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Russ H

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Celiac.com - Celiac Disease & Gluten-Free Diet Support Since 1995

Everything posted by Russ H

  1. Russ H
    I would be interested to see these. Do you have the references?
  2. Russ H
    DGP on its own is fairly good at predicting coeliac disease but it would usually be accompanied by high tTG2. DGP with low tTG2 is not very predictive of coeliac disease. There is a larger study linked below which indicates a positive predictive value of 2.8% in paediatric patients for isolated DGP. https://www.sciencedirect.com/science/article...
  3. Russ H
    Yes tTG2 antibodies 10x the reference range is almost certainly coeliac. Add in stage 3 viillous atrophy and well... EMA also detects tTG2 antibodies but is an old and relatively crude and insensitive test.
  4. Russ H
    DGP is part of the standard coeliac blood screening panel. It gives a small increase in predictive value. The fact that the other 2 tests showed very low levels of antibodies combined with a lack of symptoms suggests that this is not coeliac disease.
  5. Russ H
    Isolated DGP IgG as in this case has poor predictive value (only a few percent). https://onlinelibrary.wiley.com/doi/10.1111/jpc.16071 Based on the results and symptoms, I think it is unlikely to be coeliac disease (although this does not rule it out).
  6. Russ H
    That sounds like a dysbiosis which is common with coeliac disease. You get bacterial overgrowth in the small intestine which produces gas and probably toxic by-products that get into the bloodstream. We call it SIBO (small intestine bacterial overgrowth). For people with coeliac disease it generally corrects itself on a strict gluten-free diet. Mine took...
  7. Russ H
    OK, so it does not sound like diabetes. Do you experience a swollen upper abdomen after eating and burping?
  8. Russ H
    And this occurs after you eat? Have you had your blood sugar tested? Do you experience bloating and burping after eating?
  9. Russ H
    I understand now. When you say ataxia, you mean that your have difficulty co-ordinating your muscle movements (such as difficulties with speech or walking)?
  10. Russ H
    Emanon, you need to have a blood test for coeliac disease. For this test to be accurate, you need to eat gluten every day for 6 weeks prior to the test. Can you get your doctor to give you a blood test? The test is for IgA tTG2 antibodies - it is an easy test to do.
  11. Russ H
    It is very common for adults to have neurological symptoms on diagnosis of coeliac disease. Most people show clinical improvement by a year, so be patient and adhere to a strict gluten-free diet. Take a good multivitamin for the first year at least.
  12. Russ H
    Hi IanL, Do you have coeliac disease, and is the bakery gluten-free?
  13. Russ H
    That is interesting. UV is also used to treat psoriasis that won't respond to other treatments.
  14. Russ H
    Hello lavranso4, Your don't say what your sex is. It is common for men with untreated coeliac disease to experience androgen resistance where the body tissues stop responding to testosterone. Typically people will show raised blood levels of free testosterone but reduced levels of dihydrotestosterone (DHT). There may also be increased levels of luteinising...
  15. Russ H
    It is quite common to experience neurological symptoms with coeliac disease, particularly anxiety and short term memory problems. I used to drink in the same way as it provides rapid relief from the symptom of anxiety.
  16. Russ H
    How do you mean basic screening? The basic test for coeliac disease is a blood test for IgA tTG2 antibodies. If you have chronic gastrointestinal symptoms, that should be reason enough for a test. Without units and the lab reference range it is not possible to evaluate the results you have supplied. I assume it is grams per litre, so it is high normal for...
  17. Russ H
    There is an association between coeliac disease and IgE mediated food allergy. https://journals.lww.com/jpgn/Abstract/2023/01000/Celiac_Disease_Frequency_Is_Increased_in.9.aspx It does not seem well understood currently. Have you looked at things like shower gel, shampoo and clothes washing detergent? I have become quite allergic to certain brands...
  18. Russ H
    Yes, and this is a contributing factor to why gluten-free bread is so expensive - restricted supply chain, testing and small volumes. Apart from xanthan gum, some gluten-free breads use psyllium, and most use rice flour. It is more likely a reaction to one of these than gluten contamination.
  19. Russ H
    I did a quick search and found a couple of cases of transverse myelitis associated with coeliac disease, so it is not unheard of. I had a heart arrhythmia that has gone since I was diagnosed. I also used to get bad chilblains, which are also associated with autoimmune antibodies. How are you getting on?
  20. Russ H
    This suggests 1 in 7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155080/
  21. Russ H
    It would be nice to have some references for these claims. Sunburn in childhood is the greatest risk for skin cancer: https://www.nhs.uk/conditions/melanoma-skin-cancer/causes/ UV exposure is responsible for 80% of skin ageing: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790843/ If you believe that vitamin D levels need to be raised...
  22. Russ H
    According to UK NICE guidelines for coeliac disease, IgA deficiency is defined as total IgA less than 0.07 g per litre. Yours are not low enough to affect the result by this guidance. What leads you to suspect that you may have coeliac disease?
  23. Russ H
    Isolated IgG DGP antibodies are not very specific for coeliac disease. In people under the age of 18, has a positive predictive value (PPV) of about 3% The small study below estimates a PPV of between 2.3% and 51.8% in adults (the large uncertainty is due to the small size of the study). https://celiacdiseasecenter.columbia.edu/wp-content/uploads/20...
  24. Russ H
    Yes, but it isn't clear when the tests and diet were performed and how strict the diet was. I only have brown rice in the cupboard.
  25. Russ H
    There are 3 overlapping conditions with a similar aetiology: coeliac disease, dermatitis herpetiformis and gluten induced neuropathy (aka gluten ataxia). You can have them together or individually. They all involve making antibodies to a class of enzymes in the body called tissue transglutaminase (tTG). Classical coeliac disease involves making antibodies...
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