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Altoma

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  1. Astonishing is that you with such complains and positive family for celiac and you did not get biopsy testing. I would recommend that even with negative blood tests. The risk of celiac in family members is around 8-10%and this is very high compared to 1% general risk. Having hypothyroid increases the chance of having celiac further. See this on family...
  2. Celiac disease, if confirmed by biopsy, is the most likely cause of osteoporosis even if the patient does not have diarrhea. The risk of having osteoporosis correlates with the severity of small bowel histological change. Furthermore, the mechanism of osteoporosis relates to some inflammatory mediators causing depletion of bone calcium. See this...
  3. Yes, you still need endoscopy and biopsy because you do not have symptoms and the level of antibodies is not clearly discriminative, it is borderline positive. https://doi.org/10.1177/2050640619844125 https://www.ueg.eu/quality-of-care/guidelines/ Al-toma, consultant gastroenterologist
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