Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Gene Question......

Luvbeingamommy

Recommended Posts

Luvbeingamommy Contributor
Luvbeingamommy
Posted

My son and I both had our genes tested through enterolab, my doctor ended up checking mine too. If I have 2,6 and my son has 2,7, where did he get the "7" ? Does this mean my husband carries it??

would it be a good idea to get my other two children checked, one is almost 5 and one is 10 months. My 2 year old is the one who was having major GI issues. I just kind of want to know if one of my kids has the 6 like I do, because neuro issues can be pretty serious and I just got so blessed that my stroke hit the part of the brain it did.

If I asked our family doctor to check their genes, they wouldn't check the sensitivity part. Maybe I'd be best to go through Enterolab??

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Korwyn Explorer
Korwyn
Posted

Hi Luvbeingamommy!

Yes, the "DQ7" gene would have come from your husband. Enterolab seems to test the widest set of genes that I have been able to find, though someone else on here might have more info. I know Prometheous didn't test for anything more than the two main genes as of the last time I checked.

Luvbeingamommy Contributor
Luvbeingamommy
Posted
  • Author

Really, interesting. So if my kiddos will have a gluten sensitive gene it will be either 6 or 7??

You think it's a good idea to test or only if issues come up??

frieze Community Regular
frieze
Posted

Really, interesting. So if my kiddos will have a gluten sensitive gene it will be either 6 or 7??

You think it's a good idea to test or only if issues come up??

your husband has another gene for that loci (or whatever the proper term is,lol) it is likely that it would show up in your other children....

Luvbeingamommy Contributor
Luvbeingamommy
Posted
  • Author

your husband has another gene for that loci (or whatever the proper term is,lol) it is likely that it would show up in your other children....

Hmm, all this gene stuff is confusing! Maybe someday I will understand....

Korwyn Explorer
Korwyn
Posted

Ok I'll try and give you a quick synopsis. :)

There are 8 (possibly 9) genes identified as being related to celiac disease and/or gluten intolerance. A person could potentially have up to two genes - one from each of parent. This is very very over simplified, but basic. The percentages have much to do with dominant and recessive genes and things, but basically that it what it boils down to.

There are others on this board that can give you a much more accurate and detailed explanation about them and what the different genes seem to trigger (so far as research has uncovered to date). DQ7 is one of the more complex of the genes in terms of how it is (or isn't) linked to various other auto-immune diseases as it appears to act differently depending on your genetic ethnic genotype and what other genes are nearby.

Luvbeingamommy Contributor
Luvbeingamommy
Posted
  • Author

Interesting, I had not read much about the 7, a little on the 6 though.

Okay it makes sense to me now, at least much more :). I am not sure whether or not to get my other two kiddos tested, or even my husband??

Fussy baby, but thanks for your response!!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


ravenwoodglass Mentor
ravenwoodglass
Posted

Interesting, I had not read much about the 7, a little on the 6 though.

Okay it makes sense to me now, at least much more :). I am not sure whether or not to get my other two kiddos tested, or even my husband??

Fussy baby, but thanks for your response!!

I would encourage your husband to be tested. Your children definately should be tested now and test them again at puberty, that is what they do in countries that screen everyone. Then retest them if they start to show symptoms. Do keep in mind that the testing on children has an even higher rate of false negatives than with adults so if they seem symptomatic a trial of the diet is in order.

I would not do this with gene testing as not everyone who carries the genes develops celiac. The gene testing can be interesting but is not diagnostic.

  • 2 weeks later...
Luvbeingamommy Contributor
Luvbeingamommy
Posted
  • Author

I would encourage your husband to be tested. Your children definately should be tested now and test them again at puberty, that is what they do in countries that screen everyone. Then retest them if they start to show symptoms. Do keep in mind that the testing on children has an even higher rate of false negatives than with adults so if they seem symptomatic a trial of the diet is in order.

I would not do this with gene testing as not everyone who carries the genes develops celiac. The gene testing can be interesting but is not diagnostic.

So would you say test my children that aren't showing many symptoms?? My almost 5 year old has always had, "poop issues". He use to struggle with constipation, but now it's weird I have to force him to poop or he won't. He fights it, but then usually does go.

