Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Is It Possible To Test Negative Then Get A Positve

redheadsmom

Recommended Posts

redheadsmom Rookie
redheadsmom
Posted

The more research I have been doing over the last few weeks is all pointing to me having Celiac. I had blood tests done yesterday and am waiting for the results. I was tested for Celiac via blood work about 4-5 years ago and it was negative so I was wondering if it's possible to test negative and then a few years later test positive? I also had an endoscopy done about 5 years ago because I was having severe heartburn and was diagnosed with GERD and nothing was said about Celiac after the endoscopy. I'm actually hoping I test positive so everything I have been dealing with for 15 years makes sense!

Jessica

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


mushroom Proficient
mushroom
Posted

Yes it is completely possible to test negative earlier and positive later. The testing results are graded so that a small level of antibodies is negative, a moderate amount is mildly "positive" and everything over a certain number if positive. So you couldl have been in early stages when you were first tested and then become more reactive farther down the line, and hence now diagnosable. The testing process is not perfect by any means, and many gluten intolerants will never test positive to the current celiac tests but nevertheless cannot eat gluten. So even if your current tests are also negative, you should try eating gluten free and see if it works for you. :)

Roda Rising Star
Roda
Posted

Yes it is definately possible. My now 6 year old tested negative in Nov. 2008 after I was diagnosed. Fast forward two years and he tested positive in Nov. 2010.

Judy3 Contributor
Judy3
Posted

Raising hand... negative for years, positive in 2010

jemms Apprentice
jemms
Posted

Judy,

did you have to start eating gluten again for the results to show positive? Thanks!! :)

Judy3 Contributor
Judy3
Posted

Judy,

did you have to start eating gluten again for the results to show positive? Thanks!! :)

I didn't go gluten free until after the diagnosis in 2010, my initial tests still showed negative (not sure which ones) but my biopsies and genetic tests showed Celiac. So I went gluten free that day. In the past when they did the tests that came back negative I had been sick for a month or more and hadn't eaten much but cottage cheese and jello for a month so I was actually gluten free and didn't realize it.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      128,073
    • Most Online (within 30 mins)
      7,748
    David Croft
    Newest Member
    David Croft
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      70.6k
  • Celiac.com Sponsor (A22):



  • Who's Online (See full list)

    • There are no registered users currently online
  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • trents
      Celiac or Addison's complications? Can someone share their experience?

      By trents · Posted

      @KRipple, thank you for the lab results from your husband's celiac disease blood antibody testing. The lab result you share would seem to be the tTG-IGA (Tissue Transglutaminase IGA) and the test result is in excess of 10x normal. This is significant as there is an increasing tendency for physicians to grant a celiac disease diagnosis on the basis of antibody testing alone when the scores on that particular test exceed 10x normal. This trend started in the UK during the COVID pandemic when there was tremendous pressure on the medical system over there and it has spread to the USA. The tTG-IGA is the centerpiece of celiac disease blood antibody testing. All this to say that some doctors would grant a celiac disease diagnosis on your husband's bloodwork alone and not feel a need to go forward with an endoscopy with biopsy. This is something you and your husband might wish to take up with his physicians. In view of his many health issues it might be wise to avoid any further damage to his small bowel lining by the continuing consumption of gluten and also to allow healing of such to progress. The lining of the small bowel is the place where essentially all of our nutrition is absorbed. This is why celiac disease when it is not addressed with a gluten free diet for many years typically results in additional health problems that are tied to nutritional deficiencies. The millions and millions of tiny finger-like projections that make up the nutrient absorbing surface of the small bowel lining are worn down by the constant inflammation from gluten consumption. In celiac disease, the immune system has been tricked into labeling gluten as an invader. As these finger-like projections are worn down, the efficiency of nutrient absorption becomes more and more compromised. We call this villous atrophy.   
    • KRipple
      Celiac or Addison's complications? Can someone share their experience?

      By KRipple · Posted

      Thank you so much! And sorry for not responding sooner. I've been scouring the hospital records and can find nothing other than the following results (no lab info provided): Component Transglutaminase IgA   Normal Range: 0 - 15.0 U/mL >250.0 U/mL High   We live in Olympia, WA and I will be calling University of Washington Hospital - Roosevelt in Seattle first thing tomorrow. They seem to be the most knowledgeable about complex endocrine issues like APS 2 (and perhaps the dynamics of how APS 2 and Celiacs can affect each other). His diarrhea has not abated even without eating gluten, but that could be a presentation of either Celiac's or Addison's. So complicated. We don't have a date for endoscopy yet. I will let my husband know about resuming gluten.    Again, thank you so much for sharing your knowledge with me!
    • Jmartes71
      Celiac pain relief

      By Jmartes71 · Posted

      Ginger is my best friend, it helps alot with tummy issues..
    • aattana
      Positive gliadin (deamidated) IgG, normal everything else?

      By aattana · Posted

      Hi Phosphone, did you ever figure out what elevated your DGP?  I am in the same boat. 
    • trents
      Celiac or Addison's complications? Can someone share their experience?

      By trents · Posted

      Scott makes a good point about the prednisone. It has a general suppressing effect on the immune system. Don't misunderstand me. In view of your husband's several autoimmune afflictions, it would seem to be an appropriate medication therapy but it will likely invalidate endoscopy/biopsy test results for celiac disease.
×
×
  • Create New...