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docaz

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Celiac.com - Celiac Disease & Gluten-Free Diet Support Since 1995

Everything posted by docaz

  1. docaz
    GliadinX is safe to take every day and even multiple times during the day because GliadinX does not accumulate in the body, It is only effective in the stomach to break down the proline bindings of the gluten proteins. GliadinX does not leave the GI tract and is excreted in the stool. Also as Trents wrote it is safe and only costs a little over 50 cents...
  2. docaz
    Hi, I am actually the "suspect" sponsor and I have developed the product for my own children based on the existing data and not based on hype but based on collaboration with the former head of the University of Chicago Celiac Center and the head of the GI department at Leiden University who performed some the original studies in 2006. If the owner...
  3. docaz
    These findings are very helpful because they might obsolete unnecessary biopsies but they do beg the question of why even measuring IgA as a standard celiac screening test if it does not correlate with the disease.
  4. docaz
    This is a paper that I just recently discovered by Dr. Stefano Guandalini who is Professor Emeritus and the founder of the University of Chicago Celiac Center. Please not on the last page before the references the diagram (the image with the scissors) explaining how AN-PEP (GliadinX) works https://www.researchgate.net/profile/Stefano-Guandalini/publication...
  5. docaz
    When my kids were diagnosed, I must admit that it was quite overwhelming for me also but it for sure gets easier as you learn how to deal with it. It is easier in urban areas where there are more gluten free restaurants but most supermarkets have lots of gluten free options. Regarding AN-PEP, you can go on google scholar and enter the terms: aspergillus...
  6. docaz
    This is the paper from clinicians at the University of Chicago Celiac center writing about GliadinX being able to break down "only" 1/8 of a slice of bread (Section 12). As Scott pointed out, that is a huge step forward given that most contamination is a lot less https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024684/
  7. docaz
    Indeed, unlike other enzymes which are not resistant to acidic environment, GliadinX works best in a low pH and this is what makes it so ideal for breaking down gluten. It actually does not work by itself but in combination naturally occurring enzymes in the stomach because AN-PEP breaks down the proline bindings but the naturally occurring enzymes such...
  8. docaz
    The most common situation is when shared utensils are not adequately cleaned and in that case one capsule is enough. If you find out that you have accidentally eaten gluten after the fact then please take GliadinX as soon as possibly and preferably within 30-90 minutes while the food bolus is still in the stomach. In vivo and in vitro studies have shown...
  9. docaz
    Given the serious problem that we are dealing with, I think that we should dance with glee for every little step we are making forwards including breaking down most of the gliadin and thus eliminating or at least lowering inflammation until we will get to something that will be a real cure. Are we now in agreement that at least SOME gliadin is broken down...
  10. docaz
    You are good mediator. I really do not like to get into arguments but the accusations of false and misleading statements that should not be on this site are harsh and suggest intentional deception. I can see that what I wrote could be misinterpreted. My point was that even small amounts of gluten need to be addressed even it is not 100% it is enough...
  11. docaz
    Please educate us and post a link to the studies that you read that state that NOTHING breaks down gluten. Please post studies and not someone's interpretation or opinion.
  12. docaz
    The statement that NOTHING breaks down gliadin before reaching the small intestine is very, very false. Just to add to all the papers that I posted before, this is a paper co-authored by the head of the GI department of the Mayo Clinic, Dr. Joseph Murray. His opinion is that enzymes can break down gluten in the stomach. https://www.ncbi.nlm.nih.gov/pmc...
  13. docaz
    In some countries, gluten-removed beer can be called gluten-free but I do not know if that applies to the US. The active enzyme in GliadinX (AN-PEP) was first used to speed up the process of making beer clear. It is sold under the name Brewers Clarex. The scientist at DSM who developed the enzyme Luppo Edens realized that in order to make the beer clear,...
  14. docaz
    ABSOLUTELY NOT!! It means exactly what it says. Implying that this is designed to eat gluten freely is a baseless interpretation. The studies show that a small amount of gluten is digested but nowhere is that posted or advertised in conjunction with GliadinX. It is everywhere prominently posted that It is intended for possible cross-contamination and NOT...
  15. docaz
    It is very important to emphasize that nowhere is the product advertised for intentional gluten ingestion. This is done prominently and is not just a hidden footnote. You are very correct that even the smallest amount of gluten (specifically the gliadin molecule) can cause damage in the small intestine. Your are also correct that avoiding gluten is the best...
  16. docaz
    There are a lot of comments suggesting that Scott from celiac.com promotes GliadinX just for the paid advertisement. First of all, before GliadinX was allowed to be an advertiser, the data had to be presented because otherwise it would have never made it on the site. It so happened that Scott had in his family a situation of cross contamination in which...
  17. docaz
    You are absolutely right that it is important to concentrate on maintaining a gluten-free diet and GliadinX is not designed to change that. Even the most careful person will be in a situation that raises questions at a family event, in a social situation or at a restaurant that is not completely gluten-free but has gluten-free items on the menu. The only...
  18. docaz
    Your GI could possibly not be aware of the many studies showing exactly how GliadinX (AN-PEP) breaks down the proline bindings of gliadin. Indeed, gliadin is a very tough protein because it has many proline bindings and the human body does not have the capability to break down these bindings. There are several enzymes that have the capability of breaking...
  19. docaz
    Nobody questions the severity of the disease but please be so kind to read this post and check for yourself the information that is presented and I hope that it will be worth your time. There is a tremendous amount of research that shows that AN-PEP (the active ingredient of GliadinX) withstands the stomach acidity. Even more so, it has the highest activity...
  20. docaz
    Sorry, I meant to write "Scott" not Adam.
  21. docaz
    Be prepared for the GI doctor to have never read the studies about AN-PEP and I would consider just bringing a printout. If the GI doctor can show any data, the AN-PEP does not work (besides one single study that was too short and both, placebo and AN-PEP did NOT have a negative effect) that's one thing, but if he/she just says "no" without any reason like...
  22. docaz
    As Adam mentioned, the goal of the study is to prove (or refute) that GliadinX can break down contaminants which will then not show up in urine and stool samples. The current study does not use a home test kit but is more precise and can also quantify the amount of contamination.
  23. docaz
    Hi, I just happened to read your questions and I am the founder of GliadinX. I would like to mention that there is a major double blind placebo study going on right now. It is going slower than anticipated because of Covid restrictions for elective patient visits but you can read about the study here: https://clinicaltrials.gov/ct2/show/NCT...
  24. docaz
    The best time is to take GliadinX right at the start of the meal. GliadinX works while the food is in the stomach. If it is a very long meal (more than 90 minutes), you can take one more capsule at that time.
  25. docaz
    Hi, At least he was honest. So many physicians have never read an article about enzymatic degradation of gluten and discount it out of ignorance combined with laziness to actually read the papers. Recently, almost every month, a new encouraging publication from various international medical centers is written about this topic. Most of them are literature...
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