pupppy

Edit: nvm I have dq5/dq4

edit: nevermind i will just wait and see what they say. The only other abnormal thing was that my "eos" was slightly *high, and the hct was borderline low (41.0%, range 41.0-50%)

Interestingly, DQ4 is a very rare haplotype in most of the world (freq .03-2%) and is significantly associated with RA. 35/43 (81%) RA patients in a sample study had the DR4-DQ4 type, especially DQ4.1. (subtype of 4.3) https://onlinelibrary.wiley.com/doi/pdf/10.1002/art.1780310111

Yes I see your point, I will go to ask. I hope it’s nothing

One question, did your niece have any positive blood work?

Wow, I guess when I read stories of ibd it seemed more severe, like going to the bathroom 20 times a day and losing weight rapidly. I was afraid to get a diagnosis like IBS or SIBO. I get relief cutting dairy from my diet, and the breath test for lactose intolerance was barely positive (~17-20 ppm increase in h2), so my only curiosity left is the blood test...

Wow thanks. That is some really good information. Yes my vitamin D was very low around two years ago when the results came back, it was 7. The doctor said to supplement and eat more dairy (can’t do that now). I had been ignoring it completely, I never realized the link between RA and vitamin D. I will definitely start supplementing. As far as B vitamins g...

I tested negative for all parasites and I haven't been sick in over 2 years. I also had the hydrogen breath test done which came back positive for lactose intolerance This may be a wild shot in the dark, but is there any association between ttg igg and rheumatoid arthritis? Both my grandmother and aunt have it, and it says the DR4-DQ4 is associated with...

Which disorders? My paternal side have rheumatoid arthritis and psoriasis. It was 10 when I had it checked just last month (which is what led me to get the entire panel). I was hoping, if everything came back negative, that the ttg igg would decrease also and just be a fluke, but it seems to be going up. ? I had mainly digestive problems which is what...

I don't understand the genetic info either but after googling it seems like DQA1*01 = DQ1. And DQB1*04 = DQ4. So DQ1 and DQ4. Edit: DQ1 actually seems to split into DQ5 and DQ6, and upon further investigation it says DQA1*0103. This is listed under wikipedia as DQ6.1. So I have DQ6 and DQ4 (DQB1*0405 = DQ4.3/DR4-DQ4)

Hello, I came back negative on all the celiac tests including the gene test at labcorp except for the ttg igg, which was 12 (range 0-5). My iga is low, but I came back negative on the dgp igg and the gene test which I understand ~100% rules it out. Does this indicate anything other than celiac, or should I ignore it? Results Deamidated Gliadin Abs...

It's not just quest, it's also mayoclinic, the American College of Gastroenterology, ARUP labs, and most algorithms out there. Partial iga deficiency still counts as iga deficiency. As long as it's below the range, the standard is to order igg tests https://gi.org/guideline/diagnosis-and-management-of-celiac-disease/ http://www.lbm-mg.com/lbm-docs...

Well that link is wrong, every testing algorithm I've read stated that if your iga is below the range they order igg tests, and if any result is positive or equivocal proceed to biopsy. There is selective iga deficiency which is <1 mg/dl, and partial iga deficiency which is above that but below age matched ranges. I don't know where they got 20 mg/dl from...

Yes, I understand it has nothing to do with celiac-it measures how much iga your body makes to validate the test. I agree he is not iga deficient because it is in the normal range. What I am saying is, since it is in the low end of normal, it could throw off the results somewhat and give a negative ttg iga. I meant this as an explanation to why his ttg...

You and your link are wrong. Algorithms for testing state that if iga is out of range they should test for igg.