knitty kitty

@ceslater,

Ask your doctor for an Erythrocyte Transketolase test to check for Thiamine deficiency.  Although, you can have normal blood levels and still have a clinical thiamine deficiency.  

Palpitations, irregular heartbeat, and migraines are associated with Thiamine deficiency.  Weight loss (without trying) is another symptom.  Dry eyes are associated with Thiamine deficiency.  Diabetes is associated with Thiamine deficiency, too.  About 96% of people with diabetes have Thiamine deficiency.  

I had all of these symptoms of Thiamine deficiency.  My doctors didn't recognize Thiamine deficiency in a non-alcoholic.  Doctors are not required to take much nutritional education while at med school.  Still, check with your doctor about supplementing with B Complex, Vitamin D and magnesium in addition to Thiamine.  Benfotiamine really helped me.  

Thiamine deficiency disorders: a clinical perspective

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451766/

Thiamine and benfotiamine: Focus on their therapeutic potential

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682628/

Benefits of Supplementing with B Complex

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316433/

Keep us posted on your progress!

@ALLAN HUGHES,

Are you taking any nutritional supplements?  

Several of the B vitamins are needed to make red blood cells.  Celiac and aging can affect our ability to absorb nutrients from food.  Supplementing with a B Complex may help.

Riboflavin B 2 has been shown to promote erythropoiesis.  Niacin B 3, Thiamine B1, Vitamin D, and Pyridoxine B 6 are also required, in addition to Folate and Cobalamine B12.  Copper is needed as well as iron.  

Talk to your doctor about boosting your ability to absorb nutrients by taking a B Complex, Vitamin D and copper.  

Hope this helps!

Welcome to the forum, @GJC!

No, Celiac doesn't go away.  With us, every time we eat gluten, our immune system revs up, increasing inflammation and causing collateral damage.  

Every time we eat gluten, antigluten antibodies attack the gluten, but also the cells of our bodies.  In the stomach, the parietal cells produce the Intrinsic Factor which binds to Vitamin B12 so B12 can then be absorbed in the small intestine.  When damaged by the antibodies, parietal cells cannot make the Intrinsic Factor and B12 doesn't get absorbed.  If we become depleted in B12, we cannot make healthy red blood cells and this can cause B12 deficiency anemia.  Fatigue can be a symptom of low B12 or B12 deficiency anemia.  

Those antigluten antibodies also damage the villi lining the small intestine.  The villi absorb nutrients from our food, sort of like anemones filtering seawater.  Damaged villi cannot absorb essential nutrients from our food and we can develop nutritional deficiencies.  Malnutrition is the collateral damage.  Our body cannot function properly if it doesn't have enough nutrients.  

We need the eight essential B vitamins, Vitamin C, and four fat soluble vitamins, A, D, E and K, and minerals, like calcium, iron, magnesium, zinc and a bunch of trace minerals.  Iron deficiency can cause iron deficiency anemia which results in fatigue.  Deficiencies in any of the eight B vitamins can cause fatigue.

Vitamin D regulates the immune system, lowers inflammation, and helps produce hormones.  Vitamin D is important in developing bone density especially in the late teens to early twenties.  Consequences of not absorbing sufficient Vitamin D can result in osteopenia and osteoporosis when older.  Low Vitamin D can also result in hair loss, depression, menstrual irregularities, obesity and fatigue.  

Our body can make its own opioids.  That's why your toe quits hurting after you stub it.  We have opioid receptors throughout our body, including in our digestive system.  Gluten can attach to the opioid receptors in our digestive system.  We also have opioid receptors in our brains.  Gluten that escapes from our digestive tract into the bloodstream can attach to these brain receptors resulting in brain fog and fatigue.  These opioid receptors in the brain don't work the same in very young children as in adults.  This explains why you don't have tummy aches like a three year old. 

Take care of your future self by eating a healthy nutrient dense diet now.  Count your blessing that you were diagnosed so early in life.  

