knitty kitty

Nutritional deficiencies caused by undiagnosed, untreated Celiac Disease can cause symptoms like you describe.  Malabsorption of nutrients is caused by damage to the intestinal lining which makes absorbing essential nutrients difficult.  We need to absorb sufficient vitamins and minerals from our diet everyday to make sure our body functions properly.

Different vitamins and minerals can be stored for different amounts of time, but usually one of the first to become insufficient is Thiamin Vitamin B 1.  

Every cell in our bodies uses Thiamin as an energy source to do cell functions, especially the brain.  Our brain just sitting and thinking uses as much thiamine as muscles do running a marathon.  

Emotional trauma and physical trauma can each precipitate thiamine deficiency disorders.  

Thiamine deficiency disorders can manifest as sudden weight loss (without trying to lose weight),  OR sudden weight gain.  Pins and needles (paresthesia, neuropathy), muscle aches and cramps, forgetfulness and brain fog, insomnia, frequent urination, constipation and/or diarrhea, and abdominal pain are all symptoms of deficiencies in Thiamine and other B vitamins.   Gastrointestinal BeriBeri  is caused by Thiamin deficiency with the symptoms of nausea and abdominal pain.  

Doctors are not well educated in nutritional deficiencies, so deficiency symptoms are often brushed aside and ignored or attributed to other things.  

Blood tests are not accurate measures of thiamine or other B vitamin deficiencies.  The best way to determine a thiamine deficiency is to take thiamine and look for improvement of symptoms. Symptoms should improve within hours or days.  Doctors can administer thiamine intravenously for faster results, but over-the-counter Benfothiamine (an active form of thiamine) works just as well.  Thiamine is not harmful to be administered because thiamin is water soluble, meaning excess is easily excreted by the kidneys.  Thiamine is nontoxic even in high doses. 

Thiamine helps with PTSD and C-PTSD.  PTSD happens after one traumatic event or series of events.  C-PTSD happens after being chronically traumatized, day after day, frequently starting in childhood.  An example of Chronic PTSD would be a child being told their stomach aches were faked to get out of going to school because the child was really just lazy, when in reality the child has undiagnosed active Celiac Disease and diverticulitis.  My blog on this site has more information on my journey and thiamine deficiency.

Do talk to your doctor and nutritionist about correcting nutritional deficiencies that accrue in Celiac Disease.  Ask about Gastrointestinal BeriBeri.

@Travel Celiac,

Doing a happy dance with you!!!  You're doing very well!!!  Kudos for being a rescuer!  Hip Hip Hooray!

Yes, strenuous exercise can raise your IgA, as can viral infections like the common cold or Covid.  

https://pmc.ncbi.nlm.nih.gov/articles/PMC9574171/

Do discuss with your doctor the nutritional deficiencies that frequently occur in Celiac Disease and on the gluten free diet.  Deficiencies in zinc, iron, the B vitamins, Vitamin C and Vitamin D can all affect your ability to fight off viruses and repair stressed muscles.  

@Kipman,

Ask for a genetic test to determine if you have any of the known genes for Celiac Disease.  

Anemia, Thiamine deficiency and diabetes can each cause false negatives and low IgA.  You may want to investigate these further with your doctor.

Celiac Disease can occur with Ehlers-Danlos Syndrome, another genetic autoimmune disease.  Ehlers-Danlos is a connective tissue disease frequently seen in people who are double jointed or have stretchy skin.  This stretchy-ness can affect the digestive system.  

https://pubmed.ncbi.nlm.nih.gov/27321543/

Welcome to the forum, @Travel Celiac!

You have to be consuming gluten for your body to trigger the autoimmune response and produce anti-gluten antibodies.  If you're not consuming gluten, the autoimmune response is not triggered and you won't produce anti-gluten antibodies. 

Celiac Disease is genetic.  Your genes don't change.  You will always have the Celiac genes whether you eat gluten or not.  

Your negative tTg-IgA  shows that you are successfully keeping gluten out of your diet.  You are doing very well on that point, but you still are Celiac.  Be proud of your accomplishment!  

