Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Confused About Casein


rogue

Recommended Posts

rogue Rookie

After being gluten free for nearly 6 years, it turns out that I'm still having problems absorbing vitamins and found out that I don't absorb zinc or folic acid, along with my malabsorption of B12. It caused a sluggish thyroid, among other problems. It might be that I have a problem with dairy. After a 3-month trip to China, my digestion improved ten-fold and I realized that I don't consume milk products there, aside from chocolate. So I cut most dairy from my diet and my digestion improved, though I'm not yet sure about the malabsorption. But I'm confused as to the root of the problem. My main symptom with dairy appears to be constipation- but I'm having severe fatigue issues as well (though that might be my battle with the thyroid.)

I suppose my main questions are:

1. Can casein cause a similar immunological reaction in the same way gluten would for Celiacs (meaning only needs to be absorbed into my bloodstream) or is it more like an intolerance and must go through my digestive tract?

2. My sublingual vitamins use lactose as a binder. Is it possible to separate lactose from casein?

I suppose I'm just confused about why Celiacs go on a casein-free diet to begin with if it doesn't cause a similar immune response. Is it merely an intolerance or is it something a little more sinister? I have several other food intolerances but they don't usually bother me unless I eat a lot of it. But I only need to lick an envelope with gluten on it to get sick.

I'm confused! Help!

  • 1 month later...

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



kitchen-chemist Newbie

After being gluten free for nearly 6 years, it turns out that I'm still having problems absorbing vitamins and found out that I don't absorb zinc or folic acid, along with my malabsorption of B12. It caused a sluggish thyroid, among other problems. It might be that I have a problem with dairy. After a 3-month trip to China, my digestion improved ten-fold and I realized that I don't consume milk products there, aside from chocolate. So I cut most dairy from my diet and my digestion improved, though I'm not yet sure about the malabsorption. But I'm confused as to the root of the problem. My main symptom with dairy appears to be constipation- but I'm having severe fatigue issues as well (though that might be my battle with the thyroid.)

I suppose my main questions are:

1. Can casein cause a similar immunological reaction in the same way gluten would for Celiacs (meaning only needs to be absorbed into my bloodstream) or is it more like an intolerance and must go through my digestive tract?

2. My sublingual vitamins use lactose as a binder. Is it possible to separate lactose from casein?

I suppose I'm just confused about why Celiacs go on a casein-free diet to begin with if it doesn't cause a similar immune response. Is it merely an intolerance or is it something a little more sinister? I have several other food intolerances but they don't usually bother me unless I eat a lot of it. But I only need to lick an envelope with gluten on it to get sick.

I'm confused! Help!

From what I've read, the protein structure of casein is similar enough to gluten to cause an immune response in some people. Considering that individuals make unique antibodies and not everyone reacts as severely, not all Celiac sufferers have a problem with dairy. Unfortunately, it seems that I do. I'm new to the the world of Celiac's, but I have a degree in chemistry, a minor in bio, and I'm in graduate school for medicinal chemistry. It helps being able to understand the molecular biology aspect. Lactose is a milk sugar that can be refined and, yes, separated from the protein portion of milk. Lactose intolerance is common among Celiac patients b/c of the damage to the small intestines, where the enzyme lactase is made. Some people, like my son, regain the ability to drink milk after going gluten-free. For me, lactose free/gluten-free dair still produced gluten-like symptoms, albeit milder than those from wheat.

So, in creative lay-man's terms:

Your antibodies are skeleton keys that match to gluten. If you are unlucky, then your key may also fit casein, but maybe not as well.

Not all casein is the same either. (cow, sheep, goat, etc) I haven't tried goat's milk or cheese yet, but plan to. I rather hope it's okay, b/c I'm very fond of dairy.

I hope this helps.

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      132,372
    • Most Online (within 30 mins)
      7,748

    cianb4121
    Newest Member
    cianb4121
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Russ H
      There were some interesting talks, particularly Prof Ludvig Stollid's talk on therapeutics for coeliac disease.    https://www.youtube.com/playlist?list=PLRcl2mPE0WdigRtJPvylUJbkCx263KF_t
    • Rejoicephd
      Thank you @trents for letting me know you experience something similar thanks @knitty kitty for your response and resources.  I will be following up with my doctor about these results and I’ll read the articles you sent. Thanks - I really appreciate you all.
    • knitty kitty
      You're right, doctors usually only test Vitamin D and B12.  Both are really important, but they're not good indicators of deficiencies in the other B vitamins.  Our bodies are able to store Vitamin B12 and Vitamin D in the liver for up to a year or longer.  The other B vitamins can only be stored for much shorter periods of time.  Pyridoxine B 6 can be stored for several months, but the others only a month or two at the longest.  Thiamine stores can be depleted in as little as three days.  There's no correlation between B12 levels and the other B vitamins' levels.  Blood tests can't measure the amount of vitamins stored inside cells where they are used.  There's disagreement as to what optimal vitamin levels are.  The Recommended Daily Allowance is based on the minimum daily amount needed to prevent disease set back in the forties when people ate a totally different diet and gruesome experiments were done on people.  Folate  requirements had to be updated in the nineties after spina bifida increased and synthetic folic acid was mandated to be added to grain products.  Vitamin D requirements have been updated only in the past few years.   Doctors aren't required to take as many hours of nutritional education as in the past.  They're educated in learning institutions funded by pharmaceutical corporations.  Natural substances like vitamins can't be patented, so there's more money to be made prescribing pharmaceuticals than vitamins.   Also, look into the Autoimmune Protocol Diet, developed by Dr. Sarah Ballantyne, a Celiac herself.  Her book The Paleo Approach has been most helpful to me.  You're very welcome.  I'm glad I can help you around some stumbling blocks while on this journey.    Keep me posted on your progress!  Best wishes! P.S.  interesting reading: Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/
    • NanceK
      So interesting that you stated you had sub clinical vitamin deficiencies. When I was first diagnosed with celiac disease (silent), the vitamin levels my doctor did test for were mostly within normal range (lower end) with the exception of vitamin D. I believe he tested D, B12, magnesium, and iron.  I wondered how it was possible that I had celiac disease without being deficient in everything!  I’m wondering now if I have subclinical vitamin deficiencies as well, because even though I remain gluten free, I struggle with insomnia, low energy, body aches, etc.  It’s truly frustrating when you stay true to the gluten-free diet, yet feel fatigued most days. I’ll definitely try the B-complex, and the Benfotiamine again, and will keep you posted. Thanks once again!
    • knitty kitty
      Segments of the protein Casein are the same as segments of the protein strands of gluten, the 33-mer segment.   The cow's body builds that Casein protein.  It doesn't come from wheat.   Casein can trigger the same reaction as being exposed to gluten in some people.   This is not a dairy allergy (IGE mediated response).  It is not lactose intolerance.  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.