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Trans-glutaminase Antibodies Test


lucky28

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lucky28 Explorer

Does anyone have an opinion or have experience with this test. I ordered one from "great plains lab" and was not sure if this was the best type of test to use to confirm or not. I have no insurance and I am a full time student on a tight budget but I really want to find out if I do have celiac or not. I think I do but then again maybe it is something else. I am looking for the least expensive yet most reliable test I can find. If anyone has advise --Thank You

ps> I was gluten-free for about a month and had my first normal bm in about 20yrs. but I began a gluten challenge 2 days ago and no D -- yet ;) but massive bloating :o, could be gluten or the cheese on my sandwich at work today- I know for sure I'm lactose int. but a slice of cheese is usually ok


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KaitiUSA Enthusiast

If you were gluten free for a month then that can interfere with the accuracy of tests. The tTG test is one of the most specific tests for celiac so yes that is a good test to get done. I had this test done by prometheus labs and it came back high.

KarenCM Rookie

It is also a good idea to have the IgA test along with the TTG test in case you are IgA deficient with celiac disease. If you are IgA deficient and have celiac disease the test can sometimes come back as a false negative.

Karen

lucky28 Explorer

Thanks karen and kaiti for the replies. I think I'm not going to be able to stay on the gluten challenge until the 23rd (my appt). I just don't want to go through the bloating, big D, crampy, tired and foggy way I feel :blink: . I spent the last 10++ years feeling like cr**. and it seems worse now since I had been gluten-free for over a month. Plus I don't have insurance and I start school in 3 weeks, full time in addition to a full time job. I think I would rather spend the $$ on gluten-free foods than on the tests that will tell me I need to buy gluten-free.

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    • trents
      Take it easy! I was just prompting you for some clarification.  In the distillation process, the liquid is boiled and the vapor descends up a tube and condenses into another container as it cools. What people are saying is that the gluten molecules are too large and heavy to travel up with the vapor and so get left behind in the original liquid solution. Therefore, the condensate should be free of gluten, no matter if there was gluten in the original solution. The explanation contained in the second sentence I quoted from your post would not seem to square with the physics of the distillation process. Unless, that is, I misunderstood what you were trying to explain.
    • Mynx
      No they do not contradict each other. Just like frying oil can be cross contaminated even though the oil doesn't contain the luten protein. The same is the same for a distilled vinegar or spirit which originally came from a gluten source. Just because you don't understand, doesn't mean you can tell me that my sentences contradict each other. Do you have a PhD in biochemistry or friends that do and access to a lab?  If not, saying you don't understand is one thing anything else can be dangerous to others. 
    • Mynx
      The reason that it triggers your dermatitis herpetiformis but not your celiac disease is because you aren't completely intolerant to gluten. The celiac and dermatitis herpetiformis genes are both on the same chronometer. Dermatitis herpetoformus reacts to gluten even if there's a small amount of cross contamination while celiac gene may be able to tolerate a some gluten or cross contamination. It just depends on the sensitivity of the gene. 
    • trents
      @Mynx, you say, "The reason this is believed is because the gluten protein molecule is too big to pass through the distillation process. Unfortunately, the liquid ie vinegar is cross contaminated because the gluten protein had been in the liquid prior to distillation process." I guess I misunderstand what you are trying to say but the statements in those two sentences seem to contradict one another.
    • Mynx
      It isn't a conjecture. I have gotten glitened from having some distilled white vinegar as a test. When I talked to some of my scientists friends, they confirmed that for a mall percentage of people, distilled white vinegar is a problem. The cross contamination isn't from wheat glue in a cask. While yhe gluten protein is too large to pass through the distillation process, after the distillation process, the vinegar is still cross contaminated. Please don't dismiss or disregard the small group of people who are 100^ gluten intolerant by saying things are conjecture. Just because you haven't done thr research or aren't as sensitive to gluten doesn't mean that everyone is like you. 
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