Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Celiac Panel Results - Help?

gatewaytobeing

Recommended Posts

gatewaytobeing Rookie
gatewaytobeing
Posted

Hi everyone,

A few weeks ago I asked my GYN to order the celiac bloodwork that someone here recommended. I just received a fax of the results, which are hard to read but here's what I have:

IGG - 99.00 (normal 649-1634) (does this mean I have an immune system disorder?)

IGA - 187.0 (normal 73-358)

IGM - 165.0 (normal 53-251)

Hemolysis Index - No Hemolysis

Icteric Index - 1 (0-15)

Lipemia Index - 4 (0-50)

Endomy IGA - Negative

Endomy A Titer - ?? (can't read some of this, it's T?P, then says SCREEN TEST NEGATIVE, TITER NOT PERFORMED

Gliadin IGA - 3 (no reference range given)

Gliadin IGG - 1 (no reference range given)

Any thoughts on this? My GYN says she's not trained to interpret for celiac. I am actually most concerned about the very low IGG.

Thanks all!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


FMcGee Explorer
FMcGee
Posted

Hi! Can your GYN refer you to a gastroenterologist, or can you find an internist who can handle that? Good luck!

gatewaytobeing Rookie
gatewaytobeing
Posted
  • Author

Hi - I was surprised to get only one reply to this. Can someone who understands this bloodwork please tell me if it rules out celiac? Or let me know if the low IGG is something to be concerned about? Thanks ...

Hi everyone,

A few weeks ago I asked my GYN to order the celiac bloodwork that someone here recommended. I just received a fax of the results, which are hard to read but here's what I have:

IGG - 99.00 (normal 649-1634) (does this mean I have an immune system disorder?)

IGA - 187.0 (normal 73-358)

IGM - 165.0 (normal 53-251)

Hemolysis Index - No Hemolysis

Icteric Index - 1 (0-15)

Lipemia Index - 4 (0-50)

Endomy IGA - Negative

Endomy A Titer - ?? (can't read some of this, it's T?P, then says SCREEN TEST NEGATIVE, TITER NOT PERFORMED

Gliadin IGA - 3 (no reference range given)

Gliadin IGG - 1 (no reference range given)

Any thoughts on this? My GYN says she's not trained to interpret for celiac. I am actually most concerned about the very low IGG.

Thanks all!

WW340 Rookie
WW340
Posted

The tests you had done are not the typical celiac panel. It would be difficult to make a celiac determination based on these numbers alone. That along with the very low IGG make this difficult to interpret, as it is possible the low IGG could be affecting the results.

I think your low IGG definitely needs to be evaluated further. Your GYN needs to refer you to someone who is experienced with this.

IGG has to do with your immunity. Your number looks very low. It could be a lab error, that happens, but it certainly needs further evaluation.

WW340 Rookie
WW340
Posted

Double post error.

gatewaytobeing Rookie
gatewaytobeing
Posted
  • Author

Hi, thanks for replying.

I had to go back and find my original post on this site where someone told me what tests to ask for. The celiac panel? They were:

1.Anti-gliadin antibodies (AGA) both IgA and IgG

2.Anti-endomysial antibodies (EMA) - IgA

3.Anti-tissue transglutaminase antibodies (tTG) - IgA

4.Total IgA level.

These are the tests that were on the script for the lab. My faxed print-out copy was admittedly hard to read.

Now that I have this list (above) in front of me, I can see how the two compare.

1. AGA-IgA = 3 and AGA-IgG = 1

2. EMA-IgA = negative

3. ??

4. ??

Instead of having a tTG-IgA and a Total IgA, I have an "IGG" and an "IGA" and an "IGM" as well as some sort of Icteric and Lipemia Index. Whether or not these correspond with what was ordered for lines 3-4, I don't know. Maybe only certain labs do these?

However, the first 2 lines seem correct? And are negative for celiac I assume?

Thanks again,

K

The tests you had done are not the typical celiac panel. It would be difficult to make a celiac determination based on these numbers alone. That along with the very low IGG make this difficult to interpret, as it is possible the low IGG could be affecting the results.

I think your low IGG definitely needs to be evaluated further. Your GYN needs to refer you to someone who is experienced with this.

IGG has to do with your immunity. Your number looks very low. It could be a lab error, that happens, but it certainly needs further evaluation.

WW340 Rookie
WW340
Posted

yes, the first two appear to be part of the celiac panel. Those are indicating negative for celiac.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      128,076
    • Most Online (within 30 mins)
      7,748
    pauline gallie
    Newest Member
    pauline gallie
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      70.6k
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • trents
      Celiac or Addison's complications? Can someone share their experience?

      By trents · Posted

      @KRipple, thank you for the lab results from your husband's celiac disease blood antibody testing. The lab result you share would seem to be the tTG-IGA (Tissue Transglutaminase IGA) and the test result is in excess of 10x normal. This is significant as there is an increasing tendency for physicians to grant a celiac disease diagnosis on the basis of antibody testing alone when the scores on that particular test exceed 10x normal. This trend started in the UK during the COVID pandemic when there was tremendous pressure on the medical system over there and it has spread to the USA. The tTG-IGA is the centerpiece of celiac disease blood antibody testing. All this to say that some doctors would grant a celiac disease diagnosis on your husband's bloodwork alone and not feel a need to go forward with an endoscopy with biopsy. This is something you and your husband might wish to take up with his physicians. In view of his many health issues it might be wise to avoid any further damage to his small bowel lining by the continuing consumption of gluten and also to allow healing of such to progress. The lining of the small bowel is the place where essentially all of our nutrition is absorbed. This is why celiac disease when it is not addressed with a gluten free diet for many years typically results in additional health problems that are tied to nutritional deficiencies. The millions and millions of tiny finger-like projections that make up the nutrient absorbing surface of the small bowel lining are worn down by the constant inflammation from gluten consumption. In celiac disease, the immune system has been tricked into labeling gluten as an invader. As these finger-like projections are worn down, the efficiency of nutrient absorption becomes more and more compromised. We call this villous atrophy.   
    • KRipple
      Celiac or Addison's complications? Can someone share their experience?

      By KRipple · Posted

      Thank you so much! And sorry for not responding sooner. I've been scouring the hospital records and can find nothing other than the following results (no lab info provided): Component Transglutaminase IgA   Normal Range: 0 - 15.0 U/mL >250.0 U/mL High   We live in Olympia, WA and I will be calling University of Washington Hospital - Roosevelt in Seattle first thing tomorrow. They seem to be the most knowledgeable about complex endocrine issues like APS 2 (and perhaps the dynamics of how APS 2 and Celiacs can affect each other). His diarrhea has not abated even without eating gluten, but that could be a presentation of either Celiac's or Addison's. So complicated. We don't have a date for endoscopy yet. I will let my husband know about resuming gluten.    Again, thank you so much for sharing your knowledge with me!
    • Jmartes71
      Celiac pain relief

      By Jmartes71 · Posted

      Ginger is my best friend, it helps alot with tummy issues..
    • aattana
      Positive gliadin (deamidated) IgG, normal everything else?

      By aattana · Posted

      Hi Phosphone, did you ever figure out what elevated your DGP?  I am in the same boat. 
    • trents
      Celiac or Addison's complications? Can someone share their experience?

      By trents · Posted

      Scott makes a good point about the prednisone. It has a general suppressing effect on the immune system. Don't misunderstand me. In view of your husband's several autoimmune afflictions, it would seem to be an appropriate medication therapy but it will likely invalidate endoscopy/biopsy test results for celiac disease.
×
×
  • Create New...