It can be tough, but we'll be cheering you on!  

Best wishes

@Liquid lunch,

Remember to stay away from cruciferous vegetables, for a while, too!!!  😺

Welcome to the forum, @LouisaM!

Taking Thiamine supplements helps with menstrual pain and irregularities.  Other vitamins like Riboflavin B2, Pyridoxine B6 and Niacin B3, and Vitamin D work with Thiamine and helped improve symptoms.

Even on a gluten free diet, Celiac people can develop nutritional deficiencies.  Discuss nutritional supplementation with your doctor and nutritionist.

References:

Nutritional Imbalances in Adult Celiac Patients Following a Gluten-Free Diet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398893/

The Effects of Vitamin B1 on Ameliorating the Premenstrual Syndrome Symptoms

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825494/

The Effect of Micronutrients on Pain Management of Primary Dysmenorrhea: a Systematic Review and Meta‐Analysis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146731/

Menstrual cycle symptoms are associated with nutrient intake: Results from network analysis from an online surve

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350787/

Hope this helps!  

Have you tried soaking them in distilled water?  Apparently distilled water can pull more lectins out of seeds and beans.

https://pubmed.ncbi.nlm.nih.gov/29580532/

Came across this article....

Mild metabolic hyperoxaluria and its response to pyridoxine

https://pubmed.ncbi.nlm.nih.gov/3811039/

Welcome to the forum, @ceslater!

Have you had your thyroid and parathyroid glands checked?

Apparently there's a link between Celiac disease and hyperparathyroidism and  mandibular tori.  

Magnesium is important for keeping calcium in the bone in place and not depositing elsewhere.  

Vitamins and minerals important to bone maintenance include Thiamine, Riboflavin, Pyridoxine, selenium and magnesium, as well as calcium and Vitamin D.  

References:

Celiac disease and primary hyperparathyroidism: an infrequent association

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10851394/

Coeliac disease and primary hyperparathyroidism: an association?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653933/

Hyperparathyroidism in dentistry: Issues and challenges!!

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911858/

Short-term oral magnesium supplementation suppresses bone turnover in postmenopausal osteoporotic women

https://pubmed.ncbi.nlm.nih.gov/19488681/

@DMulder47,

Many of the symptoms you describe are attributable to vitamin deficiencies.  Most people with Celiac Disease develop them because of the malabsorption and inflammation caused by celiac disease.

My heart palpitations and high heart rate were caused by a deficiency in Thiamine B1.  I had all the tests, too, and the doctors couldn't find anything.  POTS (Postural Orthistatic Tachycardia Syndrome) is caused by Thiamine deficiency.  Difficulty swallowing and nausea, migraines, ADHD and that extreme fatigue are all symptoms of Thiamine deficiency.  Blood tests can show blood levels within "normal" range, but you can still have a thiamine deficiency.  Thiamine is used inside cells.  A deficiency in Thiamine inside cells is not reflected in blood levels.  

Thiamine needs the other B vitamins and magnesium to work properly, so those need to be supplemented as well as other vitamins and minerals that are frequently low, Vitamin D and magnesium.

A combination of Thiamine, Riboflavin, Niacinamide, Pyridoxine, and Pantothenic Acid B 5 have been shown to help hemorrhoids.

@McNish,

Loss of Potassium is common in Thiamine deficiency.  This article explains...

https://www.hormonesmatter.com/thiamine-deficiency-causes-intracellular-potassium-wasting/

Anxiety is another symptom of Thiamine deficiency.

@Heather Fisher,

Constipation is an early symptom of Thiamine deficiency.  Thiamine improves brain function and helps clear that brain fog.  Thiamine relieves the fatigue.

High lipids are a symptom of Niacin B3 deficiency.  Niacin has been used by doctors to lower high lipid levels for over fifty years.  