@Whyz,

I take a combination of Thiamin (Benfotiamin), B12 Cobalamine and Pyridoxine B6 for my pain and headaches.  Really works well without hurting the digestive tract.  Riboflavin B2 also helps with migraines.  Most newly diagnosed people have vitamin and mineral deficiencies.  Check with your doctor and nutritionist.  

If you follow the updated gluten challenge guidelines, you can wait until two weeks (minimum) before your appointment, then eat lots of gluten, like six slices of gluten containing bread or "name your poison".  

Here's the Updated Gluten Challenge Guidelines:

Recommended intake of gluten should be increased to 10 grams of gluten per day for at least two weeks. Or longer.

While three grams of gluten will begin the immune response, ten grams of gluten is needed to get antibody levels up to where they can be measured in antibody tests and changes can be seen in the small intestine.  

Keep in mind that there are different amounts of gluten in different kinds of bread and gluten containing foods.  Pizza crust and breads that are thick and chewy contain more gluten than things like cake and cookies.  

References:

https://www.beyondceliac.org/celiac-disease/the-gluten-challenge/

And...

Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878429/?report=reader

 "In our study, limited changes in Vh:celiac disease (villi height vs crypt depth - aka damage to the small intestine)  following 14-day challenge with 3 g of gluten were observed, in accordance with Sarna et al.  While the 3 g dose was sufficient to initiate an immune response, as detected by several biomarkers such as IL-2, the 10 g dose was required for enteropathy within the study time frame. Based on our data, we would suggest that gluten challenge should be conducted over longer durations and/or using doses of gluten of ≥ 3 g/day to ensure sufficient histological change can be induced."
Keep us posted on your progress!

Welcome to the forum!

Keep in mind that if you quit eating gluten before all testing is done, you may have inaccurate, possibly false negative, test results.  When you stop eating gluten, your body stops making the antibodies which are measured in the blood tests.  Stopping gluten before an endoscopy may make the intestinal damage harder to detect, and a false negative biopsy may result.  As uncomfortable as it is, finish all testing before going gluten free.  

Since you're having a last hurrah with gluten, request another round of blood tests for celiac antibodies.  Make sure you're eating ten grams or more daily for those few weeks before your capsule endoscopy.  You probably weren't eating a sufficient amount of gluten needed to provoke sufficient antibody production. 

Hashimoto's is a type four hypersensitivity.  

Read what this doctor did about hers...

https://thyroidpharmacist.com/articles/food-sensitivities-and-hashimotos/

She adopted a Paleo diet.

Once you get your inflammation down, and your nutrients up, your body's immune system can calm down and quit reacting to every little thing.

@GardeningForHealth,

On my journey, I found following the Autoimmune Paleo Diet most helpful in reducing reactions to various foods.  It's very restrictive, but it really helps improve gut health.  It's worth the effort for a few weeks or months.

Tea from any grocery store; Tea, organic; Tea, grown in USA, never-sprayed, loose leaf

Tea contains TANNINS which can inactivate Thiamin resulting in Thiamin deficiency.  Tannins inhibit the absorption of other vitamins and minerals, especially iron. Tannins can inactivate digestive enzymes.  So drink tea between meals.  Choose a tea with lower levels of tannin, like green tea or Oolong tea.  Oolong tea contains amino acid Theanine which reduces inflammation in the digestive tract.

Dairy; Rice, any brand, even after washing 3 times

Many people develop Lactose intolerance because damaged villi in the intestinal lining of the digestive tract cannot produce the enzyme Lactase needed to digest the sugar in dairy, Lactose.  

Many people with Celiac Disease react to the protein Casein the same as they react to the protein Gluten.  This is because both Casein and Gluten, as well as the protein in rice, carry a similar segment of a protein building block chain (33 mer peptide) that triggers the autoimmune response in Celiac Disease.  Basmati rice is less likely to carry this protein chain and may be better tolerated.  Don't wash rice before cooking.  The added vitamins get washed away.  Some of those grains of rice are extruded vitamins.  They dissolved into the cooking water and are reabsorbed into the grains as the rice cooks.

