I take 250mg with each meal and snacks. I read a book "Niacin, the real story" by Drs. Hoffer, Saul, and Foster, which advocates high doses. I started small and am increasing my dosage. I'm often sceptical of "cure-all," fad diet, latest health craze books, but this one confirms the research I did prior to stumbling across this book. I have experienced...