Talk to your doctor and nutritionist about supplementing with vitamins and minerals.  Even if you have been on the gluten free diet, you can still develop nutritional deficiencies. 

 Thiamine deficiency disorders: a clinical perspective

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451766/

Keep us posted on your progress!

@ArchieK,

If you're eating a lot of processed carbohydrates, you may have Small Intestinal Bacterial Overgrowth (SIBO).  

These bacteria produce lots of gas after helping themselves to your carbohydrates.  They can spread from the large intestine (where they are supposed to be) into the small intestine where they can cause gastrointestinal symptoms and lots of gas. 

I chose a Paleo diet (no carbs) so that the carbohydrate loving bacteria would be starved out and beneficial bacteria could grow instead.  Beneficial probiotics after starving out the SIBO bacteria helps replenish beneficial bacteria.

Hope this helps!

P.S. Adding an article about SIBO...

https://www.hormonesmatter.com/sibo-ibs-constipation-thiamine-deficiency/

@Ginger38,

I was diagnosed with Generalized Anxiety Disorder and Complex PTSD.  SSRIs did not improve my health.  SSRIs made my gastrointestinal symptoms much much worse, worsening my brain health as well.  

What did work for me was to focus on calming my digestive system and providing essential vitamins and minerals so my body could function properly.  I followed a low histamine Paleo diet, and I took vitamin and mineral supplements.  I studied Nutrition before earning a degree in Microbiology, so I did research into healing my digestive system and improving my mental health. 

High histamine levels cause anxiety and inflammation.  Our bodies produce histamine in autoimmune reactions.  There is histamine in the food we eat.  If we reduce the amount of high histamine foods, reduce inflammation, and provide sufficient vitamins and minerals our bodies can clear histamine and heal.  Omega Threes, Vitamin D, the eight essential B vitamins, Vitamin C and minerals like magnesium all help to reduce histamine levels, reduce inflammation and promote healing.  

Serotonin is made in the intestinal tract.  Tryptophan is required to make Serotonin.  1000 mg of Tryptophan, some Pyridoxine B 6, Niacinamide B3, and magnesium an hour before bedtime has been found to promote Serotonin production, improve restful sleep and relieves anxiety.  Passion flower extract is beneficial in relieving anxiety and promoting restful sleep, too.

Benfotiamine (a form of Thiamine B1) has been shown to help heal the digestive tract and relieve anxiety.  

If you give the body the nutrients it needs, it can operate properly.  Your body can't make sufficient Serotonin if your digestive system is not absorbing nutrients because of celiac disease and inflammation.  Pharmaceuticals are a temporary bandaid and the side effects only make matters worse.

Please try Tryptophan now before starting an SSRI.  SSRIs cause further damage to the intestines.  Tryptophan has no harmful effects.  

KK

References:

Factors associated with villus atrophy in symptomatic coeliac disease patients on a gluten-free diet

https://pubmed.ncbi.nlm.nih.gov/28220520/

Antidepressant-like Effects of Representative Types of Food and Their Possible Mechanisms

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10574116/

Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728667/

The Effects of Dietary Tryptophan on Affective Disorders

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393508/

Effect of Tryptophan, Vitamin B6, and Nicotinamide-Containing Supplement Loading between Meals on Mood and Autonomic Nervous System Activity in Young Adults with Subclinical Depression: A Randomized, Double-Blind, and Placebo-Controlled Study

https://pubmed.ncbi.nlm.nih.gov/31902864/

Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959081/

Nutrition as Metabolic Treatment for Anxiety

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907178/

Vitamin B6: A new approach to lowering anxiety, and depression?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577631/

Thiamine and benfotiamine: Focus on their therapeutic potential

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682628/

Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459027/

Hiding in Plain Sight: Modern Thiamine Deficiency

Chandler Marrs and Derrick Lonsdale

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533683/

Welcome to the forum, @Gini1!

You can take a DNA test to see if you have any of the known genes for Celiac Disease.  

