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New Diagnosis?


clbaug9

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clbaug9 Newbie

I was tested for celiac disease recently after asking my doctor for the labwork. The endomysial IgA, gliadin IgA, and tissue transglutaminase IgA were normal. The Gliadin IgG antibody was high. She said this was a positive diagnosis for celiac disease. I would like more information. She is kind of laidback and I just want to know if this is definately celiac disease, or if it is possibly something else?


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KaitiUSA Enthusiast

Did you have the total serum IgA run? That is used to rule out IgA deficiency which can make the IgA tests come back negative when they would otherwise be positive.

The IgG is the least specific test of the bunch. IgG detects a problem with gluten and it is usually one of the first things to go high.

I can't tell you whether or not you have it though, thats something to talk to your doctor about because I am only hearing a little bit of info and not the bigger picture. You very well could have it.

Rachel--24 Collaborator

I agree with Kaiti...you should talk to your doctor about this...maybe run more tests. I was reading something yesterday which said that if all blood tests are normal with only the IgG being elevated this *could* be caused by something else other than celiac disease. The article stated that other intestinal conditions could also cause an elevated IgG. Of course it could still be celiac disease or intolerance so it should probably be further looked into.

clbaug9 Newbie

thanks, for answering. They did not do a total IgA test, so I don't know that. What exactly is the difference between celiac disease and gluten intolerance? My doctor is more of the type to say if you feel better not eating gluten, then don't eat gluten. I have a hard time getting her to do more investigation.

KaitiUSA Enthusiast
thanks, for answering. They did not do a  total IgA test, so I don't know that. What exactly is the difference between celiac disease and gluten intolerance? My doctor is more of the type to say if you feel better not eating gluten, then don't eat gluten. I have a hard time getting her to do more investigation.

<{POST_SNAPBACK}>

Celiac has damaged caused by gluten. A gluten intolerance but not celiac usually does not have the damage with it. There has been debate about whether or not someone with gluten intolerance without a celiac gene can get celiac and I think that is possible if someone does not follow the diet. Your body will eventually snap and say thats enough.

Have you had a gene test done? That may help shed some light.

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    • trents
      Take it easy! I was just prompting you for some clarification.  In the distillation process, the liquid is boiled and the vapor descends up a tube and condenses into another container as it cools. What people are saying is that the gluten molecules are too large and heavy to travel up with the vapor and so get left behind in the original liquid solution. Therefore, the condensate should be free of gluten, no matter if there was gluten in the original solution. The explanation contained in the second sentence I quoted from your post would not seem to square with the physics of the distillation process. Unless, that is, I misunderstood what you were trying to explain.
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      No they do not contradict each other. Just like frying oil can be cross contaminated even though the oil doesn't contain the luten protein. The same is the same for a distilled vinegar or spirit which originally came from a gluten source. Just because you don't understand, doesn't mean you can tell me that my sentences contradict each other. Do you have a PhD in biochemistry or friends that do and access to a lab?  If not, saying you don't understand is one thing anything else can be dangerous to others. 
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      The reason that it triggers your dermatitis herpetiformis but not your celiac disease is because you aren't completely intolerant to gluten. The celiac and dermatitis herpetiformis genes are both on the same chronometer. Dermatitis herpetoformus reacts to gluten even if there's a small amount of cross contamination while celiac gene may be able to tolerate a some gluten or cross contamination. It just depends on the sensitivity of the gene. 
    • trents
      @Mynx, you say, "The reason this is believed is because the gluten protein molecule is too big to pass through the distillation process. Unfortunately, the liquid ie vinegar is cross contaminated because the gluten protein had been in the liquid prior to distillation process." I guess I misunderstand what you are trying to say but the statements in those two sentences seem to contradict one another.
    • Mynx
      It isn't a conjecture. I have gotten glitened from having some distilled white vinegar as a test. When I talked to some of my scientists friends, they confirmed that for a mall percentage of people, distilled white vinegar is a problem. The cross contamination isn't from wheat glue in a cask. While yhe gluten protein is too large to pass through the distillation process, after the distillation process, the vinegar is still cross contaminated. Please don't dismiss or disregard the small group of people who are 100^ gluten intolerant by saying things are conjecture. Just because you haven't done thr research or aren't as sensitive to gluten doesn't mean that everyone is like you. 
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