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    • trents
      Concerning the EMA positive result, the EMA was the original blood test developed to detect celiac disease and has largely been replaced by the tTG-IGA which has a similar reliability confidence but is much less expensive to run. Yes, a positive EMA is very strong evidence of celiac disease but not foolproof. In the UK, a tTG-IGA score that is 10x normal or greater will often result in foregoing the endoscopy/biopsy. Weaker positives on the tTG-IGA still trigger the endoscopy/biopsy. That protocol is being considered in the US but is not yet in place.
    • trents
      Welcome to the celiac.com community, @mike101020! First, what was the reference range for the ttg-iga blood test? Can't tell much from the raw score you gave because different labs use different reference ranges. Second, there are some non celiac medical conditions, some medications and even some non-gluten food proteins that can cause elevated celiac blood antibodies in some individuals. The most likely explanation is celiac disease but it is not quite a slam dunk. The endoscopy/biopsy is considered the gold standard for celiac disease diagnosis and serves as confirmation of elevated blood antibody levels from the blood testing.
    • Wheatwacked
      Vitamin D status in the UK is even worse than the US.  vitamin D is essential for fighting bone loss and dental health and resistance to infection.  Mental health and depression can also be affected by vitamin D deficiency.  Perhaps low D is the reason that some suffer from multiple autoimmune diseases.  In studies, low D is a factor in almost all of the autoimmune diseases that it has been studied in. Even while searching for your diagnosis, testing your 25(OH)D status and improving it my help your general wellness. Vitamin D Deficiency Affects 60% in Britain: How to Fix It?    
    • mike101020
      Hi, I recently was informed by my doctor that I had scored 9.8 on my ttgl blood test and a follow up EMA test was positive.   I am no waiting for a biopsy but have read online that if your EMA is positive then that pretty much confirms celiac. However is this actually true because if it it is what is the point of the biopsy?   Thanks for any help 
    • lil-oly
      Hey there, have you been tested for allergies? You may not only have celiac disease but be allergic. I have celiac disease and am allergic to Barley, wheat and rye. 
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