Organic catchup, Potatoes;

Tomatoes are a member of the Nightshade vegetables which have been shown to increase gastrointestinal permeability and "leaky gut syndrome."  Potatoes, Peppers and Eggplant also belong to the Nightshades, and should be avoided until healed.  Catsup usually is acidic which can be irritating to the digestive system.

Any and all brands of gluten-free breads and dessert items; Cassava flour; Gluten-free flour

Often these contain cross contamination with gluten.  @Scott Adams recently posted a new article about this.  Gluten free products are not enriched with vitamins and minerals needed to digest and process them.  They are high in insoluble fiber and saturated fats.  These may also contain microbial transglutaminase, see below.

Sausage, Any processed meat

These foods contain microbial transglutaminase, a flavor and texture enhancer, called "meat glue" in the food processing industry, which triggers and provokes anti-gluten antibodies to attack the microbial transglutaminase as well as the tissue transglutaminase produced by our own bodies as with Celiac Disease.  We have articles about microbial transglutaminase, too.  Cassava also contains Thiaminase, an enzyme which destroys Thiamin.

Cucumbers from a grocery store, but not from my garden, Most apples, Zucchini, Plums

Cucumbers, like these other fruits and veggies, contain lots of soluble fiber, pectin, which intestinal bacteria can ferment and then make short chain fatty acids, which are beneficial.  So that's a good thing.  However, commercially produced breeds of veggies and fruits may contain higher levels of pectins than historically home grown varieties.  Excess consumption of pectins can result in gas, bloating and diarrhea.  

Bottled spices 

There's an article (perhaps @Scott Adams can help us find, please) about how some spices can cause gastrointestinal symptoms.

Gluten-free dairy-free ice cream

These can cause reactions if one reacts to oats.  Products made from nuts or nut milks may contain high levels of lectins which are hard to digest and can cause all the usual symptoms.  

Smoke from a fire; Strong cleaning chemical fumes

These contain Sulfites.  Developing a hyperensitivity to Sulfites is possible in Celiac Disease.  We can be low in vitamins and minerals needed to process Sulfites.  I have Hypersensitivity Type Four where the immune system identifies Sulfites as something to be attacked.  Celiac Disease is another Hypersensitivity Type Four disorder.

Packaged sweet potato chips; Packaged plantain chips;  Rice; Any and all brands of gluten-free breads and dessert items; Cassava flour; Gluten-free flour; Gluten-free dairy-free ice cream

A High Carbohydrate diet can lead to Small Intestinal Bacterial Overgrowth (SIBO).  Adopting a Paleo diet like the AIP diet is a great way to change your gut biome without using antibiotics which kill off the bad with the good bacteria.  Taking probiotics may not be very effective as long as SIBO bacteria are entrenched in the digestive tract.  You change what you eat and you change what grows inside you.  You starve out the bad SIBO bacteria, repopulate and feed the good ones.  Supplementing with Benfotiamin helps because thiamine has antibacterial properties that keeps the bad bacteria in check and benefits the good bacteria.  Benfotiamin is needed to process all those carbs turning them into energy instead of them turning to fat.  

I hope this has been helpful.

Gluten can cause inflammation in the digestive tract and that includes the mouth.  Also, nutritional deficiencies can cause oral inflammation.  Cobalamine B12 deficiency and Niacin B3 deficiency can result in swollen irritated tongues and mouth sores.  Salt would definitely cause further irritation.... Like pouring salt in a wound....

@Barcino,

Yes, do try cutting out dairy.  About half of people with Celiac Disease react to the protein in dairy, Casein, the same as to gluten because of similar protein segments.  Others have Lactose intolerance because their damaged intestinal lining, the villi, are damaged and can't produce the enzyme lactase which breaks down the sugar in dairy, Lactose.  

