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Tissue Transglutaminase (ttg)

Emme999

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Emme999 Enthusiast
Emme999
Posted

Well, my dad was finally tested for celiac disease - which I *really* thought he had, because of his many problems that seem to correlate. But - his tTG score was only 3. So.. this led me to wonder what mine was!

My score was 23.4 - does anyone know about the "normal" range? My dad's doctor said normal range was anything below 19, but then my doctor told me that normal range was anything below 7. All I know for sure is that mine seems high.

If you know your score, please share :) I'm interested!

And what does it mean if your score is "really" high versus "kinda" high anyway?

Please let me know if you know :)

Thanks!

- Michelle :wub:

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KaitiUSA Enthusiast
KaitiUSA
Posted

Different labs vary with the ranges of normal.

My lab said anything below a 4 was normal...I had a 10

nikki-uk Enthusiast
nikki-uk
Posted

My husband's ttg was 12 which was classed at borderline(biopsy positve though)

My son's recent results are7 which again are classed as borderline-but docs are now checking his ferratin levels looking for more signs.

The number scored therefore can vary enormously.Would your Dad consider doing a trial gluten-free period to see if he has a positive response?

Carriefaith Enthusiast
Carriefaith
Posted

Mine was high, like 20 or 30 something, I don't really remember the exact number though. I believe the normal in my lab was 7.

SueC Explorer
SueC
Posted

MIne was 187!! The normal range for my lab is 0-19.

Does anyone else have a level that high?

Sue.

bklyn Enthusiast
bklyn
Posted

Yup, mine was 194.

SueC Explorer
SueC
Posted

Hi Kathy,

Did your levels go down? If so how long did it take?

Sue

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lovegrov Collaborator
lovegrov
Posted

Mine was 177 with anything above 19 positive. It was normal 14 months later but probably was actually down before that.

richard

bklyn Enthusiast
bklyn
Posted

I was at 5 after about six months.

skbird Contributor
skbird
Posted

Michelle - was that the only test your dad had, or did he have others?

Stephanie

Sharon C. Explorer
Sharon C.
Posted

Hi-

My son is going back for a follow up after being diagnosed last October with Celiac. They are testing him with this same test. They are not doing a Gliadin/IgG-IgA. Just a tTG, and also thyroid function and also CBC/platlet. Is this a normal way to check to see if levels have gone down?

Also, when my son was diagnosed, I asked my doctor to screen me. He had NEVER screened anyone for gluten intolerance before. He sent me for the Gliadin IgG-IgA test but NOT the tTG. He said it "seemed" like I was negative. Is this the proper way to screen someone?

nikki-uk Enthusiast
nikki-uk
Posted

Hi Sharon-the ttg is specific to coeliac disease,and you should have had it with the other tests.Without the ttg,your levels of iGg/igA would not really mean much(other than high levels would mean all is not well in your body).

However for your son,just testing his tTg levels is a normal way in diagnosed coeliac to see if his antibodies to gluten are going down now he's gluten-free.

Hope that helps.

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    • trents
      Hidden Gluten in distilled vinegar

      By trents · Posted

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      No they do not contradict each other. Just like frying oil can be cross contaminated even though the oil doesn't contain the luten protein. The same is the same for a distilled vinegar or spirit which originally came from a gluten source. Just because you don't understand, doesn't mean you can tell me that my sentences contradict each other. Do you have a PhD in biochemistry or friends that do and access to a lab?  If not, saying you don't understand is one thing anything else can be dangerous to others. 
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      The reason that it triggers your dermatitis herpetiformis but not your celiac disease is because you aren't completely intolerant to gluten. The celiac and dermatitis herpetiformis genes are both on the same chronometer. Dermatitis herpetoformus reacts to gluten even if there's a small amount of cross contamination while celiac gene may be able to tolerate a some gluten or cross contamination. It just depends on the sensitivity of the gene. 
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