Anemia, diabetes, and thiamine deficiency can cause false negatives on serum tests.  Seronegative Celiac Disease does exist, where people with Celiac Disease don't show anti gluten antibodies in their blood.  

Other blood tests include the DGP IgA and IgG and the EMA IgA, but these depend on you having to eat a lot of gluten for several months  to get them to show up.  

The amount of gluten that you were eating prior to your "normal" tTg IgA test result could have caused the false negative.  Some people try a gluten free diet before going to their doctor.  About ten grams of gluten a day is needed to produce antibodies and villous damage.

Hope this helps!

Pumpkin seeds are high in Lectins.  Lectins are carbohydrate-binding proteins found in plant seeds and beans.  Lectins can be inflammatory to already damaged intestines as in Celiac Disease.  

Interesting Reading...

Do dietary lectins cause disease?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1115436/

@augustmoon,

No worries, we talk about poop a lot here.  

Are you currently eating gluten?  Or have you gone gluten free?

Do you eat a lot of carbohydrates?

Were you eating lots of gluten prior to your Celiac test? 

What symptoms made you get a Celiac test?  

Was the H. Pylori test negative?

Have you been tested for intestinal parasites?

Do you have constipation?  Is this with every bowel movement?

What have you been eating?  Are you eating gluten?

Welcome to the forum!

Do you have anemia or Diabetes? Thiamine and magnesium deficiencies can cause constipation. 

Are you keeping a food mood poo'd journal?  Do you know which food is causing the peach pit problem?  

Have you been checked for H. Pylori infection?

Welcome to the forum, @Lina0206!

Have you been checked for nutritional deficiencies?  Many newly diagnosed have low levels of Vitamin D which helps regulate the immune system and being low can cause dizziness, as can being low in some of the B Complex vitamins, like Cobalamine B12 and Thiamine B1.  

Have you talked to your doctor or nutritionist about supplementing with a B Complex supplement and Vitamin D to boost your absorption of these essential vitamins?

Since malabsorption occurs in Celiac Disease, supplementation is a good idea.

The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316433/

Nutritional Imbalances in Adult Celiac Patients Following a Gluten-Free Diet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8398893/

@Gilly M,

Have you tried taking a whole capsule of B Complex for several days before starting the additional thiamine?

We can use personal messaging through the forum.

@Jenn D,

I wouldn't worry about it because his numbers are coming down.  

Liver function changes following the introduction of a gluten-free diet in patients with celiac disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977883/

Supplementing with vitamins and minerals to ensure sufficient nutrients can help.

The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316433/

And...

Thiamine and benfotiamine: Focus on their therapeutic potential

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682628/

On 2/8/2024 at 1:12 AM, LadyofLove said:

Does any one know how long it will be until the dairy issue going to go away after being gluten free?

I feel better but doing as my dietician says and trying to reintroduce proper dairy is causing a lot of issues.

Hello I’m new but I thought I’d ask here  i am currently gluten free after said celiac diagnosis and have been for 7 months I do feel better I was almost in the hospital which is how bad it got until people started to listen to me. Previously I was dairy free for only a month but have been lactose intolerant for atleast a decade. Because I suffer from a bowel disease I have a dietitian who now tells me to try full dairy again by reintroducing it because “gluten is the issue” however I have tried repeatedly to do this but when i try I causes massive bowel problems, pain and so.
 

More info:
(I can’t take soya milk since that brought me up in rash I also can’t seem to tolerate milk. However some foods with little soy or dairy allows me to have small solid rather than D)

 

TiA X

Hey, lady,

Some people, because of their genetics, stop producing LactAse, the enzyme that digests the sugar (LactOse) in dairy, when they become adults.

Some people with Celiac Disease have digestive problems after  consuming milk and dairy products because the villi in the small intestine have been damaged by the autoimmune response to gluten.  The villi secrete digestive enzymes like LactAse and absorb nutrients from our food like anemone filtering seawater.  Damaged villi cannot produce LactAse nor absorb nutrients well.  It can take two years or longer to heal the digestive tract.  