Also, cut out processed gluten free foods.  Many gluten free processed foods use corn.  Some people with celiac disease react to corn the same as to the protein gluten because of similar-to-gluten protein segments of maize, the protein in corn.   Processed foods containing corn may also utilize microbial transglutinaminase to bind corn proteins together to improve texture.  Microbial transglutaminase is also used in dairy products like yogurt and ice cream to bind dairy protein casein together to improve texture.  Microbial transglutinaminase is not required to be listed as an ingredient because it is an enzyme considered to be part of the manufacturing process.  The increasing usage over the past couple of decades of microbial transglutaminase to cross link gluten proteins together in wheat containing products is suspected to be a trigger of Celiac genes, hence the increased numbers of people being diagnosed with celiac disease recently.

Do consider supplementing with Benfotiamine, a form of Thiamin Vitamin B One, that has been shown in scientific studies to promote intestinal healing.  It also helps acne along with Niacin Vitamin B 3.  Vitamin D helps lower inflammation, and Vitamin C helps rebuild and repair damage.   

I've had great improvement following the Autoimmune Protocol diet.  The AIP diet has been scientifically shown to improve intestinal health, too.  Developed by Dr. Sarah Ballantyne, a Celiac for her Celiac children.  It really does work quickly to reduce inflammation.  Although terribly strict,  improvement happens within a few weeks.  

Hope this helps.  Keep us posted on your progress!

Many probiotics start with growing the bacteria on a dairy substrate leaving traces of dairy in the probiotics.  

Many Celiacs react to dairy in the same way as they react to gluten because certain protein chains in dairy resemble gluten protein chains.  

@Wheatwacked ferments his own pickles.  Perhaps he can chime in.

The AIP diet does have a vegetarian version.  

Dr. Sarah Ballantyne developed the AIP diet for herself and her children, all Celiacs.  The AIP diet has been shown in scientific studies to promote intestinal healing.  You might visit her website.  https://www.thepaleomom.com/ 

@BoiseNic

Have you tried the Autoimmune Protocol Diet?  This Paleo diet cuts out most everything except meat, veggies and some fruits.  By cutting out all the carbohydrates, especially processed ones, the carbohydrate loving bacteria and fungi like Candida get starved out and die off.  After that, taking probiotics to help repopulate the gut is beneficial.  The new strains of bacteria don't have to fight the established unhealthy yeasts and bad bacteria which causes a rise in histamine levels which can make one feel sick.  

Certain vitamins help keep bad bacteria and fungi at bay.  Thiamine is one.  Antibiotics can deplete Thiamine stores.  The Gluten free diet can be low in Thiamine and the other vitamins and minerals needed for healthy skin and digestive tract.  Vitamin C, Vitamin D, zinc, and Niacin B 3 are important to skin health.  Niacin is especially helpful in Dermatitis Herpetiformis.  I like the kind that flushes (Nicotinic Acid - not the same as nicotine in cigarettes).  The flushing gets less and less the longer it's taken, but Niacinamide which doesn't cause flushing can be taken instead.    

Here's an interesting article.  Compare the bacteria mentioned in the article with your Skinesa and then with the Visbiome probiotics.  

The Role of Probiotics in Skin Health and Related Gut–Skin Axis: A Review

https://pmc.ncbi.nlm.nih.gov/articles/PMC10385652/

Visbiome

https://www.visbiome.com/collections/all/products/visbiome-capsules

@Juliana82,

Is the bleeding occurring when you throw up?  Or with bowel movements?  Constipation?  Is it bright red or black and tarry?  Anal fissures?  Crohn's or Colitis?  Alcohol consumption?  

Diabetes, Thiamine deficiency and anemia can cause false negatives.  Most diabetics are deficient in Thiamine.  Thiamine deficiency can also occur due to high calorie malnutrition, eating lots of carbohydrates but insufficient Thiamine from dietary sources.  

