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Link To Diabetes?


redheadheather

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redheadheather Explorer

This is a spinoff from another post... I just saw someone posting that it is suspected that their child got diabetes because of undiagnosed celiac... does anyone know how this happens? Is it from the lack of nutrient absorption? I hadn't heard this before and an curious what the link is.

Thanks.

As a side note - DS's blood test results were in yesterday according to the nurse, but they couldn't give them to me as they hadn't been reviewed by a Dr. yet. She said I should get them today.

Heather


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lbsteenwyk Explorer

I don't know the science behind it, but I think this is simply because undiagnosed celiac disease makes people more susceptible to other autoimmune disorders - Type 1 diabetes is also an autoimmune disease. Between 3-8% of children with Type 1 diabetes also have celiac disease.

Guest Lucy

try 15-25% of kids with Type 1 diabets have celiac. My son being one of them. My sons Endocronologist thinks its probably even higher than that, but most kids are not tested for celiac.

Once you have one auto immune disease, your body becomes more suseptible to another. I was probably the one you saw the post from

Celiac runs in our family. Diabetes DOES NOT. NO ONE has type one diabetes in either side. My son has both. His Dr. is fairly certain that celiac weakened his body, so he developed Diabetes. There is more technical terminology, but a child who develops Type 1 diabetes is pre disposed, and something "triggers" it. A sickness or malnourishment of some kind. I am not a pro at explaining it yet. Hope this helps.

lbsteenwyk Explorer

Lucy:

Do you have a reference for those numbers? I don't doubt, it's true, but I try keep up with current research so I can share it with docs I work with. I'm always advocating to get type 1 diabetics tested for celiac disease, so if I have a reference to current research that indicates the numbers are this high, it would really help. THanks!

Guest Lucy

I don't remember who told me, if it was the diabetes nurse educator or his endocronologist? I will try to find out. I'm pretty sure it was his endocronologist. He is from India, and tested him within a month of his diagnosis of diabetes, for celiac. He seems to think it is extremely common. We don't have another appointment for 2.5 months, but occasionally talk to him on the phone. He is extremely nice, but busy, so I'll ask next time we talk.

lbsteenwyk Explorer
I don't remember who told me, if it was the diabetes nurse educator or his endocronologist?  I will try to find out.  I'm pretty sure it was his endocronologist.  He is from India, and tested him within a month of his diagnosis of diabetes, for celiac.  He seems to think it is extremely common.  We don't have another appointment for 2.5 months,  but occasionally talk to him on the phone.  He is extremely nice, but busy,  so I'll ask next time we talk.

<{POST_SNAPBACK}>

Thanks, Lucy; I'll appreciate any information you can get. In the meantime, I'll try doing a literature search and see what I come up with. If I find anything interesting, I'll let you know.

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    • trents
      I would ask the GI doc about the elevated IGA score of 401. That one is what we commonly refer to as "total IGA" and also known as "Immunoglobulin A (IgA)". It could be nothing but it can also indicate some other health issues, some of them serious in nature. I would google potential causes for that if I were you. Also, if there is a chance the GI doc will want to do more testing for celiac disease, either antibody testing or an endoscopy with biopsy, you should not cut back on gluten consumption until all celiac disease testing is done. Otherwise, you will invalidate the testing.
    • shell504
      Hello. I apologize. I didn't know there wasn't a standard.  The standard listed  for the IGA is normal range 47-310.  The others were all listed as <15.0 u/l is antibody not detected and 15> antibody is detected.  And the negative one the standard is negative.  It is a normal PCP dr. I do have a second opinion appt scheduled with a GI specialist in 2 weeks. Honestly, I haven't cut out gluten at all. I just switched to whole fibers and everything has been getting better. She wanted to do the test just to check, which I was fine with. We'll see what the GI dr says. Thank you for commenting. 
    • trents
      It is also possible that since eating the fries you have been glutened again during the week. I would double check the food in your cupboard and reread the ingredient lists. Food companies can and do change their formulations from time to time such that something that used to be gluten free is no more. What I am saying is, don't assume the distress you are experiencing comes from one incident of glutening. There could, coincidentally, be another one on it's heels. 
    • trents
      Welcome to the forum, @shell504! The IGA 401mg/dl is not a test for celiac disease per se but a check to see if you are IGA deficient. People who are IGA deficient will produce celiac blood test antibody scores that are artificially low which can result in false negatives for the individual antibody tests such as the TTG IGA. You did not include reference ranges along with the test scores and since each laboratory uses custom reference range scales, we cannot comment with certainty, but from the sheer magnitude of the IGA score (401) it does not look like you are IGA deficient. And since there are no annotations indicating that the other test scores are out of range, it does not appear there is any antibody evidence that you have celiac disease. So, I think you are warranted in questioning your physician's dx of celiac disease. And it is also true that a colonoscopy cannot be used to dx celiac disease. The endoscopy with biopsy of the small bowel is the appropriate procedure for diagnosing celiac disease. But unless there is a positive in the antibody testing, there is usually no justification for doing the endoscopy/biopsy. Is this physician a PCP or a GI doc? I think I would ask for a second opinion. It seems as though this physician is not very knowledgeable about celiac disease diagnositcs. Having said all that, it may be that you suffer from NCGS (Non Celiac Gluten Sensitivity) rather than celiac disease. The two gluten disorders share many of the same GI symptoms. The difference is that NCGS does not damage the villous lining of the small bowel as does celiac disease. NCGS is 10x more common than celiac disease. The antidote for both is complete abstinence from gluten. Some experts believe NCGS can be a precursor to the development of celiac disease. There is not test for NCGS. Celiac disease must first be ruled out. So, if it becomes apparent that gluten is causing distress and testing rules out celiac disease, then the diagnosis would be NCGS. Hope this helps. 
    • shell504
      I apologize i can't figure out how to get the picture on here.  Results were: IGA 401mg/dl Deamidated Gliadin IGG. <1.0 Deamidated Gliadin IGA. <1.0 Tissue Transglutaminase IGA AB. <1.0 Endomysial IGA. Negative.  Is she just going based off of the IGA alone? And because that is elevated, it's positive? The test states: "Results do not support a diagnosis of celiac disease." 
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