Some people with Celiac Disease have digestive problems after consuming dairy because they react to the protein in dairy, Casein, because casein resembles the protein gluten, and they have an autoimmune response to Casein the same as to gluten exposure.  

I found following a low histamine Paleo diet very helpful in recovery.  I like Dr. Sarah Ballantyne's book The Paleo Approach.  The AIP diet cuts out inflammatory foods, foods high in plant Lectins (grains, legumes, seeds and nuts), processed foods, dairy, soy and nightshades.  After a few weeks when my symptoms abated, I added in foods singly and slowly and noted reactions in my food mood poo'd journal.  

I also boosted my absorption of nutrients by taking B Complex, Vitamin D and minerals.  I also took Benfotiamine a form of Thiamine that has been shown to promote healing in the intestines.  

Here's links to discuss with your dietician...

Thiamine and benfotiamine: Focus on their therapeutic potential

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682628/

The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316433/

Mucosal reactivity to cow's milk protein in coeliac disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810502/

Keep us posted on your progress!

@Kara Anne,

Yes, I gained weight. 

Celiac Disease affects the ability to absorb sufficient nutrients due to damage in the small intestine.  Nutritional deficiencies are common in celiac disease and need to be corrected as quickly as possible.  Supplementing with essential vitamins and minerals boosts our body's ability to absorb these nutrients and return to health.

Thiamine deficiency causes weight gain.  A diet high in carbohydrates demands more Thiamine Vitamin B1 to turn carbohydrates into energy.  When there's insufficient Thiamine, more carbohydrates are turned into fat and stored in the body (usually that abdominal fat that is so hard to shift).  We need a minimum of half a gram more of Thiamine for every extra thousand calories of carbohydrates.  

Many high carbohydrate, high calorie foods do not contain sufficient thiamine and other B vitamins needed to turn them into energy instead of being stored as fat.  

During illness, emotional stress and physical exertion, we need more Thiamine.  Running to the bathroom while worrying if you'll get there before having an accident meets those criteria.  

Weight gain is also associated with the development of pre-diabetes and diabetes.  Studies have shown that the majority of Diabetics have thiamine deficiency. 

Here's an article that explains...

Hiding in Plain Sight: Modern Thiamine Deficiency

Drs. Chandler Marrs and Derrick Lonsdale

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533683/

@mrsdelore,

Your antibody tests may be giving inconclusive results because you are not eating sufficient gluten consistently to get your antibody production up to a level that is measurable in the bloodstream.  Diabetes, anemia and Thiamine deficiency can affect antibody production, causing false negatives, too.

In an earlier post, you had two positive DGP tests.  DGP antibodies show up in the bloodstream before tTg antibodies antibodies do.  TTg antibodies are produced in the intestines and then move into the bloodstream if gluten is consistently consumed.  Your inconsistent consumption of gluten is affecting your test results. 

Steroids given to you in December were given to reduce inflammation and the immune response to RSV.  Those steroids will also reduce the immune response to gluten in Celiac Disease.  So, it's no wonder your symptoms of suspected Celiac Disease have lessened.  It's a band-aid.  Your symptoms of suspected celiac disease will return when the steroids wear off. 

Have you had a genetic test for Celiac Disease?  If you have Celiac Disease, you will have celiac disease genes that never change, no matter if you eat gluten or not.  

In order for your upcoming endoscopy to show damage caused by anti gluten antibodies, you need to be eating sufficient gluten consistently.  

According to recent research, updates to the gluten challenge are being implemented.
Recommended intake of gluten should be increased to 10 grams of gluten per day for at least two weeks.  Several months may be necessary.

While three grams of gluten will begin the immune response, ten grams of gluten is needed to get antibody levels up to where they can be measured in serum antibody tests and changes can be seen in the small intestine.  