The Gluten-Free Diet for Celiac Disease: Critical Insights to Better Understand Clinical Outcomes

https://pmc.ncbi.nlm.nih.gov/articles/PMC10537989/

@Vozzyv,

Certain nutritional deficiencies can cause tinnitus, ringing in the ears.  Vitamins A and D, Thiamine B1, Riboflavin B2,  Pyridoxine B6, Folate B9,  Cobalamine B12, magnesium, zinc and Vitamin C can cause tinnitus individually if deficient.  The malabsorption of Celiac Disease affects all the nutrients our bodies need.  Many of these nutrients work together to keep us healthy.  

Talk to your Nutritionist and doctor about supplementing vitamins and minerals while healing.  Eat a nutritionally dense diet.  

Tinnitus has been bothersome to me, but supplementing with the B vitamins, especially Thiamine, Vitamin C, and Vitamins A and D has really helped me.  

@Milarynn, 

Welcome to the forum!  

Many undiagnosed, untreated Celiac Disease patients have vitamin and mineral deficiencies.  Be sure to have your Vitamin D level checked.  Vitamin D helps prevent bone loss, including loss from the jaw and teeth.  

Magnesium and calcium are both important to bone health as well.  Magnesium helps keep the calcium from leaving your bones.  Magnesium helps make life sustaining enzymes with Thiamine Vitamin B1.  Low Magnesium and/or low Thiamine results in muscle cramping.  

Thiamine deficiency is found in Pre-diabetes and Diabetes.  Poor absorption of the eight water soluble B vitamins and Vitamin C are found in Celiac Disease.  Insufficient Vitamin C can cause poor oral health, resulting in poor gum health such as receding and bleeding gums.  Vitamin C is needed to fight bacteria that cause plaque which causes cavities.  Vitamin C helps rebuild tooth enamel.  

I've had jaw muscle cramping, TMJ problems, tooth loss and gum problems.  Do talk to your dentist about having Celiac Disease.  Practice good oral hygiene.  I'm also Diabetic and take Benfotiamine (a form of Thiamine) that helps regulate blood glucose and heal the intestines.

Do keep us posted on your test results and your progress!

@CeliacPsycho246,

You might try cutting out dairy.  Some of us react to Casein, the protein in dairy, the same as to gluten.  

"Doses higher than the RDA are sometimes used to treat medical problems such as vitamin D deficiency, but these are given only under the care of a doctor for a specified time frame. Blood levels should be monitored while someone is taking high doses of vitamin D."

Quoted from the Healthline article @Yaya linked above...

https://jamanetwork.com/journals/jama/fullarticle/2748796

If read carefully, this study @Yaya refers to was done on healthy people.  

"Meaning  Among healthy adults, supplementation with higher doses of vitamin D did not result in improved bone health; further research would be needed to determine whether it is harmful."

"...311 community-dwelling healthy adults without osteoporosis, aged 55 to 70 years, with baseline levels of 25-hydroxyvitamin D (25[OH]D) of 30 to 125 nmol/L."

High dose Vitamin D doesn't have substantial benefits if your Vitamin D level is already normal.

High dose Vitamin D is used to restore severely deficient Vitamin D levels to normal levels. 

"...high-dose vitamin D therapy, as a useful tool to rapidly replete vitamin D status, may support immune function in the context of an acute or chronic infection" ...and... "Therefore, in the context of inflammation and conditions where anemia is prevalent, including chronic kidney disease, cardiovascular disease, and critical illness, high-dose vitamin D supplementation may be beneficial in rapidly repleting and maintaining 25(OH)D concentrations and may serve as a complement to other treatment regimens to improve anemia."

"Among those who had insufficient 25(OH)D (<75nmol/L) at baseline, the High Dose group improved significantly and to a comparatively greater degree on the PRM."

These quotes are from the articles I posted earlier.

Oh, @Yaya!

Five years???  How awful for you to suffer so long!

My Vitamin D came up in a matter of months.  High dose Vitamin D has been used in the past to correct rickets and is a safe method to correct Vitamin D deficiency.  