My daughter is only 11 months old, I am just going pretty light on the gluten with her, mainly because with my son and myself being gluten free she is mainly too.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,879
    • Most Online (within 30 mins)
      7,748
    Peta Dunn
    Newest Member
    Peta Dunn
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • cristiana
      Ibuprofen

      By cristiana · Posted

      Ferritin levels.  And see what your hemoglobin looks like too, that will tell you if you are anemic?  You can have 'low normal' levels that will not be flagged by blood tests.  I had 'low normal' levels, my lab reading was. c12, just over what was considered normal, but I had small benign lesion on my tongue, and sometimes a sore mouth, and a consultant maxillofacial ordered an iron infusion for me as he felt my levels were too low and if he  raised them to 40, it would help.   Because you are not feeling 100% it might be worth looking at your levels, then discussing with your doctor if they are low normal.  But I stress, don't supplement iron without your levels being monitored, too much is dangerous.
    • Mari
      New here

      By Mari · Posted

      Hi Katht -  I sympathize with your struggles in following a gluten-free diet and lifestyle. I found out that I had Celiac Disease a few months before I turned 70. I just turned 89 and it has taken me almost 20 years to attain a fairly normal intestinal  function. I also lost a lot of weight, down to 100 lb. down from about 140 lb. What Trents wrote you was very true for me. I am still elimination foods from my diet. One person suggested you keep a food diary and that is a good idea but it is probably best just to do an elimination diet. There are several ne and maybe one for celiacs. I used one for a while and started with plain rice and zucchini and then added back other foods to see if I reacted or not. That helped a great deal but what I did not realise that it would only very small amounts of some foods to cause inflammation in my intestine. Within the last few years I have stopped eating any trace amounts of hot peppers, corn and soy(mostly in supplements) and nuts, (the corn in Tylenol was giving me stomach aches and the nuts were causing foot pains). Starting an elimination diet with white rice is better than brown rice that has some natural toxins. In addition it is very important to drink sufficient plain water. You can find out how much to drink for your height and weight online. I do have difficulty drinking 48 ounces of water but just recently have found an electrolyte supplement that helps me stay well hydrated, Adding the water and electrolytes may reduce muscle cramps and gag spams you wrote about. . Also buy some anti-gluten enzyme capsules to take with meals. I use GliadinX advertised here. These are a lot of things to do at one time as they reflect my 20 years of experience. I hope you do what you can manage to do over time. Good luck and take care.
    • Colleen H
      Ibuprofen

      By Colleen H · Posted

      Yes thyroid was tested.. negative  Iron ...I'm. Not sure ... Would that fall under red blood count?  If so I was ok  Thank you for the detailed response..☺️
    • Colleen H
      Methylprednisone treatment for inflammation?

      By Colleen H · Posted

      Hi all !! Did anyone ever get prescribed methylprednisone steroids for inflammation of stomach and intestines?  Did it work ??  Thank you !! 
    • cristiana
      Ibuprofen

      By cristiana · Posted

      Hi Colleen Are you supplementing B12/having injections? I have learned recently that sometimes when you start addressing a B12 deficiency, it can temporarily make your symptoms worse.  But it is important not to stop the treatment.  Regarding your problems with anxiety, again that is another symptom of a B12 deficiency.   I didn't know what anxiety was until it hit me like a train several months before gastrointestinal issues began, so I can certainly relate.   Two books which helped me hugely were At Last A Life by Paul David (there is a website you can look up) and The Depression Cure: The Six-Step Programme to Beat Depression Without Drugs by Dr Steve Llardi.  Although his book is aimed at people who have depression, following the principals he sets out was so helpful in lessening my anxiety.  Llardi suggests we need to focus on getting enough: - physical exercise - omega-3 fatty acids - natural sunlight exposure - restorative sleep - social connectedness - meaningful, engaging activity   ... and we should feel a lot better. That is not to stay you must stop taking medication for depression or anxiety if you have been prescribed it, but adopting the changes Dr Llardi sets out in the book should really help. Can I just ask two more questions:  1) you say that you are B12 deficient, did they test your iron levels too?  If not, you really ought to be checked for deficiency and, 2) did they check your thyroid function, as an overactive thyroid can be cause rapid heartbeat and a lot of coeliacs have thyroid issues? Cristiana        
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.