Keep in mind that there are different amounts of gluten in different kinds of bread and gluten containing foods.  Pizza crust and breads that are thick and chewy contain more gluten than things like cake and cookies.  

A slice of bread can contain 2 grams of gluten, so five slices of bread would equate 10 grams of gluten.

References:
https://www.beyondceliac.org/celiac-disease/the-gluten-challenge/

And...
Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878429/?report=reader

 "In our study, limited changes in Vh:celiac disease (villi height vs crypt depth - aka damage to the small intestine)  following 14-day challenge with 3 g of gluten were observed, in accordance with Sarna et al.  While the 3 g dose was sufficient to initiate an immune response, as detected by several biomarkers such as IL-2, the 10 g dose was required for enteropathy within the study time frame. Based on our data, we would suggest that gluten challenge should be conducted over longer durations and/or using doses of gluten of ≥ 3 g/day to ensure sufficient histological change can be induced."

Keep us posted on your progress!

Welcome to the forum, @misslemon!

You can get a genetic test for any of the genes known to cause Celiac Disease which would not require eating gluten.  Having the genes and improvement on a gluten free diet can be a diagnosis of Celiac Disease.  

You also stated you get a rash when you ate breadsticks.  That rash could be Dermatitis Herpetiformis which occurs in Celiac Disease.  A biopsy of skin next to a dermatitis herpetiformis blister can be taken, specially stained and examined for antigluten antibodies in the skin.  Dermatitis Herpetiformis is a diagnosis of Celiac Disease.

Anemia, Diabetes and Thiamine deficiency can affect antigluten antibody production in those with long-term undiagnosed untreated Celiac Disease.  False negatives on blood tests are possible in long standing untreated Celiac Disease.

You can have an endoscopy without a prior gluten challenge to take biopsies to examine for microscopic changes indicative of damage due to Celiac Disease.  

Celiac patients can have malabsorption problems that can result in serious health consequences.  One example is osteoporosis.  Carpal tunnel syndrome and peripheral neuropathy, anxiety and depression are other examples.  

With your strong family history of Celiac Disease and your symptoms, I suggest you at least get a genetic test.  

Keep us posted on your progress!

Welcome to the forum, @Ecann74!

@trents is right.  You don't have to check every box to Bingo for Celiac Disease.  The high IgA, IgG and positive genes are sufficient for a Celiac diagnosis.

In fact, this study found that negative Endomysial antibodies might be related to long lasting untreated coeliac disease. 

Endomysial antibody‐negative coeliac disease: clinical characteristics and intestinal autoantibody deposits

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856451/

Hope this helps!  Keep us posted on your progress!

@Jjk1992,

Welcome to the forum!

Having a slightly positive test result warrants more investigation.  

Like @trents said, a slightly positive result can be a reflection of decreased gluten consumption prior to the test.  It's like being told you're a little pregnant.  

Was your Total IgA taken?  If you have low Total IgA, your tTg IgA can be low, too.  

Do you have anemia, Diabetes or Thiamine deficiency?  These can cause low tTg IgA results.

Chronic inflammation as occurs in years of undiagnosed, untreated Celiac Disease can cause low tTg IgA results.  

Subclinical vitamin deficiencies as occurs in undiagnosed, untreated Celiac Disease can result in low tTg IgA antibodies.  

Your symptoms "GERD, indigestion, chronic migraines, extreme fatigue and brain fog, joint pain, and bloating" are symptoms of nutritional deficiencies.  Thiamine Vitamin B1 and B Complex deficiencies can cause Gerd, chronic migraines, extreme fatigue and brain fog, and bloating.  Joint pain can be caused by deficiency in Vitamin D.  These are common deficiencies found in untreated Celiac Disease.  

Have you had a genetic test for Celiac Disease genes?  Since celiac disease is genetic, checking for the presence of celiac disease genes is important.  

Hope this helps!  Keep us posted on your progress!