I took 1000 IU several times a day, every day for several weeks.  I ate them like m&m's when I was severely deficient.  My brain craved them.  I felt so much better afterwards.  On maintenance dose now.  Yes, the craving went away as my level reached 80-95.  

Ask your cardiologist about supplementing with.Benfotiamine.

@CeliacPsycho246,

My OCD symptoms resolved after I took supplements of the active form of Pyridoxine B6 called P5P and L-Theanine, an amino acid.  

Pyridoxine B6 is absorbed from foods or supplements and then must be changed to its active form.  P5P is the active form.  Inflammation and malabsorption can impede this process.  Taking the active form is beneficial because it is ready to be used immediately.  

L-Theanine is a natural amino acid that helps immensely with anxiety.   Together these two supplements really work to relieve OCD.

I like Life Extension brand of P5P, but there are others that are labeled gluten free, too.  L-Theanine is found in chocolate, but as much as I love chocolate, Theanine  supplements work better.   Hope you are open to trying these as a stop-gap until your doctor's appointment.  Keep us posted on your results.

Hello, I'd have been here sooner, but I got tangled up in yarn...

Restless leg syndrome (RLS) I've had. It's often associated with iron deficiency and B12 deficiency, but can also show up with any deficiencies in Vitamin C, copper, Vitamin D, and Thiamine, Pyridoxine, and magnesium.  B12, Thiamine, and Pyridoxine will also help with peripheral neuropathy, that burning sensation.  

(See... https://pmc.ncbi.nlm.nih.gov/articles/PMC9804944/ )

Long Covid can be the result of nutritional deficiencies, as well.  Zinc, Selenium, Vitamin D, B12, Thiamine, Riboflavin, Pyridoxine, Niacin, and Choline.  (See... https://pmc.ncbi.nlm.nih.gov/articles/PMC10015545/  and https://pubmed.ncbi.nlm.nih.gov/36587225/ )

I agree with @Wheatwacked to get Vitamin D level higher, 80 ng/ml.  Taking high doses of Vitamin D to correct a deficiency has been found to be beneficial.  I took Vitamin D3 supplements throughout the day when I had a severe deficiency.  It got my level up quickly and I started feeling much better.  

(See... https://pubmed.ncbi.nlm.nih.gov/28167237/ , https://pmc.ncbi.nlm.nih.gov/articles/PMC4824637/)

Vitamin D is a fat soluble vitamin.  Fats can be difficult to digest and absorb, so most of the newly diagnosed can be low in the four fat soluble vitamins (A,D,E,K).  A deficiency in Vitamin A can cause dry eyes.  Omega Threes and Evening Primrose Oil help with dry eyes, too.  (https://pmc.ncbi.nlm.nih.gov/articles/PMC10363387/)

Blood tests are not accurate measurements of vitamin levels.  Blood tests will reflect any supplements being taken.  Blood tests do not measure how much of a vitamin is stored inside cells.  Supplementing with all eight essential B vitamins for several months will boost your ability to absorb the needed nutrients.

A deficiency in Cobalamine, B12, can be aggravated by anesthesia.  Cobalt in Cobalamine binds irrevocably, irreversibly with the Nitrogen in anesthesia, rendering B12 useless.  Supplementing with B12 after exposure to anesthesia is beneficial.  (https://pubmed.ncbi.nlm.nih.gov/8250714/)

Pyridoxine B6 and Riboflavin B2 as well as B12 are needed to lower histamine levels (produced during the inflammation process that occurs in Celiac Disease). This can help relieve the sinus pressure.  Riboflavin B2 and Thiamine B1 are helpful with headaches.  

We need more Thiamine when we are emotionally stressed, physically ill, and physically active.  Benfotiamine, a form of Thiamine, has been shown to promote intestinal healing.  Thiamine is helpful in relieving anxiety.  

