Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Oral And Rectal Challenge Testing Of The Mucosa

ravenwoodglass

Recommended Posts

ravenwoodglass Mentor
ravenwoodglass
Posted

There has been some recent debate on whether gluten is absorbed into the system through any mucosa other than the intestines. In the US mucosal testing is unheard of they would rather make us sick for weeks or months to do an expensive and inherently risky endo and biopsy. Other countrys have found that that torture may not be needed and that by using a gluten laden patch or infusion or suppository that the histological changes can be detected in the mucous membranes within a relatively short time. There are many more articles out there a search of rectal or mucosal challenge and celiac will bring them up.

Here is one study on the use of detecting celiac through rectal mucosa challenge off of Pub Med

Open Original Shared Link

And another

Open Original Shared Link

And one last one on nasal mucosa testing

Open Original Shared Link

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Nancym Enthusiast
Nancym
Posted

None of those links worked for me!

psawyer Proficient
psawyer
Posted

Those links appeat to have been pasted in from another thread:

Open Original Shared Link

They work there, but long urls are displayed with an elipsis replacing a number of characters in the middle. If the displayed version is pasted, it does not work.

ravenwoodglass Mentor
ravenwoodglass
Posted
  • Author
Those links appeat to have been pasted in from another thread:

Open Original Shared Link

They work there, but long urls are displayed with an elipsis replacing a number of characters in the middle. If the displayed version is pasted, it does not work.

They were pasted and I did not realize they would not open after pasting. I'll see if I can correct that. Thanks for posting the link to the other post.

One real good reason for us to get this info out is it would be nice if US doctors knew about some of the less invasive forms of testing and hopefully if people ask their GI doctors about it and show them some of the studies on the validity of mucosal testing we can get it used in the US and more people will be able to be diagnosed without having to be made ill to do so.

Edit I think I was able to fix the problem. Thanks guys seems the world forces me to be more computer literate every day, whether I want to or not.

  • 4 years later...
domesticactivist Collaborator
domesticactivist
Posted

I just had someone tell me about Cyrex labs cross-reactivity tests and when I went to their site saw that they offer Mucosal Gluten Reactivity Screen that I'd seen mentioned here on this site a couple times. I'm very interested to learn more about this.

Open Original Shared Link

Does anyone have neutral information on the validity of the Cyrex labs tests?

Skylark Collaborator
Skylark
Posted

Does anyone have neutral information on the validity of the Cyrex labs tests?

That's just salivary IgA. It's no better validated than fecal.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      126,109
    • Most Online (within 30 mins)
      7,748
    Cris B
    Newest Member
    Cris B
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      120.9k
    • Total Posts
      69.2k
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • StaciField
      My bone structure is disintegrating and I’m having to have my teeth removed

      By StaciField · Posted

      There’s a Cosco in Auckland in New Zealand. It’s a bit away from where I live but it’s worth the travel for me. Very appreciative of your advice.
    • Wheatwacked
      Celiac Maybe a Possibility?

      By Wheatwacked · Posted

      It seems you have proven that you cannot eat gluten.  You've done what your doctors have not been able to do in 40 years. That's your low vitamin D, a common symptom with Celiac Disease.  Zinc is also a common defiency.  Its an antiviral.  that's why zinc gluconate lozenges work against airborne viruses.  Vitamin D and the Immune System+ Toe cramps, I find 250 mg of Thiamine helps.   When I started GFD I counted 19 symptoms going back to childhood that improved with Gluten Free Diet and vitamin D. I still take 10,000 IU a day to maintain 80 ng/ml and get it tested 4 times a year. Highest was 93 ng/ml and that was at end of summer.  Any excess is stored in fat or excreted through bile.   The western diet is deficient in many nutrients including choline and iodine.  Thats why processed foods are fortified.  Celiac Disease causes malabsorption of vitamins and minerals from the small intestine damage.  GFD stops the damage, but you will still have symptoms of deficiency until you get your vitamins repleted to normal.  Try to reduce your omega 6:3 ratio.  The Standard American Diet is 14:1 or greater.  Healthy is 3:1.  Wheat flour is 22:1.  Potatoes are 3:1 while sweet potatoes are 14:1.  So those sweet potatos that everyone says is better than Russet: they are increasing your inflammation levels.   
    • Scott Adams
      Weird Symptoms

      By Scott Adams · Posted

      My mother also has celiac disease, and one of her symptoms for many years before her diagnosis was TMJ. I believe it took her many years on a gluten-free diet before this issue went away.
    • Jeff Platt
      Weird Symptoms

      By Jeff Platt · Posted

      Ear pain and ringing your entire life may or may not be TMJ related but could be something else. A good TMJ exam would be helpful to rule that out as a potential cause from a dentist who treats that. I have teens as well as adults of all ages who suffer from TMJ issues so it’s not a certain age when it shows up.   
    • cristiana
      Weird Symptoms

      By cristiana · Posted

      Not sure if related to coeliac disease but my ear ringing  has stepped up a notch since diagnosis.  Even since a child silence really hurts my ears - there is always a really loud noise if there is no other noise in a quiet room - but my brain has learned to filter it out.  Since diagnosis in my forties I also get a metallic ringing in my ears, sometimes just one, sometimes both.  But it comes and goes.   My sister also suffers now, we are both in our fifties, but she is not a coeliac, so for all I know it could just be an age thing.  I do get occasional stabbing pain in my ears but that has been all my life, and I do appear to be vulnerable to outer ear infections too.  So not a particularly helpful reply here, but I suppose what I am trying to say is it might be related but then again it could just be one of those things.   I think in the UK where I live doctors like you to report if you get tinnitus in just the one ear.  I reported mine but no cause was found.  Most of the time it is nothing but sometimes it can have a cause that can be treated, so perhaps worth reporting to your GP.  
×
×
  • Create New...