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Celiac And Infertility


ivfmama31

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ivfmama31 Newbie

I was recently diagnosed with Celiac. Now I'm starting to connect the dots wondering if that was the mystery behind my daughter's IUGR and preterm birth, and my first two second trimester losses, all of which are unexplained.

My husband and I would love to have another baby, and are secretly hoping that going gluten free may be at least a little bit of a help. My husband hasn't been officially diagnosed, but I really think he at least has a sensitivity to gluten(we'll find out shortly). We both had fertility issues, his unexplained, mine PCOS and went through 6 rounds of IVF before finally having a live birth.

Does anyone know how having celiac may effect fertility in males? I'm hoping if going gluten free boosts my chances it may boost his too. Not only that but I'm hoping it makes a subsequent pregnancy go a little smoother, and maybe make it closer to that full term mark.


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Grace'smom Explorer

Hi there,

I'm a parent of a celiac child, and I haven't experienced pregnancy w/celiac myself, but I did want to say that I've read a lot of posts from other women who experienced sometimes multiple miscarriages and infertility when their celiac disease was undiagnosed and untreated. They then went on to have healthy babies after going gluten free. I saw several threads on the topic a few down from yours titled something like, "pregnancy with diagnosis, so different from before diagnosis". I thought you might want to read it as there were several stories like your own. I'll say a prayer for you that you deliver a healthy happy baby. Take care, Emily

i-geek Rookie

I've heard that celiac can affect both male and female fertility- usually in both cases due to nutrient malabsorption. My husband and I started trying to have children a little over 6 years ago. I had one early miscarriage that coincided with a bad flare-up of otherwise latent (or so I thought) celiac disease 5 years ago. I went gluten-free right after Christmas 2009. Now the husband is starting to suspect that he has problems with gluten based on reactions to gluten foods after a mostly gluten-free diet (his uncle is a confirmed celiac, another uncle has been told to eat a gluten-free diet, and his mother has a whole host of mysterious health issues). I wonder if we'd be able to have children if he also went gluten-free...

Lisa Mentor

Celiac has many symptoms and can create lots of collateral damage:

Open Original Shared Link

REPRODUCTIVE SYSTEM SYMPTOMS IN MALES IN CELIAC DISEASE

Disorders of organ structure and function.

* Hypogonadism

* Impotence

* Infertility

* Sperm Abnormalities

Archived

This topic is now archived and is closed to further replies.


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    • trents
      @KRipple, thank you for the lab results from your husband's celiac disease blood antibody testing. The lab result you share would seem to be the tTG-IGA (Tissue Transglutaminase IGA) and the test result is in excess of 10x normal. This is significant as there is an increasing tendency for physicians to grant a celiac disease diagnosis on the basis of antibody testing alone when the scores on that particular test exceed 10x normal. This trend started in the UK during the COVID pandemic when there was tremendous pressure on the medical system over there and it has spread to the USA. The tTG-IGA is the centerpiece of celiac disease blood antibody testing. All this to say that some doctors would grant a celiac disease diagnosis on your husband's bloodwork alone and not feel a need to go forward with an endoscopy with biopsy. This is something you and your husband might wish to take up with his physicians. In view of his many health issues it might be wise to avoid any further damage to his small bowel lining by the continuing consumption of gluten and also to allow healing of such to progress. The lining of the small bowel is the place where essentially all of our nutrition is absorbed. This is why celiac disease when it is not addressed with a gluten free diet for many years typically results in additional health problems that are tied to nutritional deficiencies. The millions and millions of tiny finger-like projections that make up the nutrient absorbing surface of the small bowel lining are worn down by the constant inflammation from gluten consumption. In celiac disease, the immune system has been tricked into labeling gluten as an invader. As these finger-like projections are worn down, the efficiency of nutrient absorption becomes more and more compromised. We call this villous atrophy.   
    • KRipple
      Thank you so much! And sorry for not responding sooner. I've been scouring the hospital records and can find nothing other than the following results (no lab info provided): Component Transglutaminase IgA   Normal Range: 0 - 15.0 U/mL >250.0 U/mL High   We live in Olympia, WA and I will be calling University of Washington Hospital - Roosevelt in Seattle first thing tomorrow. They seem to be the most knowledgeable about complex endocrine issues like APS 2 (and perhaps the dynamics of how APS 2 and Celiacs can affect each other). His diarrhea has not abated even without eating gluten, but that could be a presentation of either Celiac's or Addison's. So complicated. We don't have a date for endoscopy yet. I will let my husband know about resuming gluten.    Again, thank you so much for sharing your knowledge with me!
    • Jmartes71
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    • aattana
      Hi Phosphone, did you ever figure out what elevated your DGP?  I am in the same boat. 
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      Scott makes a good point about the prednisone. It has a general suppressing effect on the immune system. Don't misunderstand me. In view of your husband's several autoimmune afflictions, it would seem to be an appropriate medication therapy but it will likely invalidate endoscopy/biopsy test results for celiac disease.
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