(https://pmc.ncbi.nlm.nih.gov/articles/PMC10682628/  , https://pmc.ncbi.nlm.nih.gov/articles/PMC8451766/ )

Celiac Disease causes malabsorption of vitamins and minerals.  It is rare to have a single vitamin deficiency.  Malabsorption in celiac disease affects all the nutrients we need.  Some vitamins just run out sooner than others because they can't be stored or we have a metabolic need for more.  (https://pmc.ncbi.nlm.nih.gov/articles/PMC10106602/ )

Hope this helps!

@glucel,

I agree with @trents.  You can still do the AIP diet while taking aspirin.  

I'm one of those very sensitive to pharmaceuticals and have gotten side affects from simple aspirin. 

Cardiac conduction abnormalities and atrial arrhythmias associated with salicylate toxicity

https://pubmed.ncbi.nlm.nih.gov/3952006/

Another part of the problem is that those drugs, aspirin and warfarin, as well as others, can cause nutritional deficiencies.  Pharmaceuticals can affect the absorption and the excretion of essential vitamins, (especially the eight B vitamins) and minerals.  

Potential Drug–Nutrient Interactions of 45 Vitamins, Minerals, Trace Elements, and Associated Dietary Compounds with Acetylsalicylic Acid and Warfarin—A Review of the Literature

https://pmc.ncbi.nlm.nih.gov/articles/PMC11013948/

Aspirin causes a higher rate of excretion of Thiamine Vitamin B1.  Thiamine deficiency can cause tachycardia, bradycardia, and other heart problems.  Other vitamins and minerals, like magnesium, are affected, too.  Thiamine needs magnesium to make life sustaining enzymes.  Without sufficient Thiamine and magnesium and other essential nutrients our health can deteriorate over time.  The clinical symptoms of Thiamine deficiency are subtle, can easily be contributed to other causes, and go undiagnosed because few doctors recognize Thiamine deficiency disorders.

Thiamine deficiency disorders: a clinical perspective

https://pmc.ncbi.nlm.nih.gov/articles/PMC8451766/

Hiding in Plain Sight: Modern Thiamine Deficiency

https://pmc.ncbi.nlm.nih.gov/articles/PMC8533683/

Celiac Disease causes malabsorption of vitamins and minerals.  Supplementing with essential vitamins and minerals can boost absorption.  

Our bodies cannot make vitamins and minerals.  We must get them from our diet.  The Gluten free diet can be low in Thiamine and the other B vitamins.  Gluten free processed foods are not required to be enriched nor fortified with vitamins and minerals like their gluten containing counterparts.

You would be better off supplementing with essential vitamins and minerals than taking herbal remedies. 

Turmeric is known to lower blood pressure.  If you already have low blood pressure, taking turmeric would lower it further.

Curcumin/turmeric supplementation could improve blood pressure and endothelial function: A grade-assessed systematic review and dose-response meta-analysis of randomized controlled trials

https://pubmed.ncbi.nlm.nih.gov/38220376/

I've taken Benfotiamine for ten years without any side effects, just better health.

Other References:

Association of vitamin B1 with cardiovascular diseases, all-cause and cardiovascular mortality in US adults

https://pmc.ncbi.nlm.nih.gov/articles/PMC10502219/

Prevalence of Low Plasma Vitamin B1 in the Stroke Population Admitted to Acute Inpatient Rehabilitation

https://pmc.ncbi.nlm.nih.gov/articles/PMC7230706/

Bradycardia in thiamin deficiency and the role of glyoxylate

https://pubmed.ncbi.nlm.nih.gov/859046/

Aspirin/furosemide:  Thiamine deficiency, vitamin C deficiency and nutritional deficiency: 2 case reports

https://pmc.ncbi.nlm.nih.gov/articles/PMC9023734/

Hypomagnesemia and cardiovascular system

https://pmc.ncbi.nlm.nih.gov/articles/PMC2464251/

Atypical presentation of a forgotten disease: refractory hypotension in beriberi (thiamine deficiency)

https://pubmed.ncbi.nlm.nih.gov/31285553/

Hi, @Dawn R.,

I get gluten ataxia.  It's very disconcerting.  

Are you still experiencing gluten ataxia symptoms eating a gluten free diet?