Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Lab Results


Carin3

Recommended Posts

Carin3 Rookie

Hi! I was recently diagnosed with Celiac in Novemember 2009. I have barely any of the GI symptoms of celiac but almost all the non-GI symptoms of celiac!! I started seeing a hematologist for chronic iron deficency anemia which didn't improve with iron pills. She sent me to a GI doc who did a endo and colonoscopy. My biopsy came back saying small bowel mucosa showing minimal loss of the villous structures (mild blunted villi); increased density of intraepithelial lymphocytes and hyperplasia of the crypts. Marked increase in intraepithelial lymphocytes of superficial villous epithellum. So one GI doc didnt think it was celiac and sent the biopsy for a second opinion (he also told me not to go gluten-free if I could control my anmeia with iron pills!)to yale. There biopsy report reads: We concur with the original pathology interpretation. biopsies reveal normal to minimally abnormal villous architecture. There is a definite increase in intraepithelial lymphocytes. Then in the end of November I got a IV iron transfusion (my hgb was dropping). November 1st I started going gluten free. I do feel better but unlike a lot of you I don't have the GI symptoms so it is hard er for me to tell. A couple weeks ago I went back to the hematologist and my hgb is within the normal range for the first time in like 15 years!! After the IV iron in November she did not have me take any supplemental iron. Before I forget before going gluten-free the GI doctor did the TTG IgA and IgA both normal. I dont mind being gluten-free but want your opinions as to if you think I have celiac or not. I would love to hear what you have to say!! Thanks!! Now moving on to my son. He is 4 y.o and has had GI issues since he was 2 (well he did have reflux as a baby). He has had about 5 endoscopy's and one colonoscopy. His first endo at 2 they found a large nasty stomach ulcer in the fundu area of the stomach and they found chronic reflux esophagitis, about a year later they found a duodental ulcer (while on reflux/ulcer meds), duodenitis and reflux esophagitis, another newer endoscopy showed the duodenitis and esophagiits. During each endoscopy they have taken biopsies for celiac which have come back negative-although the doctor DID NOT know that I may have it. He freuqently complains of stomach pain,throat pain and we have a lot of problems with him pooping in his underwear (although that seems to come and go). We recently had to switch pediatric GI docs b/c our stopped taking insurance (and this may have been a blessing). We are now seeing a peds GI at CHildrens National Medical Center in DC (this new doc does know about me). He ordered a ton of lab work (including celiac panel and celiac genetic). All his lab work came back normal including the celiac panel (but remember mine was normal as well). I just got a call today that said he has the gene for celiac but is low risk. I am very confused by that and I hoping some of you might explain. If I do have celiac and he carries the gene wouldnt that put him at a higher risk for getting celiac? I realize the doctor is busy and we have only seen him once so far so he might have forgotten that I thinki I have celiac. He is getting a endoscopy and ph probe (never had that done to check out the reflux) on Tuesday b/c he continues to have some belly pain and its not good for him to continue to have the duodenitis. Any opinions would be helpful. I am sure tuesday I can find out more about what the genetic testing said but would love to hear what you all have to say. Every test any doctor has ever done on my son has been normal and they have never been able to firgure out why he had the two ulcers and the duodenitis. I am wondering if we could finally have an answer or not. SORRY this is so long but sooooo confused about myself and my son. I have found these forum VERY helpul in the past 4 months and appreciate everything. Thanks!!!


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



tarnalberry Community Regular

Your bloodwork isn't very useful. They (apparently) only tested for IgA antibodies, and not a total IgA count or IgG antibodies. IgA deficiency is fairly common in celiacs, so without a total IgA count, the IgA antibody tests are useless.

ravenwoodglass Mentor

I am going to put it short and sweet. I would give him a couple of months trial on the diet after all the testing is done. False negatives in children are even more common than in adults.

string bean Newbie

Your bloodwork isn't very useful. They (apparently) only tested for IgA antibodies, and not a total IgA count or IgG antibodies. IgA deficiency is fairly common in celiacs, so without a total IgA count, the IgA antibody tests are useless.

I had a celiac panel done and the only thing that came back high was my total IgA. So, I understand that to mean I am not IgA deficient, but what does an abnormally high total IgA mean?

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - RMJ replied to marion wheaton's topic in Related Issues & Disorders
      6

      Osteoporosis

    2. - trents replied to marion wheaton's topic in Related Issues & Disorders
      6

      Osteoporosis

    3. - RMJ replied to marion wheaton's topic in Related Issues & Disorders
      6

      Osteoporosis

    4. - trents replied to marion wheaton's topic in Related Issues & Disorders
      6

      Osteoporosis

    5. - marion wheaton replied to marion wheaton's topic in Related Issues & Disorders
      6

      Osteoporosis


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      126,438
    • Most Online (within 30 mins)
      7,748

    Wbymw
    Newest Member
    Wbymw
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.9k
    • Total Posts
      69.4k

  • Celiac.com Sponsor (A22):




  • Who's Online (See full list)


  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • RMJ
      Vitamin K is also thought to help bone health, although not all scientific studies agree. 
    • trents
      @marion wheaton, are you on vitamin and mineral supplements that are appropriate for bone health in order to offset the malabsorption problem until your gut heals thoroughly? I'm talking about supplements more potent than an adult multivitamin. We routinely recommend to newly diagnosed celiacs to be taking a high potency B-complex, 5-10k of D3, Magnesium glycinate or Magnesium citrate, and zinc picolinate. All supplements need to be gluten free of course.
    • RMJ
      I’ve been taking oral alendronate for 4 years.  I haven’t had any doctors be concerned about it.  My dentist recommended against the related iv medications because of potential adverse effects on the bones in the jaw - osteonecrosis.  Supposedly rare side effect but he had seen it several times. I originally had the same concern as @trents - slowing resorption instead of building new bone.  I learned that that was a problem with the original bisphosphonates but not so much with alendronate and other newer ones.
    • trents
      Both are valid concerns IMO. I developed osteopenia from celiac disease and was taking alendronate for a time. Honestly though, I can't remember if it was before diagnosis or after diagnosis of celiac disease. I was diagnosed over twenty years ago. I don't remember having any problems with the med itself but I do remember stopping it because I was concerned about the mechanism of its action. Namely, it slows down the resorption of old bone cells rather than speeding up the production of new ones. My concern was that it might increase bone mass but actually result in softer bones. That may have been a dated concern but back then it was a reservation held by some in the medical community. And then there are all the potential side effects and drug interactions associated with it. I think once the villous lining of my small bowel began to heal and nutrient absorption improved, the bone demineralization problem at least stabilized. I am now 73 and have had no problems with fractures but I did develop kyphosis (forward curvature of the upper spine) and a little scoliosis previous to the celiac diagnosis which, of course, are irreversible. I have some occasional problems with nerve impingement in the neck as a result of the original demineralization but all in all, not as many problems as I expected. At least to this point. I do some modest weight lifting pretty regularly so I think that has helped restrengthen my bones.  My experience may not be normative, however, and there is also the difference between male and female hormones and their effect on bone health. Found this: https://www.drugs.com/tips/alendronate-patient-tips
    • marion wheaton
      They are concerned about the GI side effects and malabsorption of the medication. 
×
×
  • Create New...