Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Other Causes Of Damaged Villi?


Laura9

Recommended Posts

Laura9 Rookie

Does anyone know if any illnesses other than Celiac Diseaes can cause flattened villi?

I had been very ill for 15 years until I was diagnosed with Celiac Disease 2 years ago. Upon being diagnosed, I immediately went gluten free and felt much better for about a year. I was diagnosed via an endoscopy which showed flattened villi and inflammation in the small intestine. I had previously had 2 Celiac blood tests before the endoscopy, both of which came back negative. After that first year of being gluten free, I had another endoscopy. My villi had returned to normal and the inflammation was gone. However, for the last year I have experience severe bloating, constipation, body aches and gas. I am totally gluten free. Through my readings, I came across articles that say if you continue to eat the same foods, e.g. quinoa, you can develop an autoimmune response to that food. Has anyone experienced this? Thank you.

Laura


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



jststric Contributor

I am not a diagnosed Celiac. I believe myself ti be gluten-intolerant. I've been afraid of that very thing, as I am intolerant ofany things, leaving my choices few. If I ever start having problems with corn or soy, I will be in big trouble. But, so far, so good. I've been doing this for about 3 yrs.

mushroom Proficient

I developed an intolerance to citric acid 18 months after giving up gluten. Used a lot of lemons and juice, was eating lots of mandarins and bammo!! For me, it was itching. But potates and soy make me itch also. So yes, you do have to vary your diet. I am also an undiagnosed gluten intolerant (and soy, corn, nightshades).

T.H. Community Regular

I don't know if other diseases cause flattened villi, but I would assume so. I ended up getting the biopsy first, and they still insisted on doing a blood test to 'confirm' celiac.

That seems to me like it means there are other possible causes of flattened villi, yes?

However, my GI had some stuff to say about the food sort of thing.

This is what he told me, in a nutshell.

1. Celiacs are more likely to be sensitive to dyes, additives, and preservatives in their food.

2. Celiacs are more likely to have food allergies, intolerances, and sensitivities, and to develop food allergies to foods if they consume them on a daily basis.

3. Celiacs are more likely to react to genetically modified foods, usually by developing food allergies to OTHER foods (In studies, eating lots of genetically modified soy, for ex, seems to make animals develop peanut allergies. Weird stuff).

So he puts all his celiac patients on a rotation diet, with only organic (non-GM) foods, where you don't eat the same food for more than a day or two in a row.

Easiest way to check it is if you can change your diet so you are eating a food once every 2 or three days, and keep a log of your symptoms. See if something pops, yes? We did the elimination diet on top of this, where we took out all foods derived from the 8 major allergens. Found a few foods that did bad stuff to us, and now the family is feeling much better!

so sorry you are not, but I hope that you will find the answer soon.

Does anyone know if any illnesses other than Celiac Diseaes can cause flattened villi?

I had been very ill for 15 years until I was diagnosed with Celiac Disease 2 years ago. Upon being diagnosed, I immediately went gluten free and felt much better for about a year. I was diagnosed via an endoscopy which showed flattened villi and inflammation in the small intestine. I had previously had 2 Celiac blood tests before the endoscopy, both of which came back negative. After that first year of being gluten free, I had another endoscopy. My villi had returned to normal and the inflammation was gone. However, for the last year I have experience severe bloating, constipation, body aches and gas. I am totally gluten free. Through my readings, I came across articles that say if you continue to eat the same foods, e.g. quinoa, you can develop an autoimmune response to that food. Has anyone experienced this? Thank you.

Laura

  • 1 year later...
hosette Newbie

Kwashiorkor (severe protein deficiency) is the only other cause I can think of... you can look it up

lcarter Contributor

Yes, other diseases can cause villi blunting:

Open Original Shared Link

"Endoscopic findings of the descending duodenum associated with celiac disease may include absence of folds, scalloped folds, visible submucosal blood vessels, mucosal mosaic pattern, and absence of villi. At histology, chronic inflammation of the duodenal mucosa with blunting or absence of villi accompanied by crypt hyperplasia is characteristic.

Although villous atrophy is not exclusive of celiac disease, it is considered a crucial finding. Other causes of blunted villi include tropical sprue, malnutrition, intolerance to cow's milk, soy protein intolerance, and infectious gastroenteritis. However, most of these conditions can be readily excluded on the basis of clinical history and laboratory data."

sahm-i-am Apprentice

Yes, I have read that there are other things that can cause the intestinal villi to flatten. Cow milk being one that I can think of immediately. I read somewhere that corn is starting to do that to patients because food manufacturers are using so much of it in our foods, but I can't stand behind that until I find some more information. There are a few other diseases that cause villi blunting, too. If you Google it I'm sure some information will pop up.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      126,632
    • Most Online (within 30 mins)
      7,748

    Lynn Reed
    Newest Member
    Lynn Reed
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.9k
    • Total Posts
      69.5k

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • jjiillee
      I got her results in the app but waiting for call from her doctor. Not sure what it means but maybe not celiac since villi are normal??  FINAL DIAGNOSIS: Duodenal biopsy (#1): DUODENAL MUCOSA WITH NO SIGNIFICANT ABNORMALITY. NO SIGNIFICANT VILLUS BLUNTING NOR INCREASED INTRAEPITHELIAL LYMPHOCYTES. Duodenal bulb biopsy (#2): MILD ACUTE DUODENITIS WITH FOCAL FOVEOLAR METAPLASIA. NO SIGNIFICANT VILLUS BLUNTING NOR INCREASED INTRAEPITHELIAL LYMPHOCYTES Gastric antral biopsy (#3): MILD CHRONIC FOCALLY ACTIVE GASTRITIS. PENDING IMMUNOSTAIN FOR HELICOBACTER ORGANSIMS (TO BE REORTED IN AN ADDENDUM). Gastric body biopsy (#4): GASTRIC OXYNTIC MUCOSA WITH NO SIGNIFICANT ABNORMALITY. Esophageal biopsy, distal (#5): SQUAMOUS MUCOSA WITH NO SIGNIFICANT ABNORMALITY. Esophageal biopsy, mid (#6): SQUAMOUS MUCOSA WITH NO SIGNIFICANT ABNORMALITY
    • Russ H
      I doubt very much that it contains any gluten. It works by producing an artificial blood clot, mixing 2 or more proteins found in the natural blood clotting cascade. These are refined from human blood donations. It comes in 2 vials that are mixed immediately before use and clot quickly.
    • nanny marley
      This literally happened to me today I had gluten after not eating it for over 6 months doing the elimination diet has I'm trying to get help with a diagnosis I ate gluten a few days ago and then stopped  because I went for my blood test today unfortunately it's not enough has I've now learned from some helpful people on this forum it has to be a lot longer before a test but my food today was really salty I just thout it was me because I'd deviated off my diet but I definitely tasted my  food  salty so that's a very intriguing investigation for me now thankyou for the post 
    • nanny marley
    • Scott Adams
      Here is more info about how to do a gluten challenge for a celiac disease blood panel, or for an endoscopy: and this recent study recommends 4-6 slices of wheat bread per day:    
×
×
  • Create New...