there are no industry standards. You will likely have to repost the existing information in a new post as I don't think you will be able to edit your original. These two tests are the only ones that are celiac specific for which we need the reference ranges:  IgA - .98 Tissue transglutaminase IgA Ab 45.4  Urate and ferritin are not specific tests for celiac disease. Urate is a test for uric acid levels and would be something run when gout is suspected. Ferritin is an iron storage protein. Though not a celiac specific test, iron stores are often depleted in those with long term celiac disease because of the damage done to the lining of the small bowel by celiac disease. The small bowel is the portion of the intestinal track where all of the nutrition from what we eat is absorbed, including minerals like iron and the vitamins necessary to assimilate iron like B12. Many celiacs have few if any GI symptoms. This is common. We call them "silent celiacs". I was one of them. Silent celiacs are usually discovered indirectly because they develop health issues or irregular lab values indicative of vitamin and mineral malabsorption. In my case, it was elevated liver enzymes which had no other explanation. It took 13 years for me to get that figured out after the first appearance of elevated liver enzymes. By that time, I had experience significant bone demineralization.
    • breadbreadbaby
      Test Results

      By breadbreadbaby · Posted

      Just as a follow-up — I guess I’m wondering if I could have a false positive, despite how elevated it seems to be? My doctor said a biopsy doesn’t make sense considering the high result and the lack of GI symptoms but still unsure what I’ll do. 
×
×
  • Create New...